Navigation Links
Safest painkiller Ibuprofen found to cause severe GI bleeding

Gastrointestinal bleeding is three times more likely to occur in patients who take high doses of ibuprofen on a regular basis despite the safety profile of non-steroidal anti-inflammatory drugs (NSAIDs). // Furthermore, the effect can be observed as early as three days after starting an ibuprofen regimen.

Ibuprofen is considered to have one of the most favorable safety profiles of all of the traditional non-selective NSAIDs, touted as the painkiller with the fewest side effects and lowest incidence of ulcers or GI bleeding.

Researchers have expressed concern over people with chronic pain such as arthritis who often increase the recommended dose of their painkillers. They should be made aware of the fact that it can have adverse effects with respect to the gastrointestinal tract.

Of all the NSAIDs available over-the-counter, ibuprofen is regarded to have the least harmful effects on the GI tract. However, the study shows that healthy, young people and older people are at great risk of internal bleeding and should speak with their doctor to determine the risks of taking large amounts of ibuprofen.

The study included 68 healthy volunteers who were given either four weeks of an ibuprofen regimen or a placebo. Prior to starting the regimen, patients were evaluated for a one-week control period to demonstrate that they were not bleeding.

It was found that those taking ibuprofen for 28 days experienced blood loss that was 3.64-fold greater than the placebo group. On average, those taking ibuprofen experienced blood loss as low as 40mL and as high as 299mL. Other side effects anemia and other adverse events can be observed at any dose of ibuprofen.

It is hoped that these findings will bring attention to the reality of the amount of painkillers potentially being used by patients at home.


'"/>




Page: 1

Related medicine news :

1. Breast Milk Safest For Child Till Six Months of Age
2. Drug dilemma confronts users of painkillers
3. Calcitriol [Vitamin D] with combination of painkillers for cancer treatment
4. Codeine-based painkillers to be used cautiously
5. Ibuprofen weakens aspirins effect
6. Ibuprofen to lower risk of Parkinson’s diseas
7. Use Of Ibuprofen Safe For Short Periods
8. Ibuprofen and Vitamins C and E Could Halt Alzheimers
9. Long-term Ibuprofen Therapy After Brain Injury Deteriorate Cognitive Abilities
10. Children Find Effective Pain Relief With Ibuprofen
11. Ibuprofen Risky for Heart Patients?
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Safest painkiller Ibuprofen found cause severe bleeding

(Date:3/3/2015)... Angeles, CA (PRWEB) March 03, 2015 ... Boost , a fast weight loss product that is ... country. This is because it contains ingredients that help ... Boost is a new combination diet product thought to ... Metabolism Boost contains three ingredients, all directed at ...
(Date:3/3/2015)... Getting to the truth of the matter is ... at stake. So when it comes to physical therapy – ... – it’s vital to separate fact from fiction in order ... Sridhar Yalamanchili, PT, MSPT, and Director of Rehabilitation at ... nationwide survey by the American Physical Therapy Association (APTA) revealed ...
(Date:3/3/2015)... Spain (PRWEB) March 03, 2015 The authors ... best health care for the future is a good and ... by Xlibris UK) the authors have a created an ingenious ... & cooked vegetarian & vegan meals. , “Crude Food” ... food intolerances and allergies, mainly caused by over processed ...
(Date:3/3/2015)... HealthCarePoint (HCP) , the ... today that it has completed development of the ... Standards Consortium (CDISC). HCP will continue to provide ... training and certifications globally. HCP’s in-kind services will ... as well as development of dynamic identification for ...
(Date:3/3/2015)... 03, 2015 Motion Graphics ... of a new plugin FCPX3D Confetti designed exclusively for ... exploding transition using confetti particles inside FCPX,” said Christina ... FCPX3D Confetti transition, users will have fun as they ... from one clip to the next with 3D tumbling ...
Breaking Medicine News(10 mins):Health News:Diet Doc Discloses the Ingredients in their Powerful New Metabolism Boost for Controlled Appetite, Fast Weight Loss and Improved Mood 2Health News:Diet Doc Discloses the Ingredients in their Powerful New Metabolism Boost for Controlled Appetite, Fast Weight Loss and Improved Mood 3Health News:Diet Doc Discloses the Ingredients in their Powerful New Metabolism Boost for Controlled Appetite, Fast Weight Loss and Improved Mood 4Health News:Separating Fact from Fiction about Physical Therapy 2Health News:Separating Fact from Fiction about Physical Therapy 3Health News:New book ‘Crude Food’ gives readers ingenious ways to create healthy meals 2Health News:New book ‘Crude Food’ gives readers ingenious ways to create healthy meals 3Health News:HealthCarePoint Completes CDISC BlueCloud Transnational Commerce Through In-kind Donations 2Health News:HealthCarePoint Completes CDISC BlueCloud Transnational Commerce Through In-kind Donations 3Health News:A new Confetti Generator entitled FCPX3D Confetti was released today from Pixel Film Studios for Final Cut Pro X 2
... News) -- Premature infants have fewer types of bacteria in ... However, the bacteria and other microbes often found ... researchers from Duke University Medical Center noted. "You see ... they seem to be stuck -- they have fewer types ...
... function were common and long-lasting during the first ... to a new study from Johns Hopkins University ... risk factor for impaired physical function. "Early ... evaluated as a potential,intervention to improve long-term outcomes ...
... , THURSDAY, Dec. 8 (HealthDay News) -- Increased consumption ... of breast cancer recurrence, new research finds. Researcher ... University of California, San Diego, looked at changes in ... potatoes, that breast cancer survivors ate over a one-year ...
... quantifying the amount of three different HER growth proteins, ... breast cancer , did not predict a patient,s outcome ... Herceptin, say Mayo Clinic researchers. HER2-positive breast cancer gets ... factor receptor 2 that promotes cancer cell growth. ...
... By Serena Gordon HealthDay Reporter , THURSDAY, Dec. ... the risk of stroke dropped about 22 percent in people ... These people didn,t yet have high blood pressure, but they ... significant reduction in the rate of heart attacks for people ...
... used to spot where people live, satellite images of ... festering among them, too, according to new research. ... Dec. 9 that nighttime-lights imagery presents a new ... revealing the population boom that typically coincides with seasonal ...
Cached Medicine News:Health News:Preemies Infected With More Dangerous Types of Bacteria: Study 2Health News:Depressive symptoms and impaired physical function are frequent and long-lasting after ALI 2Health News:Starchy Foods May Boost Risk of Breast Cancer Recurrence 2Health News:Starchy Foods May Boost Risk of Breast Cancer Recurrence 3Health News:Proteins do not predict outcome of herceptin treatment in HER2-positive breast cancer 2Health News:Treating Prehypertension Lowers Stroke Risk: Study 2Health News:Treating Prehypertension Lowers Stroke Risk: Study 3Health News:Princeton study: Nighttime images help track disease from the sky 2Health News:Princeton study: Nighttime images help track disease from the sky 3Health News:Princeton study: Nighttime images help track disease from the sky 4Health News:Princeton study: Nighttime images help track disease from the sky 5Health News:Princeton study: Nighttime images help track disease from the sky 6
(Date:3/3/2015)... -- Although lung cancer is the third most prevalent ... drugs in the market for its treatment. Further, popular ... patent expiry in 2015 and 2017 respectively. As such, ... drug manufacturers are vying to tap into. Approximately 130 ... (SCLC) and non-small cell lung cancer (NSCLC) are in ...
(Date:3/3/2015)... ROCKVILLE, Md. , March 3, 2015  CASI ... company dedicated to the acquisition, development and commercialization of ... for the global market with a commercial focus on ... K. Ren , Ph.D., CASI,s Chief Executive Officer, will ... ROTH Conference, to be held March 8-11 in Dana ...
(Date:3/3/2015)... 2015  Soligenix, Inc. (OTCQB: SNGX) (Soligenix or ... that address unmet medical needs in the areas ... has received a positive recommendation from the Data ... company,s Phase 2 study evaluating SGX942, a first-in-class ... oral mucositis in patients undergoing chemoradiation (CRT) therapy ...
Breaking Medicine Technology:Targeted Lung Cancer Therapies Are Supplanting Conventional Treatments 2Targeted Lung Cancer Therapies Are Supplanting Conventional Treatments 3CASI Pharmaceuticals To Present At The 27th Annual ROTH Conference 2Soligenix Announces Positive Recommendation by Data Review Committee on its Phase 2 Clinical Trial of SGX942 for the Treatment of Oral Mucositis in Head and Neck Cancer Patients 2Soligenix Announces Positive Recommendation by Data Review Committee on its Phase 2 Clinical Trial of SGX942 for the Treatment of Oral Mucositis in Head and Neck Cancer Patients 3Soligenix Announces Positive Recommendation by Data Review Committee on its Phase 2 Clinical Trial of SGX942 for the Treatment of Oral Mucositis in Head and Neck Cancer Patients 4Soligenix Announces Positive Recommendation by Data Review Committee on its Phase 2 Clinical Trial of SGX942 for the Treatment of Oral Mucositis in Head and Neck Cancer Patients 5Soligenix Announces Positive Recommendation by Data Review Committee on its Phase 2 Clinical Trial of SGX942 for the Treatment of Oral Mucositis in Head and Neck Cancer Patients 6
... IRVINE, Calif.--(BUSINESS WIRE)--Apr 30, 2007 - Cobalis ... specializing in,anti-allergy medications, today announced it has ... that it would need,more time to combine ... single,database before un-blinding and conducting the statistical ...
... WIRE)--Apr 30, 2007 - Hemispherx Biopharma,Inc. (AMEX: ... of Immunology, April 2007) that explains the ... (Poly I : Poly C(12)U), a double-stranded ... Fatigue Syndrome and as an,adjuvant to other ...
Cached Medicine Technology:Cobalis Expects to Report Phase III Top-Line Results in May 2New Report Illuminates Ampligen's Unique Mechanism of Action 2New Report Illuminates Ampligen's Unique Mechanism of Action 3New Report Illuminates Ampligen's Unique Mechanism of Action 4
For the quantitative in vitro determination of Alkaline Phosphatase in serum or plasma....
... EMR,systems require you to,change the ... only,electronic patient charting,solution designed to ... around,five specific criteria to,enhance overall ... you to see,more patients in ...
... StatStrip point-of-care glucose monitor elevates bedside glucose ... performance that approaches the quality of central ... well glucose measuring strip technology. Current ... Novas exclusive Multi-Well system measures and corrects ...
... EMS provides service to companies in many ... stores and restaurants.There are no hidden charges at ... equipment and service are among the lowest in ... array of services ranging from MasterCard/Visa processing to ...
Medicine Products: