Navigation Links
Scientists Enlist Worms to Discover New Therapies for Huntington’s Diseas

Scientists from UAH are working with the U.S army to find clues that may help to build therapies for// Huntington’s disease.

Lead researcher Dr. Lynn Boyd, an associate professor of biology at UAH has enlisted the help of an army of worms to find out what effect certain enzymes will have, on the clusters of amino acids associated with Huntington’s disease.

The experiment is being carried out at the Army's Primary Standards Laboratory at Redstone Arsenal.

While it is not known if these clumps are good or not (scientists think it might be a way of the cell removing bad amino acids out of the way), the team has discovered some enzymes which make the clumps bigger, and some which make it smaller.

The worms come into the picture when the scientists attach glowing proteins derived from jellyfish to certain enzymes, which are then tagged onto the chromosomes of the worms. They inject the dye-tagged genetic material into the worms before they are zapped by powerful radiation.

At just the right level of radiation, the DNA strands in the worms' unfertilized eggs snap and the dye-tagged material slips into the chromosomes.

The glowing protein is then reproduced in the worm's offspring. If the target material concentrates in clumps it creates glowing spots, giving the UAH researchers a tool for tracking what happens when specific enzymes are suppressed.

The UAH team hoped to tag individual strains of worms for seven specific enzymes.

Using human cells grown in a culture, Boyd found that suppressing the human enzymes that corresponded to the worm enzymes had the same effects on polyglutamine aggregates.

The researchers hope the findings will contribute to therapies aimed at treating Huntington’s disease.

Source-Newswise
AN
'"/>




Page: 1

Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. Scientists found ancient Human Germ Killer
3. Scientists locate key hormone involved in appetite control
4. Scientists open the book of life
5. Scientists review SARS
6. Scientists crack dengue fever puzzle
7. Scientists push to lower hidden sodium in food
8. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
9. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
10. Scientists reveal the secrets of sarcasm
11. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified ... be personalized through a fitness app. The fitness app plans to fix the two major ... only offer a one size fits all type program , They don’t eliminate ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Austin residents ... the American College of Mohs Surgery and to Dr. Russell Peckham for medical and ... highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the ... Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , “We ... new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of ... award to iHire in recognition of their exemplary accomplishments in worksite health promotion. , ... Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Dehaier Medical Systems Ltd. (NASDAQ: ... markets and sells medical devices and wearable sleep respiratory ... strategic cooperation agreement with Hongyuan Supply Chain Management Co., ... June 20, 2016, to develop Dehaier,s new Internet medical ... Dehaier will leverage Hongyuan Supply Chain,s sales platform to ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... "The World Market for Companion Diagnostic Tests" report to ... World Market for Companion Diagnostics The World ... diagnostic and personalized medicine diagnostics. Market analysis in the report ... Diagnostics Test Market (In Vitro Diagnostic Kits) by Region (N. ...
(Date:6/24/2016)... --  Pulmatrix, Inc ., (NASDAQ: PULM ), ... today that it was added to the Russell Microcap ... set of U.S. and global equity indexes on June ... for Pulmatrix," said Chief Executive Officer Robert Clarke ... in developing drugs for crucial unmet medical needs, and ...
Breaking Medicine Technology: