Navigation Links
Scientists Find Potential Weakness In Plague Germ

The germ that caused the plague epidemic that ravaged medieval Europe has a weakness that could help make a particularly dangerous form easier to treat//, according to a study published on Thursday.

A bacterium known as Yersinia pestis causes both bubonic plague, the dreaded Black Death spread when people are bitten by an infected flea, and pneumonic plague, spread from one person to another through coughing or sneezing.

There are periodic natural outbreaks of pneumonic plague like one that started in 2005 in the Democratic Republic of Congo. There also is acute concern terrorists could harness the bacterium as an airborne germ warfare agent to spread pneumonic plague.

Writing in the journal Science, scientists at Washington University School of Medicine in St. Louis said experiments with mice showed that the onslaught of the bacterium slows markedly when the germ cannot use a key protein.

Pneumonic plague can kill a person in three or four days after infection. Antibiotics can beat the bacterium, but by the time the infection becomes apparent the disease has progressed so far that it may be too late for them to do any good.

"It leaves a very narrow window of time that you could administer antibiotics and hope for good results," said William Goldman, the study's senior author.

Goldman said it might be possible to develop a drug that could slow progression of the disease so antibiotics can work.

Plague is uncommon now, but worth studying, Goldman said.

"It's easy to grow this bacterium. So I think there is a general concern that if someone really wanted to design a bioweapon, this is a candidate," said Goldman, professor of molecular microbiology at Washington University.

TWO-PHASE DISEASE
The researchers developed a mouse model of the disease that mimicked human pneumonic plague.

It is a two-phase disease that begins with bacteria multiplying rapidly in the lung
'"/>




Page: 1 2

Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. Scientists found ancient Human Germ Killer
3. Scientists locate key hormone involved in appetite control
4. Scientists open the book of life
5. Scientists review SARS
6. Scientists crack dengue fever puzzle
7. Scientists push to lower hidden sodium in food
8. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
9. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
10. Scientists reveal the secrets of sarcasm
11. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists Find Potential Weakness Plague Germ

(Date:10/22/2014)... only 24 hours in a day, that doesn’t seem to be ... their busy schedules for exercise and fitness. Fortunately, one does not ... shape. Here are five ways you can reach your fitness and ... Commute , Consider riding a bike or taking the bus or ... If you must use your car to get to work, start ...
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. 21, 2014 (HealthDay ... be showing a genetic propensity for obesity as toddlers, a ... linked to increased body fat, but the same genes in ... researchers said. At 1 year, kids with these genes ... however, these genes were linked to excessive weight gain, the ...
(Date:10/22/2014)... Maureen Salamon HealthDay Reporter ... part of conventional in vitro fertilization (IVF) -- the incubation ... place in a device inside the vagina, new research suggests. ... the device, called an INVOcell, might sharply cut costs for ... the technology more accessible to those who don,t live near ...
(Date:10/20/2014)... 20, 2014 The newly updated Worldwide ... of thousands of facts, figures and forecasts on the ... medical sector forecast categories the Worldwide Medical Market ... and national views on the worldwide medical market to ... report gives you data for 2010-2019, covering each country ...
(Date:10/20/2014)... ASCNYC (ascnyc.org) is a New ... Yorkers living with HIV/AIDS and other chronic conditions ... and self-sufficiency. Each year, ASCNYC spotlights selected “Positive ... their tireless efforts. , Savills Studley ... been selected as this year’s honoree for sharing ...
Breaking Medicine News(10 mins):Health News:HealthGuideMD Presents Ways to Improve Your Exercise and Fitness 2Health News:Tall, Heavy 1-Year-Olds May Be at Risk for Obesity Later, Study Finds 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 4Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 2Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 3Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 4Health News:Savills Studley's Marc Shapses To Be Honored as 2014 "Positive Changemaker" by ASCNYC 2Health News:Savills Studley's Marc Shapses To Be Honored as 2014 "Positive Changemaker" by ASCNYC 3
... which claim to use subtle energy to stimulate the ... the intensity of pain in a number of conditions, ... in dementia, over and above what standard treatments can ... Jain, from the UCLA Division of Cancer Prevention and ...
... FRANCISCO, Oct. 29 VIA Pharmaceuticals, Inc. (Nasdaq: ... the development of compounds for the treatment of ... Rebecca Taub, Senior Vice President Research & Development ... Targeting Cardiometabolic Disease", and will discuss the Company,s ...
... employers to take heed , THURSDAY, Oct. 29 (HealthDay News) ... it might get worse -- at least for a while. ... report that stress levels peak when people reach their early ... age. , That,s not necessarily good news, either: Work-related ...
... ... Business Journal’s 11th annual award for the health care company category , ... Pompano Beach, FL (PRWEB) October 29, ... Health Care Award in the health care company category. The South Florida Business ...
... found that rheumatoid arthritis (RA) patients did not experience ... after starting anti-tumor necrosis factor (TNF) therapy. The ... Karolinska University Hospital in Stockholm, Sweden assessed the short-term ... therapies: infliximab, adalimumab, and etanercept. Details of the ...
... ... stereotypes , ... Arlington, VA (PRWEB) October 28, 2009 -- As Halloween approaches, the National Alliance ... costumes and other seasonal attractions that feature inaccurate and offensive stereotypes regarding those with ...
Cached Medicine News:Health News:Biofield therapies: Helpful or full of hype? 2Health News:VIA Pharmaceuticals Featured at Cambridge Healthtech Institute Discovery on Target 2009 Conference 2Health News:VIA Pharmaceuticals Featured at Cambridge Healthtech Institute Discovery on Target 2009 Conference 3Health News:VIA Pharmaceuticals Featured at Cambridge Healthtech Institute Discovery on Target 2009 Conference 4Health News:VIA Pharmaceuticals Featured at Cambridge Healthtech Institute Discovery on Target 2009 Conference 5Health News:After Age 55, Workplace Stress Seems to Decline 2Health News:American Diabetes Wholesale Wins 2009 Excellence In Health Care Award from South Florida Business Journal 2Health News:Anti-tumor necrosis factor treatment does not increase cancer Risk in RA patients 2Health News:NAMI Issues "Stigma Alert" Over Inaccurate and Offensive Halloween Costumes, Attractions 2Health News:NAMI Issues "Stigma Alert" Over Inaccurate and Offensive Halloween Costumes, Attractions 3
(Date:10/22/2014)... 2014  Early symptoms of diabetic eye and ... new technology, coupled with yearly, comprehensive eye exams, ... detection of eye diseases, including those associated with ... left untreated, these diseases can potentially lead to ... Recently, optometric researchers have deployed a new tool ...
(Date:10/22/2014)... 22, 2014 InVivo Therapeutics Holdings Corp. (OTCQB: ... is revolutionizing spinal cord injury (SCI) treatment with their ... outperform in tissue regrowth in the spinal cord area ... an FDA approved polymer, the scaffold ultimately breaks down ... the human body. NVIV has recently attracted significant investor ...
(Date:10/22/2014)... 2014 Provectus Biopharmaceuticals, Inc. (NYSEMKT: PVCT) specializes ... investigational drug for cancer, is designed for injection into ... Its oncology focus is on melanoma, breast cancer and ... trials of PV-10 as a therapy for metastatic melanoma, ... dermatitis and psoriasis. This summer, the ...
Breaking Medicine Technology:Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 2Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 3InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 2InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 3Provectus Biopharmaceuticals Looks at the Asian Markets: Analyst Coverage by Small Cap Traders 2
... 7, 2011  Tethys Bioscience has entered into an agreement ... employers measurably flatten the trajectory of their healthcare trends ... their employee populations. The agreement allows ACAP Health to ... as a component of its disease intervention programs. The ...
... 2011 Ampio Pharmaceuticals, Inc. (NASDAQ: AMPE ... and develops new uses for previously approved drugs and ... of the granting of a European patent with broad ... diketopiperazine which is the active ingredient of Ampion™.  The ...
Cached Medicine Technology:Tethys Bioscience and ACAP Health Consulting Partner to Help Employers Prevent Diabetes 2Tethys Bioscience and ACAP Health Consulting Partner to Help Employers Prevent Diabetes 3Ampio Pharmaceuticals Awarded European Patent that Strengthens Intellectual Property Protection for its key drug Ampion™ 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: