Navigation Links
Safety Of Heart Drug Questioned

Reports of increased incidence of kidney failure following use of the drug aprotinin, marketed as Trasylol, has prompted necessity for reconsidering the use of the drug in heart surgery patients.// The clotting drug is commonly used to prevent excessive bleeding in patients undergoing cardiac surgery.

It has now been found from the present study that Trasylol injected patients were twice as likely to develop kidney failure and suffer from heart disorders compared to controls who received other drugs. The results of the study can be found in the New England Journal of Medicine.

The U.S. Food and Drug Administration (FDA) approved the drug for use in 1993. The primary indication was to control the bleeding and reduce necessity of blood transfusion in patients who underwent open-heart surgery. The drug acts by blocking the function of enzymes that are involved in the clot dissolving process.

The drug manufacturer, Bayer AG, a German based concern in response has stated that the drug has been approved following demonstration of adequate safety level in trials conducted by the company itself. Drug regulatory boards in Canada, Europe, Australia and United States have been alerted regarding the above research.

Last week, concerns were raised regarding the use of Novoseven, a drug used for management of cerebral hemorrhages (primary indication is for treatment of hemophilia). Increased risk of heart attack, stroke and even death were reported with use of the drug.

The researchers examined the effect of Trasylol in nearly 4,374 cardiac surgery patients. The study participants were given either Trasylol or a placebo. At the end of the study, the incidence of kidney failure, requiring dialysis was twice as likely in patients who took Trasylol when compared to the control group. The risk of heart attack or heart failure was 55% greater amongst Trasylol users.

Although anesthesiologists and surge ons have been raising concerns regarding the use of the drug, it is for the first time that a comprehensive study regarding safety of Trasylol has been conducted. More studies are clearly indicated in the future to accurately predict the risk-benefit ratio of such dangerous blood-thinning drugs.


'"/>




Related medicine news :

1. New standards for Human Research Safety
2. Safety of soy under suspicion
3. The Safety Of Prenatal Ultrasounds Questioned
4. Report on the Safety and Effectiveness of Melatonin supplements
5. Monitoring Drug Safety
6. Safety Of Indian Sex Workers At Risk Due To Poor Condom Usage
7. Race Was Used To Determine Safety Of Blood
8. Patient Safety Forces Closure Of Hospital
9. Farm Boy Airlifted by PSNI helicopter To Safety
10. Strict Safety Measures On Import of Poultry From China
11. Botox Treatment Now With A Lesser Dose And Increased Safety
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/27/2017)... ... February 27, 2017 , ... It’s no ... which often leads to a host of health issues, including urinary incontinence. However, ... Society discovered that good overall muscle strength in older women, particularly in ...
(Date:2/27/2017)... (PRWEB) , ... February 27, 2017 , ... ... for Shamanic Healing and Spiritual Awakening, is happy to announce her “Spring ... mind and body, these individual customized retreats offer the winter-weary soul an excellent ...
(Date:2/27/2017)... (PRWEB) , ... February 27, 2017 , ... Elisa Guajardo Carothers is not your typical ... to studying to become a nun. Now, she writes about God, when she isn’t swimming ... Know BC and AD, Here is BS! (Before Satan),” she offers a comedic look at ...
(Date:2/27/2017)... ... February 26, 2017 , ... Miro is the ultimate smart media center that ... songs, movies, TV shows and much more apps for user exploration. Its innovative acoustic ... view of 1280 x 720 provides crisp images with remarkable clarity and color. The ...
(Date:2/27/2017)... ... 2017 , ... Sunshine Coast Health Centre (SCHC), one of ... https://www.sunshinecoasthealthcentre.ca/ , is proud to announce the addition of a registered massage ... commitment to innovation in drug rehab and alcohol treatment strategies beyond a "punishment" ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... , Feb. 24, 2017 Physician General Dr. ... and Alcohol Programs Jennifer Smith commended South ... training for and using naloxone, a life-saving overdose reversal ... , a recovery specialist and overdose survivor who was ... providers. "A significant part of fighting the ...
(Date:2/24/2017)... , Feb. 23, 2017 The U.S. ... the PhenoTest BC Kit, performed on the Pheno ... organisms that cause bloodstream infections and provide information ... respond to (antibiotic sensitivity). The test also reduces ... this important information, which can guide antibiotic treatment ...
(Date:2/24/2017)... , Feb. 23, 2017  Directors from Pharma To Market Pty ... have joined forces, resulting in the founding of Pharma To Market ... Pharma To Market are pleased to announce their expansion into ... Singapore . The company are delighted to appoint ... of the Singapore based entity. Joelle brings ...
Breaking Medicine Technology: