Navigation Links
Sacroplasty Safe and Effective to Reduce Low Back Pain

The injection is safe when performed by physicians experienced with the technique//, and pain reduction is both swift and sustained, according to the one-year, multi-center cohort study.

Among the 25 patients enrolled in the uncontrolled study, the mean pain score on a 10-point visual analog scale was 7.3 at baseline, 2.7 immediately post-procedure, 1.4 at two weeks, 0.5 at 24 weeks, and 0.3 at 52 weeks, according to Michael Frey, MD, a NASS member and physiatrist at Advanced Pain Management and Spine Specialists in Fort Myers, FL.

There are currently no treatments for sacral insufficiency fractures. Recovery is typically slow, and pain may linger for up to a year. In some cases, symptoms and disability last longer.

To calm the pain, physicians often prescribe bed rest, painkillers, corsets, or other measures. However, these can put patients at increased risk of thromboembolism, skin breakdown, pressure ulcers, constipation, depression, progressive osteoporosis, and reduced muscle strength and cardiac function.

“These patients are miserable,” said Frey, who has performed sacroplasty on nearly 50 patients.

To explore better alternatives, Frey and others have adapted techniques developed for vertebroplasty in the lumbar spine. In vertebroplasty, physicians use fluoroscopic guidance to inject polymethylmethacrylate (PMMA) into osteoporotic compression fractures. After injection the acrylic bone cement hardens. The technique was designed to stabilize the fracture, reduce pain, and improve function.

Frey and colleagues reported on consecutive patients with osteoporosis who had incapacitating low back or gluteal pain and a sacral insufficiency fracture documented on MR imaging or CT scan, and who failed or could not tolerate conservative care. The authors excluded patients with fractures caused by malignancies.

About one in seven patients experienced complete relief of pain within 30 minute s, said Frey. Approximately one-fourth were pain-free at two weeks and about one-third at four weeks. Frey said there were no complications associated with the procedure at any time, though one patient died of what was deemed unrelated pulmonary disease within four weeks of undergoing the procedure. Excluding this patient, all but two patients reported 75% to 100% satisfaction at one year.

“Sacroplasty is a dramatic leap forward,” said Frey.

Most previous reports about sacroplasty have been small case series with short followup. They suggested that the procedure is technically feasible and leads to short-term pain relief. But there is scant prospective evidence on the safety and efficacy of sacroplasty in larger cohorts followed for longer periods of time.

Frey says the procedure can be technically demanding, and recommends physicians have extensive experience in vertebral augmentation. Potentially, cement can leak outside the sacrum and compromise the sacral nerve root, the sacral spinal canal, or sacroiliac joint.

Several years ago, the FDA issued a surprisingly sharp warning about the risks associated with vertebroplasty, including pulmonary embolism, respiratory and cardiac failure, and death. (FDA Public Health Web Notification: Complications related to the use of bone cement in vertebroplasty and kyphoplasty procedures, October 31, 2002; http://www.fda.gov/cdrh/safety/bonecement.html.)

Frey noted that sacroplasty is an off-label use of PMAA, and there is no Medicare code for the procedure, so reimbursement is problematic. His cost for one kit is about $400. He said he performs the service at no charge and receives no industry funding for his research.

Frey would like to see controlled trials to compare sacroplasty to a sham procedure. It is conceivable, he said, that sacroplasty is no better than placebo. In his study, none of the patients who declined sacroplasty was pain free at 12 weeks , though at six months and one year their pain had subsided to a level comparable to that of patients who received sacroplasty.

Source-Newswise
RM
'"/>




Related medicine news :

1. New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
2. Inhaled Steroids Safe & Effective for Children with Asthma
3. ZD1839 Proves Effective - A Breakthrough in fighting Lung Cancer
4. Fluoride Found Effective in Osteoporosis
5. Aspirin and Warfarin Are Equally Effective for Stroke Prevention
6. Implantable Contact Lens Found Safe and Effective
7. Effective And Economical Agent For Anthrax
8. Stem Cell Transplants May Be Effective For MS Patients
9. Effective therapy for Huntingtons disease
10. Chemotherapy Effective for Bladder Cancer
11. Drug Effective for Vascular Dementia
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/2/2016)... ... , ... In honor of National Physical Fitness and Sports Month in May, ... fitness journey on social media. , The foot care company, which specializes in ... voucher each week during May to one winner. , “Whether the goal is to ...
(Date:5/2/2016)... ... May 02, 2016 , ... Dr. Philip Shindler, dentist in ... day treatments. In the past, many necessary dental treatments could require multiple appointments to ... anesthetic shots and extra chair time. Not only could this be inconvenient, but it ...
(Date:5/2/2016)... ... , ... MedPro Waste Disposal, LLC (MedPro) is proud to announce that it ... back service for an all-inclusive rate. MedPro Disposal President, Dan Hansen, says, “We’re really ... of the clients in the country who are looking for an alternative to their ...
(Date:5/2/2016)... ... May 02, 2016 , ... Zitter ... Specialty Pharmacy Patient Satisfaction Award that will recognize specialty pharmacies for their achievements ... Zitter Health Insights’ Specialty Pharmacy Patient Satisfaction Survey compiled throughout 2016. Results will ...
(Date:5/2/2016)... ... May 02, 2016 , ... The 2016 World Ultimate & Guts Championship (WUGC) Mixed ... Manhattan College, made the cut. The WUGC is being held in London, England this year ... gold in the men’s division, another gold in the women’s masters division, and a silver ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... April 27, 2016 Transparency Market ... Devices Market - Global Industry Analysis, Size, Share, Growth, ... report, the global skincare devices market was valued at ... expand at a CAGR of 10.1% from 2015 to ... Browse the full Skincare Devices Market (Treatment Device - ...
(Date:4/27/2016)... April 27, 2016 Tie-up with ... initiative to save newborns   Fortis ... & newborns in collaboration with Breast Milk Foundation (BMF), a ... Pasteurized Human Milk Bank, ,Amaara, in Delhi-NCR today. This non-profit ... source for infants and should be available to babies deprived ...
(Date:4/27/2016)... , April 27, 2016 Shire plc ... Jeff Poulton , Chief Financial Officer, will present at the ... Boston, MA on Wednesday, May 04, 2016, 10:00 ... will be available on the Presentations and Webcasts section of ... of the webcast will be available on this same website ...
Breaking Medicine Technology: