Navigation Links
Scientists Coax Nerve Fibers to Regrow After Spinal Cord Injury

nd nerve fibers, which may be why we have developed careful controls that tell cells to stop making new connections. The crowded central nervous system has ways to say ‘OK, we’re done’ to keep nerves from sprouting willy-nilly and making inappropriate connections. But in gaining the ability to crowd nerves close together, we have given up flexibility - the ability to heal after injury.”

“If you sever your finger, it can be surgically reattached, and nerve fibers typically grow back so that you can use your finger again,” says Schnaar. “In contrast, the injured brain and spinal cord are rocky terrain for nerve fiber growth,” he says. “Finding ways to smooth that road might help the nerve fibers to regrow.”

Several molecules in the spinal cord are known to stop nerve fibers from growing. Schnaar refers to these molecules as axon regeneration inhibitors, or simply ARIs.

“Treatments that eliminate ARIs might allow the nerve ends to regain their natural regenerative abilities as they do in the periphery and improve recovery,” says Schnaar.

The researchers looked at the boundary between the spinal cord and the periphery to see if they could coax a nerve end to grow out of the inhibitory spinal cord into a more permissive environment that contains fewer ARIs. They chose to mimic the injury commonly seen in motorcycle accidents, called brachial plexus avulsion, because it involves nerves at the boundary between the spinal cord and periphery.

The researchers surgically severed nerves that normally extend from the spinal cord to the shoulder of anesthetized rats. They then transplanted a nerve from the hind leg of the same animal into the spinal cord to reconnect the injured nerve ends.

To coax the injured nerve ends to grow fibers and connect to the transplanted nerve, they used an implanted pump to bathe the area with one of three different enzymes known to destroy ARIs. Four weeks after transplantati
'"/>




Page: 1 2 3 4

Related medicine news :

1. Scientists plan human cloning clinic in the United States
2. Scientists found ancient Human Germ Killer
3. Scientists locate key hormone involved in appetite control
4. Scientists open the book of life
5. Scientists review SARS
6. Scientists crack dengue fever puzzle
7. Scientists push to lower hidden sodium in food
8. Indian Scientists Make Wide-Ranging Analysis And Annotation Of X Chromosome
9. Scientists have found effective brain regions for deep brain stimulation for Parkinson’s
10. Scientists reveal the secrets of sarcasm
11. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists Coax Nerve Fibers Regrow After Spinal Cord Injury

(Date:8/3/2015)... Spring, MD (PRWEB) , ... August 03, 2015 , ... ... the addition of a new associate podiatrist, creating the largest medical practice in the ... foot and ankle medicine. FASMA operates 21 locations with 33 doctors. , Dr. Hetal ...
(Date:8/2/2015)... ... August 03, 2015 , ... ... attending and exhibiting at the Association for Healthcare Documentation Integrity’s (AHDI) conference being ... are pleased for the opportunity the AHDI conference provides us to interact with ...
(Date:8/1/2015)... ... August 02, 2015 , ... AlignLife Office ... help the continuity of care for patients at this natural health care center in ... Clinic Director Mary Heal said. "Heather's role is vital to our approach because we ...
(Date:8/1/2015)... ... 2015 , ... Calvary Hospital today announced that it is embarking on a ... is to bring this Torah – dating from 1880 – back to kosher status, ... , Scroll No. 515, from the town of Taus-Domazlice, is on permanent loan ...
(Date:8/1/2015)... ... August 01, 2015 , ... Lume Wellness creators Alex, ... free to download on the Apple AppStore. , The app is designed to ... thus acting as a tool to view personal health and use this information for ...
Breaking Medicine News(10 mins):Health News:Leading Foot and Ankle Medical Practice Adds Three New Podiatrists 2Health News:Leading Foot and Ankle Medical Practice Adds Three New Podiatrists 3Health News:Leading Foot and Ankle Medical Practice Adds Three New Podiatrists 4Health News:Career Step to Exhibit at AHDI Conference in Alexandria, Virginia on August 7-8 2Health News:New Patient Advocate Enhances Natural Health Care 2Health News:Calvary Hospital Announces Plans to Restore Historic Torah 2Health News:Calvary Hospital Announces Plans to Restore Historic Torah 3Health News:Lume Wellness Launches Health and Fitness Tracker iPhone App 2
... Reporter , TUESDAY, April 19 (HealthDay News) -- The first ... disease could double the number of Americans defined as having ... Alzheimer,s Association and the U.S. National Institute of Aging, differ ... been in use since 1984. First, Alzheimer,s is ...
... , TUESDAY, April 19 (HealthDay News) -- Minority ... more likely to die in early childhood than whites, a ... nearly 20,000 black, Hispanic and white infants born with congenital ... Overall, black infants were 32 percent more likely to die ...
... . FRANKFURT, Germany. It is a rare ... start experiencing vision impairments, which two to three years ... indication of a progressive destruction of brain cells. Later ... finally, failure of all motor abilities. In this last ...
... at the University of California, San Diego School of ... found in people may be useful as a future ... early and, in sufficient concentration, used as a treatment ... led by Richard Schwab, MD, assistant clinical professor of ...
... HealthDay Reporter , TUESDAY, April 19 (HealthDay News) -- About ... were going to get all of the recommended vaccinations, and ... immunizations, two new surveys find. Pediatricians and infectious disease ... about a supposed autism/MMR (measles, mumps, rubella) link -- ...
... 2011, Springer will publish Translational Behavioral Medicine: ... the Society of Behavioral Medicine. The journal will ... Evidence Implementation. Translational Behavioral Medicine ... online-first publication. Its aim is to engage, ...
Cached Medicine News:Health News: Alzheimer's Cases Could Double With New Guidelines: Expert 2Health News: Alzheimer's Cases Could Double With New Guidelines: Expert 3Health News:Minority Kids With Heart Defects More Likely to Die in Childhood 2Health News:Hope for children with rare genetic defect 2Health News:Hope for children with rare genetic defect 3Health News:A cancer marker and treatment in 1? 2Health News:A cancer marker and treatment in 1? 3Health News:Most Parents Vaccinate Kids, Trust Docs' Advice on Shots 2Health News:Most Parents Vaccinate Kids, Trust Docs' Advice on Shots 3Health News:Springer launches new journal, Translational Behavioral Medicine: Practice, Policy, Research 2
(Date:7/31/2015)...  Semler Scientific, Inc. (Nasdaq: SMLR ), a ... insurers and physician groups, today reported financial results for ... "In the second quarter of 2015, Semler reported ... 54%, quarter over quarter revenue growth of 8%, and ... FloChec® units of 18%," said Doug Murphy-Chutorian, M.D., chief ...
(Date:7/30/2015)... 30, 2015 Edwards Lifesciences Corporation (NYSE: EW ... and hemodynamic monitoring, today announced that Robert A. Ingram ... "Bob is an ardent champion for innovation in the ... have him on Edwards, board as we pursue our focused ... and CEO.  "Bob has provided a valuable perspective to our ...
(Date:7/30/2015)...  Tandem Diabetes Care®, Inc. (NASDAQ: TNDM ... the t:slim® and t:flex™ Insulin Pumps, today announced ... with Dexcom, Inc. to allow the integration of ... G5 and G6 continuous glucose monitoring ("CGM") systems. ... with Dexcom,s future CGM systems is an important ...
Breaking Medicine Technology:Semler Reports Second Quarter 2015 Financial Results 2Semler Reports Second Quarter 2015 Financial Results 3Semler Reports Second Quarter 2015 Financial Results 4Semler Reports Second Quarter 2015 Financial Results 5Semler Reports Second Quarter 2015 Financial Results 6Tandem Diabetes Care Announces Development Agreement with Dexcom for Integration of Future Generation CGM Systems 2Tandem Diabetes Care Announces Development Agreement with Dexcom for Integration of Future Generation CGM Systems 3
... FDA Regarding Possible Phase III Trial Based on Human Data ... ... Neupogen(R), RICHMOND, Va., July 10, 2008 Insmed Inc.,(Nasdaq: ... medical needs, today announced that it has demonstrated the,bioequivalence of INS-19, ...
... Sosei Group Corporation,("Sosei"; TSE Mothers Index: 4565), ... Japanese Phase III clinical trial for the,emergency contraceptive ... rights to the product in Japan from HRA ... evaluate the safety and prevented,pregnancy rate of SOH-075 ...
Cached Medicine Technology:Insmed Announces First Human Bioequivalence Data for a Follow-on Biologic by a U.S. Company 2Insmed Announces First Human Bioequivalence Data for a Follow-on Biologic by a U.S. Company 3Insmed Announces First Human Bioequivalence Data for a Follow-on Biologic by a U.S. Company 4Insmed Announces First Human Bioequivalence Data for a Follow-on Biologic by a U.S. Company 5Sosei Announces Completion of Phase III Trial for NorLevo(R) 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: