Navigation Links
Risk of Thyroid cancer is increased after Childhood Irradiation of Neck region

Professor Alice Sigurdson and Colleagues has reported the dosage difference which is required for treatment and the dosage which increases the risk of thyroid cancer.

The study was conducted in 72 patients // who were treated for thyroid cancer during their childhood. The thyroid gland which is irradiated during childhood has greater risk of developing thyroid cancer and there seems to be a relationship between radiation and development of oncologic effects. The study documents the evidence of Chernobyl nuclear reactor explosion, in Belarus in which the girls under the age of 14 years who were irradiated by the radiation had a 30 percent more increased risk of thyroid cancer development. Papillary carcinoma was the most common type of cancer which occurs secondary to thyroid cancer.

Thyroid cancer occurrence is an increased secondary malignancy to Childhood Hodgkin’s disease and neuroblastoma. Patients undergoing radiation in the neck regions for treatment of central nervous system cancer, acute lymphoblastic leukemia, Non-Hodgkins lymphoma, Ewing’s sarcoma and Wilm’s tumor develop thyroid cancer. Development of Malignant Hematological diseases is increased in children’s who had whole body irradiation before bone marrow transplantation.

Ron et al, in 1995 had found that the risk of thyroid cancer development increased linearly with increasing doses to the thyroid during thyroid external X-ray or ?-irradiation. The study also reports that dose response relation appeared with the higher doses (>10Gy) associated with cancer therapy. Professor Sigurdson showed that the risk of thyroid cancer increased linearly with increasing therapeutic radiation doses in the low dose range up to 20 Gy, but it demonstrates a downturn in the dose response curve with a declining risk at doses greater than 30 Gy. The risk of thyroid cancer appeared to peak at 20-29 Gy with an odds ration of 9.8. The risk then fell to a low level at doses above 30 Gy. The stu dy shows that widely held belief that lower doses of radiation reduces the late carcinogenic effects does not necessarily apply to the development of thyroid cancer. This point should make us give more thought to our therapeutic strategies that use ionizing radiation in future clinical studies. In view of the long latent interval and the fact that the risk of radiation associated thyroid cancer remains elevated for up to 30 years, the need for long term surveillance, should be monitored with thyroid ultrasonography, for all childhood cancer survivors who had therapeutic radiation of the neck.

Source: The Lance.
'"/>




Related medicine news :

1. Thyroid hormone treatment hastens recovery after cardiac surgery
2. Levothyroxine Thyroid Hormone Replacement, Approved for Hypothyroidism
3. Another Cause of Thyroid Cancer Discovered
4. Common Thyroid Problems In Women May Lower Their Risk Of Developing Breast Cancer
5. Tumour marker for detecting early Recurrence of Thyroid cancer may be soon available
6. Endoscopic Thyroidectomy Helps In Removing Thyroid Cysts
7. Differentiated Thyroid Carcinoma Can Widely Infiltrate The Larynx
8. Chornobyl Incident Proved Increased Risk of Thyroid Cancer from Radioactive Iodine
9. New Study Suggests Perchlorate Effects on Thyroid Function of U.S. Women
10. Levels of Thyroid Hormone Forecasts Life Span
11. Longer-Lived Rodents Have Lower Levels of Thyroid Hormone
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/25/2017)... OK (PRWEB) , ... July 25, 2017 , ... ... proud to announce the launch of their partnership to provide the Pharmacist ... the first pharmacy-focused platform in the country with the ability to develop the ...
(Date:7/25/2017)... ... July 25, 2017 , ... Therachat ... will be exhibiting and providing demos of its smart journaling platform at the ... Center in Washington D.C. from August 3-6, 2017. , The APA Annual Convention ...
(Date:7/25/2017)... , ... July 25, 2017 , ... ... ATM provider in the United States, today announced its partnership with financial technology ... , The foundation of the solution lies within Hyosung’s superior ATMs, assisted ...
(Date:7/25/2017)... Jacksonville, Fla. (PRWEB) , ... July 25, 2017 , ... ... employee and father Ezra Clark is taking advantage of a new benefit for employees ... “It really means a lot that the company supports me and other employees as ...
(Date:7/25/2017)... TX (PRWEB) , ... July 25, 2017 , ... SignatureCare ... emergencies in the Austin, TX area 24 Hours a day. , The ... Austin, TX. , “We’ve been open four months now and things are running ...
Breaking Medicine News(10 mins):
(Date:7/25/2017)... and CAMBRIDGE, Massachusetts , July 25, 2017 ... repurposing drugs to treat rare nervous system diseases, has concluded ... develop and market the drug SOM0226 against transthyretin amyloidosis (ATTR). ... very promising results in a Phase 2 study conducted in ... office in the United States ...
(Date:7/24/2017)... July 24, 2017 IBM (NYSE: IBM ) ... Quadrant for Solid-State Arrays (SSA) for the fourth year in ... According to Gartner, "Vendors in the Leaders quadrant have the ... Vision. A vendor in the Leaders quadrant has the market ... the acceptance of new technologies. These vendors demonstrate a clear ...
(Date:7/21/2017)... EDMONTON, Alberta , July 21, 2017 /PRNewswire/ ... University of Alberta in Edmonton, Canada ... partner journal, Schizophrenia 1 , demonstrating that AI ... schizophrenia with 74% accuracy. This retrospective analysis also ... symptoms in schizophrenia patients with significant correlation, based ...
Breaking Medicine Technology: