Navigation Links
Scientists Find Single Circuit Channeling Depression in Rats

Scientists and doctors long baffled by the multiple causes and brain processes for depression may now have a single "holy grail" brain pathway to focus on for treatment, according to a new research study released Thursday.

Studying the brains of rats, researchers at the Stanford University School of Medicine have discovered a single brain circuit that appears to funnel all the mechanisms and treatments of depression.

Depression-related behavior is manifested in changes in electrical signals moving through the circuit, according to the study released on the journal Science's website.

Karl Deisseroth, a professor of bioengineering and of psychiatry and behavioral sciences, said the circuit can help explain why there can be many causes and treatments of depression.

"It also helps us understand conceptually how something that seems as hard to get traction on as depression can have a really quantitative, concrete basis," he said in a summary of the study.

Deisseroth led a research team to see if they could demonstrate how malfunctions in brain circuitry could be at the root of depression.

They studied the electrical activity of still-active slices of the hippocampus section of rat brains treated with flourescent dye, using high-speed high-resolution cameras to record activity in brain neurons in real time.

According to Deisseroth, rat brains show similar depression symptoms to human ones and react to anti-depression medicines in the same way.

The testing showed that an alteration in electrical activity flow through the brain could be readjusted with the use of human drugs against depression -- suggesting the existence of a specific circuit for the condition.

According to Deisseroth, the discovery of the single circuit for depression could lead to methods doctors could use to better diagnose and quantify the problem in their human patients.
"The holy grail of psychiatry is to try to find final common pathways that can make sense of how genes and life experiences end up with the same result," he said.

"And the same goes for medications. There are many treatments that act in fundamentally different ways -- how do we make sense of all that complexity?"


Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. Scientists found ancient Human Germ Killer
3. Scientists locate key hormone involved in appetite control
4. Scientists open the book of life
5. Scientists review SARS
6. Scientists crack dengue fever puzzle
7. Scientists push to lower hidden sodium in food
8. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
9. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
10. Scientists reveal the secrets of sarcasm
11. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
Post Your Comments:

(Date:11/26/2015)... (PRWEB) , ... November 26, 2015 , ... Indosoft Inc., ... inclusion of an application server to improve system efficiency and reliability. , The new ... many of these standards, the system avoids locking itself into a specific piece of ...
(Date:11/25/2015)... ... November 25, 2015 , ... Medical ... once again for its stellar workplace culture with the company’s Cincinnati office being ... Medical Solutions’ Cincinnati office was named a finalist in Cincinnati Business Courier’s 13th ...
(Date:11/25/2015)... ... November 25, 2015 , ... For the first time, Vitalalert is ... One Beat ” campaign. The partnership between the two groups began in 2014 with ... International’s cause. , MAP International was founded in 1954 and is an international Christian-based ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... and athletic programs, launches new Wimbledon Athletics Facebook page to educate ... athletes for unsuspected cardiac abnormalities. About 2,000 people under the age of 25 ...
(Date:11/25/2015)... Calif. (PRWEB) , ... November 25, 2015 , ... Beddit® ... and Beddit Classic sleep tracking systems. The new app features a more intuitive SleepScore™ ... and understand how well you slept. The SleepScore is created by a proprietary algorithm. ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... announced the addition of the  "2016 ... the European Therapeutic Drug Monitoring (TDM) ... Competitive Intelligence, Emerging Opportunities"  report to ... ) has announced the addition of ...
(Date:11/26/2015)... , Nov. 26, 2015 Research ... addition of the "2016 Future Horizons and ... (TDM) Market: Supplier Shares, Country Segment Forecasts, Competitive ... --> --> ... analysis of the Italian therapeutic drug monitoring market, ...
(Date:11/25/2015)... , Nov. 25, 2015 ... the addition of the "Global Brain ... their offering. --> ) ... "Global Brain Monitoring Devices Market 2015-2019" ... Research and Markets ( ) has ...
Breaking Medicine Technology: