Navigation Links
Scientists locate key hormone involved in appetite control

A key hormone involved in appetite control, called ghrelin, has been identified by researchers from the Oregon Health & Science University(OHSU). Scientists have demonstrated the effect of the hormone on the brain and have shown that the hormone activated the specialized neurons in the hypothalamus involved in weight regulation. Ghrelin is a hormone produced in the stomach with the ability to stimulate feeding when introduced to specialized weight regulating brain cells called neuropeptide Y neurons. Lead author Michael Cowley, Ph.D., added that past// research has shown that increasing ghrelin levels in mice for an extended period resulted in weight gain. Ghrelin is believed to be part of the body's natural signaling system which informs the brain when it's time to eat. In both mice and humans, ghrelin levels increase naturally in response to weight loss or reduced caloric intake and the hormone diminishes in response to food intake.

The scientists used a method pioneered by OHSU researchers Cowley, Roger Cone, Ph.D., and Malcolm Low, M.D., Ph.D. to pinpoint and witness the effects of the hormone in the brain. They used a fluorescent protein to highlight certain neurons, making the brain cells distinguishable from other surrounding neurons. They then used tiny electrodes to record cell activity in response to ghrelin. The researchers have also located a new source for ghrelin production in the body. The site is located in a section of the hypothalamus that had no previously known function and that is near the brain region affected by the hormone.

Researchers believed that this new discovery could be used to develop drugs aimed at stimulating appetite in patients who have undergone extreme weight loss due to illness, a condition known as cachexia, and in finding new drugs that would assist children who are developing at a slower than normal rate. On the other hand, drugs aimed at limiting production of the hormone might be developed to reduce a ppetite for those battling severe obesity. Senior scientist, Cone, also added that future research will help distinguish between the roles of the brain and stomach production sites so that there would be better understanding of weight regulation and energy homeostasis in the body.


'"/>




Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. Scientists found ancient Human Germ Killer
3. Scientists open the book of life
4. Scientists review SARS
5. Scientists crack dengue fever puzzle
6. Scientists push to lower hidden sodium in food
7. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
8. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
9. Scientists reveal the secrets of sarcasm
10. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
11. Scientists Warn Against Food Borne Illnesses
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... ... PurhealthRX , a leading Health and Nutrition Company, is announcing the ... spectrum CBD oil will revolutionize the rapidly growing CBD market by reducing the amount ... into liquid products, while reducing costs to end users. , The team of researchers ...
(Date:10/13/2017)... ... ... Apple Rehab Shelton Lakes , which specializes in the delivery of ... part of a disaster drill on October 3rd. , Apple Rehab participated with the ... as well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). The ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional ... action towards gender equality at their inaugural Summit in New York City in June. ... a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... , ... Talented host, actor Rob Lowe, is introducing a ... episode of "Success Files," which is an award-winning educational program broadcasted on PBS ... in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve in ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and the ... published author, William Nowers. Captain Nowers and his wife, Millie, have six children, ... in the Navy. Following his career as a naval aviator and carrier pilot, ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... Israel and NEW YORK , Sept. 27, ... with mobile health and big data solutions, today announced that its MyDario ... Please check your local TV listings for when The Dr. Oz Show ... ... season this month. ...
(Date:9/22/2017)... 22, 2017 AVACEN Medical (AVACEN) announced that ... successfully helping those with the widespread pain associated with ... Amanda in Essex, England commented, ... hair, experiencing no sleep at all, tremendous pain, with ... cannot recommend [the AVACEN 100] enough, how this has ...
(Date:9/13/2017)... Sept. 13, 2017   OrthoAtlanta has been named ... Football Host Committee (AFHC) for the 2018 College Football Playoff ... 2018, at Mercedes-Benz Stadium in Atlanta, Georgia ... AFHC "I,m In" campaign, participating in many activities leading up ... ...
Breaking Medicine Technology: