Navigation Links
Scientists Genetically Engineer Tomatoes With Enhanced Folate Content

Leafy greens and beans aren't the only foods that pack a punch of folate, the vitamin essential for a healthy// start to pregnancy.

Researchers now have used genetic engineering--manipulating an organism's genes--to make tomatoes with a full day's worth of the nutrient in a single serving. The scientists published their results in this week's online edition of the journal PNAS, Proceedings of the National Academy of Sciences.

"This could potentially be beneficial worldwide," said Andrew Hanson, a plant biochemist at the University of Florida at Gainesville who developed the tomato along with colleague Jesse Gregory. "Now that we've shown it works in tomatoes, we can work on applying it to cereals and crops for less developed countries where folate deficiencies are a very serious problem."

Folate is one of the most vital nutrients for the human body's growth and development, which is why folate-rich diets are typically suggested for women planning a pregnancy or who are pregnant. Without it, cell division would not be possible because the nutrient plays an essential role in both the production of nucleotides--the building blocks of DNA--and many other essential metabolic processes.

Deficiencies of the nutrient have been linked to birth defects, slow growth rates and other developmental problems in children, as well as numerous health issues in adults, such as anemia.

"Folate deficiency is a major nutritional deficiency, especially in the developing world," said Parag Chitnis, program director in the National Science Foundation's Division of Molecular and Cellular Biosciences, which funded the research. "This research provides the proof-of-concept for the natural addition of folate to diet through enhancement of the folate content of fruits and vegetables."

The vitamin is commonly found in leafy green vegetables like spinach, but few people eat enough produce to get the suggested amount of folate. So, in 1998 , the Food and Drug Administration made it mandatory that many grain productssuch as rice, flour and cornmeal be enriched with a synthetic form of folate known as folic acid.

Folate deficiencies remain a problem in many underdeveloped countries, however, where adding folic acid is impractical or simply too expensive.

"There are even folate deficiency issues in Europe, where addition of folic acid to foods has not been very widely practiced," Gregory said. "Theoretically, you could bypass this whole problem by ensuring that the folate is already present in the food."

Will doctors be recommending a healthy dose of salsa for would-be pregnant women anytime soon? Probably not, the researchers say.

"It can take years to get a genetically-engineered food plant approved by the FDA," Hanson said. "But before that is even a question, there are many more studies to be done--including a better look at how the overall product is affected by this alteration."

And there is another hurdle the researchers must clear. Boosting the production of folate in tomatoes involved increasing the level of another chemical in the plant, pteridine. Little is known about this chemical, which is found in virtually all fruits and vegetables.


Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. Scientists found ancient Human Germ Killer
3. Scientists locate key hormone involved in appetite control
4. Scientists open the book of life
5. Scientists review SARS
6. Scientists crack dengue fever puzzle
7. Scientists push to lower hidden sodium in food
8. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
9. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
10. Scientists reveal the secrets of sarcasm
11. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
Post Your Comments:

(Date:11/26/2015)... ... ... Inevitably when people think Thanksgiving, they also think Holiday sales and start ... and Cyber Monday massage chair sales to receive the best pricing on ... find the best massage chair deals, they can see all of the coupons in ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... Travel Representative. As a franchise owner, Somu now offers travelers, value and care ... wedding packages, private cruise sales, as well as, cabin upgrades and special amenities ...
(Date:11/26/2015)... ... 26, 2015 , ... Jobs in hospital medical laboratories and in the imaging ... staffing agency Aureus Medical Group . These fields, as well as ... searching for healthcare jobs through the company’s website, , The leading ...
(Date:11/26/2015)... (PRWEB) , ... November 26, 2015 , ... ... second medical opinion process, participated in the 61st annual Employee Benefits Conference. The ... and took place Sunday, November 8th through Wednesday, November 11th, 2015. The conference ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... and wellness consultation, has collaborated with Women’s Web – an online resource ... on topics on mental and emotional well-being relationship, life balance, stress, professional ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... -- Research and Markets ( ) has ... Horizons and Growth Strategies in the Italian Therapeutic ... Forecasts, Competitive Intelligence, Emerging Opportunities" report to ... --> This new 247-page report provides ... monitoring market, including emerging tests, technologies, instrumentation, sales ...
(Date:11/25/2015)...  Amgen (NASDAQ: AMGN ) today announced the ... the United States (U.S.) Food and ... to Humira ® (adalimumab). Amgen believes this submission ... FDA and represents Amgen,s first BLA submission using the ... M.D., executive vice president of Research and Development at ...
(Date:11/25/2015)... , Nov. 25, 2015  ARKRAY USA ... continues to provide evidence demonstrating the accuracy of its ... Congress on Insulin Resistance, Diabetes and Cardiovascular Disease in ... both the Company,s GLUCOCARD ® 01 meter and ... accuracy requirements. The ability to accurately measure glucose levels ...
Breaking Medicine Technology: