Navigation Links
Scientists Enlist Worms to Discover New Therapies for Huntington’s Diseas

Scientists from UAH are working with the U.S army to find clues that may help to build therapies for// Huntington’s disease.

Lead researcher Dr. Lynn Boyd, an associate professor of biology at UAH has enlisted the help of an army of worms to find out what effect certain enzymes will have, on the clusters of amino acids associated with Huntington’s disease.

The experiment is being carried out at the Army's Primary Standards Laboratory at Redstone Arsenal.

While it is not known if these clumps are good or not (scientists think it might be a way of the cell removing bad amino acids out of the way), the team has discovered some enzymes which make the clumps bigger, and some which make it smaller.

The worms come into the picture when the scientists attach glowing proteins derived from jellyfish to certain enzymes, which are then tagged onto the chromosomes of the worms. They inject the dye-tagged genetic material into the worms before they are zapped by powerful radiation.

At just the right level of radiation, the DNA strands in the worms' unfertilized eggs snap and the dye-tagged material slips into the chromosomes.

The glowing protein is then reproduced in the worm's offspring. If the target material concentrates in clumps it creates glowing spots, giving the UAH researchers a tool for tracking what happens when specific enzymes are suppressed.

The UAH team hoped to tag individual strains of worms for seven specific enzymes.

Using human cells grown in a culture, Boyd found that suppressing the human enzymes that corresponded to the worm enzymes had the same effects on polyglutamine aggregates.

The researchers hope the findings will contribute to therapies aimed at treating Huntington’s disease.

Source-Newswise
AN
'"/>




Page: 1

Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. Scientists found ancient Human Germ Killer
3. Scientists locate key hormone involved in appetite control
4. Scientists open the book of life
5. Scientists review SARS
6. Scientists crack dengue fever puzzle
7. Scientists push to lower hidden sodium in food
8. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
9. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
10. Scientists reveal the secrets of sarcasm
11. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2017)... St. Louis, MO (PRWEB) , ... August 22, 2017 , ... ... and career fairs to help healthcare employers connect with physicians and advanced practitioners like ... of virtual career fairs in August through November of this year. The ...
(Date:8/21/2017)... Aliso Viejo, CA (PRWEB) , ... August 21, 2017 , ... ... Pixel Film Studios. Editors can quickly and easily add washed color grades to ... an image. The LUT changes every pixel’s color to the corresponding color indicated by ...
(Date:8/21/2017)... , ... August 21, 2017 , ... ... recognized community involvement program serving the people of Michigan. The new initiative fundraises ... 120 years at the very forefront of animal protection and welfare by addressing ...
(Date:8/21/2017)... ... 2017 , ... San Diego physician and surgeon Dr. James Veltmeyer, author of ... candidacy for the 52nd Congressional District currently held by Representative Scott Peters. , ... country at age eleven after suffering homelessness and hardship in a distant land, I ...
(Date:8/20/2017)... (PRWEB) , ... August 20, 2017 , ... ... the HIPAA ComplyPAK™ Compliance Management System has assisted multiple clients in ... Certified Public Accountants, Service Organization Control Level 2 (AICPA SOC Level 2), and ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... CaryRx, a next-generation full-service pharmacy, has announced the ... in the Washington D.C. metropolitan area. ... delivery of medications through the convenience of its patient-friendly mobile ... within one hour to any location in D.C. ... invaluable service to Washington D.C. ," says ...
(Date:7/28/2017)... Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today ... June 30, 2017, and updated its financial outlook for ... For the fiscal third quarter, Hill-Rom reported earnings of ... share in the prior-year period. These results reflect after-tax ... share primarily related to the non-cash write-down of assets ...
(Date:7/26/2017)... Aesthetics, a leading medical aesthetic clinic in Singapore ... skin conditions from the inside. The natural process of ... skin becomes more transparent due to the thinning of the epidermis. Over ... the sun contributes to aging skin, causing age spots and other ... ...
Breaking Medicine Technology: