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Scientists Create Live Birth Using Artificial Sperms Produced In Vitro

Scientists hoping to find a solution for male infertility have in an experiment for the first time ever, produced and used artificial sperms to create a living being// (mice).

Professor Karim Nayernia and team, from Georg-August University, Gottingen, Germany, have created artificial sperm in a lab from the mouse embryonic stem cells. Professor Nayernia, who has now moved to the Newcastle-Durham NHS Institute for Stem Cell Biology and Regenerative Medicine this month, had earlier said, "For the first time we have been able to produce sperm in vitro, and use these sperm to fertilise eggs and get live births in animals."

The scientists have fertilised mouse eggs with sperm grown from embryonic stem (ES) cells to produce seven pups, thereby proving that working reproductive cells can be prepared in the laboratory. The experiment and the successful births have now provided the most conclusive evidence so far on the possibility of eventually using stem cells to treat infertile men who can make no sperm of their own.

Previous experiments that were conducted had suggested that the artificial eggs could be made from female embryos, which had raised hopes for infertile women, although no offspring were born. The scientists hope that in the longer term, it might be possible to create sperm from female stem cells, and eggs from male ones, which could allow homosexual couples to have children bearing the genes of both parents. In theory, the scientists propose that a single person might even provide both the eggs and sperm needed to create an embryo.

They did however clarify that the creation of 'male egg' and 'female sperm', could however, face many a difficult barriers, as embryos generally require genetic material from both, mother and father so as to develop normally. The researchers hoped that the immediate benefit of the research would be a deeper more complex understanding on the formation of the mature sperm, and improved
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