Navigation Links
Safest painkiller Ibuprofen found to cause severe GI bleeding

Gastrointestinal bleeding is three times more likely to occur in patients who take high doses of ibuprofen on a regular basis despite the safety profile of non-steroidal anti-inflammatory drugs (NSAIDs). // Furthermore, the effect can be observed as early as three days after starting an ibuprofen regimen.

Ibuprofen is considered to have one of the most favorable safety profiles of all of the traditional non-selective NSAIDs, touted as the painkiller with the fewest side effects and lowest incidence of ulcers or GI bleeding.

Researchers have expressed concern over people with chronic pain such as arthritis who often increase the recommended dose of their painkillers. They should be made aware of the fact that it can have adverse effects with respect to the gastrointestinal tract.

Of all the NSAIDs available over-the-counter, ibuprofen is regarded to have the least harmful effects on the GI tract. However, the study shows that healthy, young people and older people are at great risk of internal bleeding and should speak with their doctor to determine the risks of taking large amounts of ibuprofen.

The study included 68 healthy volunteers who were given either four weeks of an ibuprofen regimen or a placebo. Prior to starting the regimen, patients were evaluated for a one-week control period to demonstrate that they were not bleeding.

It was found that those taking ibuprofen for 28 days experienced blood loss that was 3.64-fold greater than the placebo group. On average, those taking ibuprofen experienced blood loss as low as 40mL and as high as 299mL. Other side effects anemia and other adverse events can be observed at any dose of ibuprofen.

It is hoped that these findings will bring attention to the reality of the amount of painkillers potentially being used by patients at home.


'"/>




Page: 1

Related medicine news :

1. Breast Milk Safest For Child Till Six Months of Age
2. Drug dilemma confronts users of painkillers
3. Calcitriol [Vitamin D] with combination of painkillers for cancer treatment
4. Codeine-based painkillers to be used cautiously
5. Ibuprofen weakens aspirins effect
6. Ibuprofen to lower risk of Parkinson’s diseas
7. Use Of Ibuprofen Safe For Short Periods
8. Ibuprofen and Vitamins C and E Could Halt Alzheimers
9. Long-term Ibuprofen Therapy After Brain Injury Deteriorate Cognitive Abilities
10. Children Find Effective Pain Relief With Ibuprofen
11. Ibuprofen Risky for Heart Patients?
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/28/2017)... ... 2017 , ... Viewers likely know Rob Lowe from such 80s hits as ... his work on NBC’s The West Wing and Parks and Recreation. But recently, Lowe’s ... which puts the spotlight on important modern-day issues that face today’s society. One of ...
(Date:5/27/2017)... ... 2017 , ... From May 21-23, hearing healthcare professionals gained a competitive edge ... the Marriott Syracuse Downtown Hotel in Syracuse, New York. , As EarQ’s technology ... healthcare providers to help them stay ahead in the industry. At the event, EarQ ...
(Date:5/26/2017)... ... May 26, 2017 , ... Leading CEOs from biotech, pharmaceutical, ... and 31st at The Four Seasons Hotel Boston. , The Boston CEO ... offering exclusive access to key decision makers who influence deal making and investment. ...
(Date:5/26/2017)... ... ... A new analysis of community health data reveals that four out of the ... the average cost of healthcare rising and the U.S. senior population expected to double ... of where they live. An annual 2017 report looked at a variety of community ...
(Date:5/26/2017)... ... 2017 , ... After raising nearly $30,000 on Kickstarter , about three-times ... at a discounted crowdfunding price on Indiegogo . , “Along with creating an ... to bring a fidget toy to the market that was made of superior quality ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... Inc. (Nasdaq: HOLX ) announced today the ... April 1, 2017 .   GAAP diluted earnings per ... prior year period as the sale of the blood ... diluted EPS of $0.50 increased 6.4%.  Revenue of $715.4 ... Excluding the effects of blood screening and the acquired ...
(Date:5/10/2017)... , May 10, 2017 Radiology has become ... its costs have also spiraled to the number one ... to radiology than ever before as the most complete ... a patient with lower back pain an MRI may ... reason for pain, resulting in entirely different treatment protocols.  ...
(Date:5/9/2017)... May 9, 2017  Demonstrating its commitment to ... directors for the Pharmaceutical Research and Manufacturers of ... Biopharmaceutical companies will now have to meet new ... be eligible to join PhRMA. "By ... is sending a clear message that being a ...
Breaking Medicine Technology: