Navigation Links
Safest painkiller Ibuprofen found to cause severe GI bleeding

Gastrointestinal bleeding is three times more likely to occur in patients who take high doses of ibuprofen on a regular basis despite the safety profile of non-steroidal anti-inflammatory drugs (NSAIDs). // Furthermore, the effect can be observed as early as three days after starting an ibuprofen regimen.

Ibuprofen is considered to have one of the most favorable safety profiles of all of the traditional non-selective NSAIDs, touted as the painkiller with the fewest side effects and lowest incidence of ulcers or GI bleeding.

Researchers have expressed concern over people with chronic pain such as arthritis who often increase the recommended dose of their painkillers. They should be made aware of the fact that it can have adverse effects with respect to the gastrointestinal tract.

Of all the NSAIDs available over-the-counter, ibuprofen is regarded to have the least harmful effects on the GI tract. However, the study shows that healthy, young people and older people are at great risk of internal bleeding and should speak with their doctor to determine the risks of taking large amounts of ibuprofen.

The study included 68 healthy volunteers who were given either four weeks of an ibuprofen regimen or a placebo. Prior to starting the regimen, patients were evaluated for a one-week control period to demonstrate that they were not bleeding.

It was found that those taking ibuprofen for 28 days experienced blood loss that was 3.64-fold greater than the placebo group. On average, those taking ibuprofen experienced blood loss as low as 40mL and as high as 299mL. Other side effects anemia and other adverse events can be observed at any dose of ibuprofen.

It is hoped that these findings will bring attention to the reality of the amount of painkillers potentially being used by patients at home.


'"/>




Page: 1

Related medicine news :

1. Breast Milk Safest For Child Till Six Months of Age
2. Drug dilemma confronts users of painkillers
3. Calcitriol [Vitamin D] with combination of painkillers for cancer treatment
4. Codeine-based painkillers to be used cautiously
5. Ibuprofen weakens aspirins effect
6. Ibuprofen to lower risk of Parkinson’s diseas
7. Use Of Ibuprofen Safe For Short Periods
8. Ibuprofen and Vitamins C and E Could Halt Alzheimers
9. Long-term Ibuprofen Therapy After Brain Injury Deteriorate Cognitive Abilities
10. Children Find Effective Pain Relief With Ibuprofen
11. Ibuprofen Risky for Heart Patients?
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... , ... Ellevate Network, the leading network for professional women, brought together some ... at their inaugural Summit in New York City in June. The event was livestreamed ... over 3 million. To watch the Mobilize Women video, click here . ...
(Date:10/13/2017)... ... 13, 2017 , ... Talented host, actor Rob Lowe, is ... a new episode of "Success Files," which is an award-winning educational program broadcasted ... each subject in-depth with passion and integrity. , Sciatica occurs when the sciatic ...
(Date:10/13/2017)... ... ... On The Brink”: the Christian history of the United States and the loss of ... William Nowers. Captain Nowers and his wife, Millie, have six children, ten grandchildren, ... Navy. Following his career as a naval aviator and carrier pilot, he spent ...
(Date:10/12/2017)... ... 12, 2017 , ... Planet Fitness, one of the largest and fastest growing ... open a flagship location in Covington, LA at 401 N. U.S. Highway 190, in ... to Office Depot in the Holiday Square shopping center. Its location allows it to ...
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris ... of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking ... in the field of medical informatics, this prestigious award is presented to an individual ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... announces the European launch of their new low volume, high throughput ... Cambridge, U.K on October 4th. The new ... unprecedented speed and sensitivity while using far less sample volume through ... ... ...
(Date:9/28/2017)... 2017 Cohen Veterans Bioscience and Early Signal ... wearable and home sensors for real-time monitoring of patients ... a nonprofit organization focused on disruptive health solutions for ... analytical system to record and integrate behavioral, cognitive, physiological ... ...
(Date:9/25/2017)... 25, 2017   Montrium , an industry ... today—from the IQPC Trial Master Files & Inspection ... that EastHORN Clinical Services has selected eTMF ... TMF management. EastHORN, a leading European contract research ... increase transparency to enable greater collaboration with sponsors, ...
Breaking Medicine Technology: