Navigation Links
Risk of colon cancer to be assessed by simple blood test

Colon cancer is the second most common forms of cancer, and is associated with a significant mortality. There is no single cause for colon cancer. The presence of benign growths in the colon, family history// of colon cancer, and dietary factors are some of the factors that predispose to colon cancer. The disease is completely treatable if diagnosed early.

Researchers are now trying to develop a practical test to predict a person's risk of colon cancer by looking for a particular biological marker in the blood. If successful, the test could be broadly applied to identify those who most need to be monitored with invasive but standard colonoscopy or who should make changes in their diet or in other factors to help lower their risk of developing colon cancer.

It has been suspected that genomic changes underlie cancer risk. The BRCA1 and BRCA2 genes implicated in breast and ovarian cancers are great examples, but they are applicable only to a small percentage -- less than one percent -- of women. The knowledge hasn't been translated yet into a broadly applicable way to identify individuals most at risk.

The changes associated with IGF-2 levels are linked to epigenetic mechanisms- changes in what is attached to genetic material. An epigenetic process called “imprinting normally controls the IGF-2 gene" in which the level of protein production proteins on which parent the copy came from.

For IGF-2, only the gene copy inherited from the father should be turned on, and that from the mother should be off. In about five percent to 10 percent of people, however, both copies of the gene are turned on -- a problem called loss of imprinting, leading to cancer formation.

The attempt is based on the fact that five percent to 10 percent of people have improper control of a growth-promoting gene called insulin-like growth factor 2 or IGF-2. It has been regarded that increased levels pf this protein is associated with the initia tion and subsequent development of colon cancer.

If the levels of IGF 2 are found to be linked to colon cancer and a blood test is developed to assess the levels to this protein, perhaps it could lead to a less invasive option for identification of high-risk individuals. It would be as simple as measurement of cholesterol levels as a risk factor for heart disease.
'"/>




Related medicine news :

1. Radiotherapy helps in colon cancer
2. Benefit of colonoscopy
3. Hydroxyurea derivatives kill colon cancer cells
4. Wheat wards off colon cancer
5. Defeating colon cancer
6. Calcium reduces colon cancer risk
7. Smoking risk precedes colon cancer
8. Implication of virus in colon cancer
9. New virtual colonoscopy procedure for easier colon screening
10. Long-term use of calcium supplements to prevent colon cancer
11. Aspirin may reduce he risk of colon cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/20/2017)... ... February 20, 2017 , ... Researchers at the University of Pittsburgh School ... a marker that may predict response to a particular class of drugs, not just ... as well. The new findings were published in Proceedings of the National Academy of ...
(Date:2/20/2017)... ... 20, 2017 , ... Sensogram Technologies Inc., the world leader ... this week at HIMSS 2017 Conference & Exhibition. The event brings more than ... be featured in the conference’s Connected Health Experience section, an area specifically designed ...
(Date:2/20/2017)... Fla. (PRWEB) , ... February 20, 2017 , ... Johns ... research and education building. A topping out ceremony on Friday marked the halfway point ... building, set to open in Fall 2018, will serve as a center for innovation ...
(Date:2/19/2017)... ... , ... The Citadel’s new Swain Department of Nursing , along with ... Ph.D. Joseph was engaged by the college as a consultant to help build the ... a nation-wide search, she was selected to head the department as nurse administrator, assuming ...
(Date:2/19/2017)... ... February 19, 2017 , ... Orbita, ... will join forces with Healthwise ® at HIMSS 2017 to ... leader in evidence-based health education, technology and services, will demonstrate a voice-powered knowedge ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... , Feb. 20, 2017 The report analyzes the worldwide ... comprehensive analytics for the US, Canada , ... Asia-Pacific , Latin America , and Rest ... ... and forecasts are provided for the period 2015 through 2022. Also, ...
(Date:2/20/2017)... 20, 2017  This report analyzes the worldwide markets for ... The report provides separate comprehensive analytics for the US, ... , Europe , Asia-Pacific ... Rest of World. Read the full ... forecasts are provided for the period 2015 through 2022. ...
(Date:2/20/2017)... , Feb. 20, 2017   Orion Health ... Amadeus precision medicine platform to the Amazon ... manages over 110 million patient records globally. ... cloud-based, big data solutions built on modern, scalable technology," ... and Life Sciences. "The AWS Cloud gives healthcare companies ...
Breaking Medicine Technology: