Navigation Links
Rodents to be replaced with Dogs for cancer Research

Researchers from National Cancer Institute, US is to start testing their drug efficacy trial on dogs as the researchers feel that drug metabolize, enzyme kinetics and drug action mechanisms in dogs are similar to humans than that of rodents//.

Dr. Chand Khanna, Veterinary Oncologist said, “It turns out that many cancers, such as lymphoma, melanoma and osteosarcoma, are well represented in dogs and the dogs will help us prioritize the agents that go into human clinical trials and help make those trials more efficient”.

The enzyme systems and kinetics pathway in humans are similar in dogs which make the researchers measure the enzyme effect on substrates and measure the endpoint of the reactions in an easier way as metabolize rate of drugs in humans and dogs are similar. But researchers have to test the drug toxicity of their new cancer drugs in rodents before testing the drug on dogs.

Source: Nature Medicine.
'"/>




Page: 1

Related medicine news :

1. Longer-Lived Rodents Have Lower Levels of Thyroid Hormone
2. Glucose Causes Death of Brain Cells in Rodents Following Hypoglycemic Coma
3. Heart valve surgery may be replaced by new heart therapy
4. Vitamin B12 can help in detecting cancers
5. Want skin cancer? Please have a cigarette
6. New hope for cancer victims – will vaccine cure the deadly bug
7. Clintons new problem - Is the outgoing American president suffering from skin cancer?
8. Are cancer patients being taken for a ride?
9. Breast cancer treatment to be determined by gene test
10. Ductal lavage may detect early breast cancer
11. Beware of the oral patch! It could be cancer!!!
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/24/2017)... ... July 24, 2017 , ... Sharon Kleyne, host of the nationally ... on VoiceAmerica sponsored by Nature’s Tears® EyeMist® recently talked on the air about an ... China. , The article by Zidor Aldama described the situation in which Chinese children ...
(Date:7/24/2017)... CUMBERLAND, PA (PRWEB) , ... July 24, 2017 ... ... by 2030, today CURE announced that they have enrolled over 100,000 children in ... 158,000 afflicted children born every year in areas where treatment is limited or ...
(Date:7/24/2017)... ... July 24, 2017 , ... Advanced Dermatology, P.C. ... York, (516) 784-5858. The office opened earlier this summer and is currently accepting ... Fruma Leah Wiederman. , Advanced Dermatology, P.C. founder and medical director Dr. ...
(Date:7/24/2017)... ... ... The Center for Addiction Recovery Training (CART), the training ... Multiple Pathways of Recovery Conference on October 23-26, 2017. This year, the conference ... principle – a belief in multiple pathways of recovery, aims to bring many ...
(Date:7/23/2017)... CANADA (PRWEB) , ... July 23, 2017 , ... ... of single sport specialization is critical, say researchers presenting their work today at ... Toronto, Canada. , “Our study is the first one to prospectively document ...
Breaking Medicine News(10 mins):
(Date:7/13/2017)... July 13, 2017  New York City-based market research firm ... should be aware of.  From new products to new costs, ... in a recently completed study, Potential Pipeline Disruptors . ... 1.  Age-Driven Growth - True Impact ... aware of the impact the growing population and, to a ...
(Date:7/11/2017)... , July 11, 2017  The global market ... revenues of approximately $394.1 million in 2016.  Although in ... of solid growth, in particular as a result of ... practice, and the recent introduction of a significant number ... for less-invasive testing of tumor biomarkers to guide treatment ...
(Date:7/10/2017)... , July 10, 2017 The Institute ... test methods, is the recipient of a VITROCELL® inhalation ... PETA International Science Consortium. The device, which is designed ... to expose human lung cells to airborne test materials ... will use the VITROCELL® system for testing combustible tobacco ...
Breaking Medicine Technology: