Navigation Links
Risk of colon cancer to be assessed by simple blood test

Colon cancer is the second most common forms of cancer, and is associated with a significant mortality. There is no single cause for colon cancer. The presence of benign growths in the colon, family history// of colon cancer, and dietary factors are some of the factors that predispose to colon cancer. The disease is completely treatable if diagnosed early.

Researchers are now trying to develop a practical test to predict a person's risk of colon cancer by looking for a particular biological marker in the blood. If successful, the test could be broadly applied to identify those who most need to be monitored with invasive but standard colonoscopy or who should make changes in their diet or in other factors to help lower their risk of developing colon cancer.

It has been suspected that genomic changes underlie cancer risk. The BRCA1 and BRCA2 genes implicated in breast and ovarian cancers are great examples, but they are applicable only to a small percentage -- less than one percent -- of women. The knowledge hasn't been translated yet into a broadly applicable way to identify individuals most at risk.

The changes associated with IGF-2 levels are linked to epigenetic mechanisms- changes in what is attached to genetic material. An epigenetic process called “imprinting normally controls the IGF-2 gene" in which the level of protein production proteins on which parent the copy came from.

For IGF-2, only the gene copy inherited from the father should be turned on, and that from the mother should be off. In about five percent to 10 percent of people, however, both copies of the gene are turned on -- a problem called loss of imprinting, leading to cancer formation.

The attempt is based on the fact that five percent to 10 percent of people have improper control of a growth-promoting gene called insulin-like growth factor 2 or IGF-2. It has been regarded that increased levels pf this protein is associated with the initia tion and subsequent development of colon cancer.

If the levels of IGF 2 are found to be linked to colon cancer and a blood test is developed to assess the levels to this protein, perhaps it could lead to a less invasive option for identification of high-risk individuals. It would be as simple as measurement of cholesterol levels as a risk factor for heart disease.
'"/>




Related medicine news :

1. Radiotherapy helps in colon cancer
2. Benefit of colonoscopy
3. Hydroxyurea derivatives kill colon cancer cells
4. Wheat wards off colon cancer
5. Defeating colon cancer
6. Calcium reduces colon cancer risk
7. Smoking risk precedes colon cancer
8. Implication of virus in colon cancer
9. New virtual colonoscopy procedure for easier colon screening
10. Long-term use of calcium supplements to prevent colon cancer
11. Aspirin may reduce he risk of colon cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: