Navigation Links
Scientists Tout New Prostate Cancer Test

Oregon scientists say a simple test can identify men at high risk of life-threatening prostate cancer even after a biopsy finds no signs of it//. The key, researchers say, is "PSA density," which compares the size of a man's prostate with his levels of a cancer-related protein called prostate-specific antigen.

Men with the highest PSA densities were much more likely to later be diagnosed with aggressive cancers than men with lower scores in an Oregon study, even though both groups had clean prostate biopsies.

If it survives scientific review, it could help save the lives of men with serious cancers and avoid repeated biopsies in others.

"It's that 1-in-10 men that do have a life-threatening cancer that we wanted to identify," said Dr. Mark Garzotto, an Oregon Health & Science University Cancer Institute researcher, who recently presented the study at a cancer conference in Florida.

Prostate cancer will kill about 27,000 U.S. men this year. Doctors usually check for tumors with a prostate biopsy, which uses needles to gather cells from the gland.

More than a million U.S. men get prostate biopsies each year. The tests find more than 200,000 tumors, meaning many cancer-free men get unneeded biopsies.

Studies estimate that the test fails to find the tumor in 20 percent to 33 percent of men who have one, usually because the needles sample only bits of the gland.

"With less than 1 percent of the prostate sampled, we're trying to get the pathologist to tell us if the guy has cancer or not, which is an impossible task," said Garzotto. So doctors recommend second biopsies a few months after a clean test.

To narrow the need for repeat tests, Garzotto and co-workers studied 511 patients at the Veterans Affairs Medical Center, where he works. All the men had clear initial prostate biopsies. But 112 were later found to have cancer, 52 of them aggressive tumors that can be deadly.

The scientists found that "PSA density, by itself, was the best discriminator between guys in the high-risk group and the guys in the low-risk group," Garzotto said.

By 2 years after their clean biopsy, 23 percent of the men in the high-risk group had aggressive cancer compared with 4 percent of low-risk men, Garzotto said.

At four years, the rate was 36 percent in the high-risk group and 9 percent in the other.

"I feel more comfortable now about recommending repeat biopsies to this (high-risk) group," he said.

Another simple test may identify which men with advanced prostate cancer have the worst outlook, according to a different OHSU study presented at the Florida conference.

Dr. Tomasz Beer found that among men with advanced cancer, those with the highest level of C-reactive protein died significantly sooner than men with lower levels.

C-reactive protein is a sign of inflammation, which doctors increasingly think is "associated with cancer progression and cancer resistance to treatment," Beer said.

Source-Bio-Bio Technology
'"/>




Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. Scientists found ancient Human Germ Killer
3. Scientists locate key hormone involved in appetite control
4. Scientists open the book of life
5. Scientists review SARS
6. Scientists crack dengue fever puzzle
7. Scientists push to lower hidden sodium in food
8. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
9. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
10. Scientists reveal the secrets of sarcasm
11. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... agency serving communities in the greater Dallas, Miami, and Raleigh regions, is organizing ... fighting to overcome a rare and deadly chromosome abnormality. , After struggling since ...
(Date:10/13/2017)... ... October 13, 2017 , ... The International ... promote standards of excellence for the field of eating disorders, announces the opening ... 25, 2018 in Orlando, Florida at the Omni Resort at ChampionsGate. ...
(Date:10/13/2017)... ... , ... Many families have long-term insurance that covers care for a family ... for care if the client has a cognitive impairment diagnosis. , “What this ... often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, owner ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... giving viewers the lowdown on sciatica in a new episode of "Success Files," ... on current events and innovation and investigates each subject in-depth with passion and ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and San Francisco dentists, ... cutting-edge Oventus O2Vent technology. As many as 18 million Americans are estimated to ... breathing. Oral appliances can offer significant relief to about 75 percent of people ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... --  West Pharmaceutical Services, Inc. (NYSE: WST), a ... today shared the results of a study highlighting the ... administration of polio vaccines. The study results were presented ... by Dr. Ondrej Mach , Clinical Trials and ... and recently published in the journal Vaccine. i ...
(Date:10/4/2017)... SEOUL, South Korea , Oct. 4, 2017 /PRNewswire/ ... launched its next-generation CPR training aide "cprCUBE" on Kickstarter. ... of chest compression during cardiac arrests with better efficiency ... patient-mannequins. It also offers real-time feedback on efficacy of ... The crowdfunding campaign has a goal to raise ...
(Date:10/2/2017)... 2, 2017 Diplomat Pharmacy, Inc. (NYSE: ... and Consulting, LLC , and named its founder as ... in Tennessee , will operate under ... EnvoyHealth,s service offerings for health care partners to include ... "In an interoperable world, technology delivers ...
Breaking Medicine Technology: