Navigation Links
Rituximad Can Treat Chronic Graft-Versus-Host Disease: Study

s thinking has been challenged by research, by Dana-Farber's Jerome Ritz, MD, and others, that indicates that immune system B cells, as well as T cells, play a critical role in GVHD. (T cells are so named because they mature in the thymus gland, while B cells are derived from bone marrow.) This hypothesis gained traction when laboratory studies and small clinical trials showed that rituximab, which specifically targets B cells, could be effective against GVHD.

The new study reinforces those findings with the largest group of chronic GVHD patients yet treated with rituximab. The patients in the study had chronic GVHD that was resistant to the standard therapy of corticosteroids, and were on stable doses of other immune system-suppressing medications. Twenty of the study's 21 participants completed at least one 4-week course of treatment. All had received stem cell transplants at least six months before enrolling in the study.

In addition to reducing the severity of GVHD in nearly three-fourths of the study participants, rituximab enabled 68 percent of the participants to reduce the amount of corticosteroids they were taking by more than 50 percent. Patients reported few side effects of the rituximab therapy.

"We've demonstrated that anti-B cell therapy with rituximab is safe and effective for patients with steroid-resistant chronic GVHD," Cutler says. "It's becoming clearer that treatments for chronic GVHD will need to take account of both T cell and B cell activity in transplant recipients. The success of this approach suggests that anti-B cell therapies cold be tested as part of a strategy for preventing GVHD and treating it in its earliest stages.”

Dana-Farber Cancer Institute (http://www.danafarber.org) is a principal teaching affiliate of the Harvard Medical School and is among the leading cancer research and care centers in the United States. It is a founding member of the Dana-Farber/Harvard Cancer Center (DF/HCC
'"/>




Page: 1 2 3

Related medicine news :

1. Advances in Treatment of Cataracts
2. Recommendations for Treatment of Blood Pressue
3. New FDA Approved Drug To Treat Migraine
4. Treatment for Menieres disease
5. Treatment for pre-menstrual syndrome is ineffective
6. Angiotensin-II-receptor blockers - Treat kidney failure
7. Cipro Has Cheaper Cousins to Treat Anthrax
8. Better Treatment for obesity
9. Gene Treatment for Heart Disease
10. Cyclosporin A Treats Leukemia Complications
11. New Way To Treat Lupus
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Rituximad Can Treat Chronic Graft Versus Host Disease Study

(Date:8/30/2015)... (PRWEB) , ... August 30, 2015 , ... Lizzie’s ... a back to school special. The company is currently offering lice head checks for ... addition, the company is offering a 10% discount on their lice treatment products. “With ...
(Date:8/30/2015)... ... August 30, 2015 , ... Nutritional Products International ... the expansion of global cosmeceutical and skin care brands. Mr. Fernandez comes ... last 25 years working in operations, purchasing and management for some of the ...
(Date:8/29/2015)... ... August 30, 2015 , ... Electronic Informed Consent ... – 3:00 p.m. EDT, http://www.fdanews.com/electronicinformedconsent , The simple fact about electronic ... , Clinical trial sites can now use audio, video and interactivity ...
(Date:8/29/2015)... CA (PRWEB) , ... August 29, 2015 , ... Dr. ... a mission. His mission is to increase acceptance of the chiropractic field in ... medications that further debilitate them. Although Chiropractic was made available to the VA ...
(Date:8/29/2015)... ... August 29, 2015 , ... Hamstring strain ... stretching, soft tissue manipulation. Platelet rich plasma injections also have mixed results. ... improve treatment outcomes. This localized treatment seems to address the symptoms and ...
Breaking Medicine News(10 mins):Health News:Lizzie’s Lice Pickers Announces Back to School Head Check Special and Discounted Lice Treatment Products 2Health News:NPI Executive Vice President Leads Cosmeceutical Expansion 2Health News:FDAnews Announces — Electronic Informed Consent for Clinical Trials: Best Practices Webinar, Sept. 15, 2015 2Health News:FDAnews Announces — Electronic Informed Consent for Clinical Trials: Best Practices Webinar, Sept. 15, 2015 3Health News:FDAnews Announces — Electronic Informed Consent for Clinical Trials: Best Practices Webinar, Sept. 15, 2015 4Health News:The Patriot Project brings Chiropractic Care to the Armed Forces and their Families - Rapid Release Technology Joins the Effort to Recruit more Doctors to Pledge 2Health News:NEW APPROACH for Treatment of Recurrent Hamstring Strains and Hamstring Tendinosis is Available for the First Time in NYC 2Health News:NEW APPROACH for Treatment of Recurrent Hamstring Strains and Hamstring Tendinosis is Available for the First Time in NYC 3
... November 16 to benefit Girls on the Run-Chicago, CHICAGO, ... relax, shop, travel and more with all the auction items ... Friday November 16 at the,Chicago Cultural Center. The annual event, ... music from the Underwater,People, cocktails, hors d,oeuvres and plenty of ...
... 9 As part of the Company,s,commitment to ... its support today for the amendment to the ... sold in schools proposed by Senate,Agriculture Committee Chairman ... "Mars US applauds Senators Harkin and Murkowski for ...
... Nov. 9 Give an Hour, a,non-partisan, non-profit organization ... loved ones, announces there are 750,providers nationwide on its ... its network 10 percent, or 40,000,people, of the approximately ... an average fee of $100 an hour, this would ...
... Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ), ... a national survey where 60 percent of 121 mothers ... Deficit Hyperactivity Disorder (ADHD) medication stopped working before 6 ... 500 parents of children with ADHD regarding the duration ...
... shed light on why some people suffer from recurrent ... cause characterized by a drop in blood pressure, fainting ... some of these individuals, researchers have found mast cells ... that have a mutated cell surface receptor that disturbs ...
... Globe, Sculpture Promotes Environmental Protection Awareness, NORTH CHICAGO, ... Lake County, Abbott (NYSE: ABT ) has donated ... exhibit in Chicago to the Lake,County Forest Preserves (LCFP) ... in North Chicago, Ill. The "Cool Globes" program, ...
Cached Medicine News:Health News:Chicago's Premier Sports and Fitness Auction is Back! 2Health News:Mars US Supports Harkin/Murkowski Amendment to Update Nutrition Standards for Foods Sold in Schools 2Health News:Non-Profit Calls on Mental Health Professionals to Honor Veterans Day by 'Giving an Hour' of Free Counseling to Returning Veterans 2Health News:Parents survey: Perceptions of the duration of their child's ADHD medication 2Health News:Abnormal immune cells may cause unprovoked anaphylaxis 2Health News:Abnormal immune cells may cause unprovoked anaphylaxis 3Health News:Abbott Donates 'Cool Globe' to Lake County Forest Preserves for Permanent Display at Greenbelt Cultural Center 2Health News:Abbott Donates 'Cool Globe' to Lake County Forest Preserves for Permanent Display at Greenbelt Cultural Center 3
(Date:8/28/2015)... Aug. 28, 2015 ... the addition of the "Investigation Report on ... offering. Developed by Pharmacia & Upjohn ... agonist which effectively reduces intraocular pressure. As the ... (under the trade name of Xalatan) entered ...
(Date:8/28/2015)... DUBLIN , Aug. 28, 2015  Perrigo Company ... that it has completed the acquisition of leading OTC ... at €200 million. The transaction is a clear demonstration ... the Company,s leading European distribution network spanning 36 countries.  ... Joseph C. Papa commented, "We are excited to ...
(Date:8/28/2015)... 28 de agosto de 2015   Royal ... participación en el  Congreso de la ESC de ... recientes y novedosas, entre ellas HeartModel A.I.  , ... personas y la tecnología con los protocolos de ... los tratamientos y permitir atención en el hogar. ...
Breaking Medicine Technology:China Latanoprost Market Investigation Report 2015-2019 2Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 2Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 3Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 2Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 3Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 5
... CITY, Calif, Oct. 27 Cardica, Inc. (Nasdaq: ... System and its PAS-Port® Proximal Anastomosis System will be ... the Advances in Robotic and Hybrid Coronary Revascularization conference, ... Robotic Surgery and Saint Joseph,s Hospital in Atlanta, Georgia. ...
... YORK, Oct. 27 Delcath Systems, Inc. (Nasdaq: ... host a conference call to discuss its third quarter ... 2010 at 4:30 p.m. ET.  Eamonn Hobbs, President and ... will host the call. The dial-in number for the ...
Cached Medicine Technology:Cardica's Automated Anastomosis Systems Featured at Advances In Robotic And Hybrid Coronary Revascularization Meeting 2Cardica's Automated Anastomosis Systems Featured at Advances In Robotic And Hybrid Coronary Revascularization Meeting 3Delcath Systems Announces Third Quarter Progress Report Conference Call 2Delcath Systems Announces Third Quarter Progress Report Conference Call 3
The Greenberg retractor and handrest is a versatile, three level system offering efficient space planning, whereby each level has an assigned surgical task....
Io is a surgical digital microscope with head mounted display HMD (Callisto)....
A budget-priced microscope designed for ENT and neuro surgery....
... OME-8000 represents the finest integration ... expertise in optics, digital imaging, ... a surgical microscope. The surgical ... gives the surgeon an unprecedented ...
Medicine Products: