Navigation Links
Risk of Thyroid cancer is increased after Childhood Irradiation of Neck region

Professor Alice Sigurdson and Colleagues has reported the dosage difference which is required for treatment and the dosage which increases the risk of thyroid cancer.

The study was conducted in 72 patients // who were treated for thyroid cancer during their childhood. The thyroid gland which is irradiated during childhood has greater risk of developing thyroid cancer and there seems to be a relationship between radiation and development of oncologic effects. The study documents the evidence of Chernobyl nuclear reactor explosion, in Belarus in which the girls under the age of 14 years who were irradiated by the radiation had a 30 percent more increased risk of thyroid cancer development. Papillary carcinoma was the most common type of cancer which occurs secondary to thyroid cancer.

Thyroid cancer occurrence is an increased secondary malignancy to Childhood Hodgkin’s disease and neuroblastoma. Patients undergoing radiation in the neck regions for treatment of central nervous system cancer, acute lymphoblastic leukemia, Non-Hodgkins lymphoma, Ewing’s sarcoma and Wilm’s tumor develop thyroid cancer. Development of Malignant Hematological diseases is increased in children’s who had whole body irradiation before bone marrow transplantation.

Ron et al, in 1995 had found that the risk of thyroid cancer development increased linearly with increasing doses to the thyroid during thyroid external X-ray or ?-irradiation. The study also reports that dose response relation appeared with the higher doses (>10Gy) associated with cancer therapy. Professor Sigurdson showed that the risk of thyroid cancer increased linearly with increasing therapeutic radiation doses in the low dose range up to 20 Gy, but it demonstrates a downturn in the dose response curve with a declining risk at doses greater than 30 Gy. The risk of thyroid cancer appeared to peak at 20-29 Gy with an odds ration of 9.8. The risk then fell to a low level at doses above 30 Gy. The stu dy shows that widely held belief that lower doses of radiation reduces the late carcinogenic effects does not necessarily apply to the development of thyroid cancer. This point should make us give more thought to our therapeutic strategies that use ionizing radiation in future clinical studies. In view of the long latent interval and the fact that the risk of radiation associated thyroid cancer remains elevated for up to 30 years, the need for long term surveillance, should be monitored with thyroid ultrasonography, for all childhood cancer survivors who had therapeutic radiation of the neck.

Source: The Lance.
'"/>




Related medicine news :

1. Thyroid hormone treatment hastens recovery after cardiac surgery
2. Levothyroxine Thyroid Hormone Replacement, Approved for Hypothyroidism
3. Another Cause of Thyroid Cancer Discovered
4. Common Thyroid Problems In Women May Lower Their Risk Of Developing Breast Cancer
5. Tumour marker for detecting early Recurrence of Thyroid cancer may be soon available
6. Endoscopic Thyroidectomy Helps In Removing Thyroid Cysts
7. Differentiated Thyroid Carcinoma Can Widely Infiltrate The Larynx
8. Chornobyl Incident Proved Increased Risk of Thyroid Cancer from Radioactive Iodine
9. New Study Suggests Perchlorate Effects on Thyroid Function of U.S. Women
10. Levels of Thyroid Hormone Forecasts Life Span
11. Longer-Lived Rodents Have Lower Levels of Thyroid Hormone
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... As health professionals work to improve their ... The patient is doing more than filling out a survey; in many cases health ... increasing emphasis in health care and research on the importance of active engagement with ...
(Date:10/13/2017)... ... October 13, 2017 , ... Southern ... and Jennifer Huggins, PharmD ’17, along with clinical associate professor Janice Frueh, ... cardiovascular diseases during the 15th Annual Women’s Health Conference. The SIU School ...
(Date:10/13/2017)... NY (PRWEB) , ... October 13, 2017 , ... Ellevate ... people in business to advocate for action towards gender equality at their inaugural Summit ... from around the globe, and reached a social audience of over 3 million. To ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... 12, 2017 , ... The company has developed a suite ... regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been developed ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... , Sept. 18, 2017 ... fields of bioinformatics and immune engineering, today ... protective avian influenza A (H7N9) vaccine. ... related to seasonal influenza and presents a ... on prior exposure to be effective. Using ...
(Date:9/12/2017)... , Sept. 12, 2017   EcoVadis , the leading platform ... published the first annual edition of its Global CSR Risk and Performance ... evaluated by EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 data ... ... ...
(Date:9/12/2017)...  ValGenesis Inc., the global leader in Enterprise ... announce the appointment of Dr. Ajaz Hussain ... Directors and Chairman of Advisory Board beginning September ... to manage their entire validation lifecycle process electronically ... process. Furthermore, ValGenesis VLMS enables rigorous compliance, helps ...
Breaking Medicine Technology: