Navigation Links
Safer Method for Large-Scale Malaria Screening Developed

Researchers at the Johns Hopkins Bloomberg School of Public Health’s Malaria Research Institute have developed a new test for detecting //the malaria parasite in human urine and saliva. Although not a diagnostic test for determining treatment, the method could potentially reduce the need for blood sampling in epidemiological studies where large-scale malaria screening is required. Drawing blood increases the risk of spreading HIV and other diseases, particularly in those developing countries where both HIV and malaria are prevalent. Blood drawing must also be performed by trained personnel, whereas urine and salvia sampling does not.

“Testing urine or saliva could be an easier and safer way to collect the information needed for studying malaria in communities. For instance, it could be used in studies to determine if a population is growing resistant to malaria drugs, which is a very serious problem,” said David J. Sullivan, MD, senior author of the study and a professor in the Bloomberg School’s Malaria Research Institute.

The test uses polymerase chain reaction (PCR), a technique for duplicating and then examining unique bits of DNA from a sample, thereby allowing DNA to be multiplied in the laboratory. The same PCR technique is used for examining malaria in blood, but has never been applied to urine and saliva samples.

The study was conducted in collaboration with colleagues at the Malaria Research Institute’s research hospital in Macha, Zambia. Urine and salvia samples were obtained from 47 volunteers with malaria and 4 without, and were then examined with the PCR method. DNA from the Plasmodium falciparum, the parasite that causes malaria, was replicated at higher levels from the saliva compared to the urine samples. However, neither method was as sensitive as that using blood samples.

“Programs for monitoring antimalarial drug and vaccine efficacy could therefore adopt such a bloodless method, while maintaining h igh sensitivity for clinically significant infections,” said Sungano Mharakurwa, PhD, lead author of the study and a researcher with the Malaria Research Institute in Macha.


Related medicine news :

1. Heart Surgery Is Getting Safer for the Old
2. Estrogen Patch is Safer than Pills for Heart
3. Traffic Violations Result in Safer Drivers
4. British company developing ‘Safer Cigarettes
5. Surgery Simulators Offer Better Surgeons And Safer Surgeries
6. Mapping Of Brain Highly Beneficial For Safer Brain Tumor Surgery
7. Doppler USG-Safer Technique For Detection Of Rh Diseases In Fetus
8. Enbrelr Enters Safer Zone After Recent Research
9. Child-Proof: Brain Mapping Safer for Children than Previously Thought
10. Laser Surgery Safer Than Contact Lenses?
11. Consumers, Caregivers Taking Steps to Safer Surgery
Post Your Comments:

(Date:6/27/2016)... ... June 27, 2016 , ... TherapySites, ... its affiliation with Tennessee Counseling Association. This new relationship allows TherapySites ... Tennessee Counseling Association, adding exclusive benefits and promotional offers. , "TCA is extremely ...
(Date:6/26/2016)... , ... June 27, 2016 , ... Quality metrics are ... in many ways they remain in the eye of the beholder, according to experts ... publication of The American Journal of Managed Care. For the full issue, click ...
(Date:6/26/2016)... ... , ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop a ... fitness app plans to fix the two major problems leading the fitness industry today:, ... type program , They don’t eliminate all the reasons people quit their exercise ...
(Date:6/25/2016)... ... ... closing of Bruton Memorial Library on June 21 due to a possible lice infestation, as ... of head lice: the parasite’s ability to live away from a human host, and to ... one in the event that lice have simply gotten out of control. , As lice ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
(Date:6/23/2016)... and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma ... as the company,s second affiliate in Latin America . ... ... Astellas Farma Colombia ... ...
(Date:6/23/2016)... 23, 2016  Guerbet announced today that it has ... Horizon Award . One of 12 suppliers ... for its support of Premier members through exceptional local ... and commitment to lower costs. ... of our outstanding customer service from Premier," says ...
Breaking Medicine Technology: