Navigation Links
Scientists Find Single Circuit Channeling Depression in Rats

Scientists and doctors long baffled by the multiple causes and brain processes for depression may now have a single "holy grail" brain pathway to focus on for treatment, according to a new research study released Thursday.

Studying the brains of rats, researchers at the Stanford University School of Medicine have discovered a single brain circuit that appears to funnel all the mechanisms and treatments of depression.

Depression-related behavior is manifested in changes in electrical signals moving through the circuit, according to the study released on the journal Science's website.

Karl Deisseroth, a professor of bioengineering and of psychiatry and behavioral sciences, said the circuit can help explain why there can be many causes and treatments of depression.

"It also helps us understand conceptually how something that seems as hard to get traction on as depression can have a really quantitative, concrete basis," he said in a summary of the study.

Deisseroth led a research team to see if they could demonstrate how malfunctions in brain circuitry could be at the root of depression.

They studied the electrical activity of still-active slices of the hippocampus section of rat brains treated with flourescent dye, using high-speed high-resolution cameras to record activity in brain neurons in real time.

According to Deisseroth, rat brains show similar depression symptoms to human ones and react to anti-depression medicines in the same way.

The testing showed that an alteration in electrical activity flow through the brain could be readjusted with the use of human drugs against depression -- suggesting the existence of a specific circuit for the condition.

According to Deisseroth, the discovery of the single circuit for depression could lead to methods doctors could use to better diagnose and quantify the problem in their human patients.
"The holy grail of psychiatry is to try to find final common pathways that can make sense of how genes and life experiences end up with the same result," he said.

"And the same goes for medications. There are many treatments that act in fundamentally different ways -- how do we make sense of all that complexity?"


'"/>




Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. Scientists found ancient Human Germ Killer
3. Scientists locate key hormone involved in appetite control
4. Scientists open the book of life
5. Scientists review SARS
6. Scientists crack dengue fever puzzle
7. Scientists push to lower hidden sodium in food
8. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
9. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
10. Scientists reveal the secrets of sarcasm
11. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of ... too high can result in disappointment, perhaps even self-loathing. However, those who set the ... Research from PsychTests.com reveals that behind the tendency to set low expectations ...
(Date:6/24/2016)... ... , ... Marcy was in a crisis. Her son James, eight, was out of control. Prone ... physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If ... at my other children and say he was going to kill them. If we ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is ... Road To Recovery® program to drive cancer patients to and from their cancer treatments. ... the highest quality of life and ongoing independence. Getting to and from medical ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty ... Barry M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... and the most handsome men, look naturally attractive. Plastic surgery should be invisible.” ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) ... held on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, ... dedicated to helping service members that have been wounded in battle and their families. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Medical Market Analysis 2016 - Forecast to 2022" report ... The report contains up to date financial data derived from ... of major trends with potential impact on the market during ... market segmentation which comprises of sub markets, regional and country ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
Breaking Medicine Technology: