Navigation Links
Risk of Thyroid cancer is increased after Childhood Irradiation of Neck region

Professor Alice Sigurdson and Colleagues has reported the dosage difference which is required for treatment and the dosage which increases the risk of thyroid cancer.

The study was conducted in 72 patients // who were treated for thyroid cancer during their childhood. The thyroid gland which is irradiated during childhood has greater risk of developing thyroid cancer and there seems to be a relationship between radiation and development of oncologic effects. The study documents the evidence of Chernobyl nuclear reactor explosion, in Belarus in which the girls under the age of 14 years who were irradiated by the radiation had a 30 percent more increased risk of thyroid cancer development. Papillary carcinoma was the most common type of cancer which occurs secondary to thyroid cancer.

Thyroid cancer occurrence is an increased secondary malignancy to Childhood Hodgkin’s disease and neuroblastoma. Patients undergoing radiation in the neck regions for treatment of central nervous system cancer, acute lymphoblastic leukemia, Non-Hodgkins lymphoma, Ewing’s sarcoma and Wilm’s tumor develop thyroid cancer. Development of Malignant Hematological diseases is increased in children’s who had whole body irradiation before bone marrow transplantation.

Ron et al, in 1995 had found that the risk of thyroid cancer development increased linearly with increasing doses to the thyroid during thyroid external X-ray or ?-irradiation. The study also reports that dose response relation appeared with the higher doses (>10Gy) associated with cancer therapy. Professor Sigurdson showed that the risk of thyroid cancer increased linearly with increasing therapeutic radiation doses in the low dose range up to 20 Gy, but it demonstrates a downturn in the dose response curve with a declining risk at doses greater than 30 Gy. The risk of thyroid cancer appeared to peak at 20-29 Gy with an odds ration of 9.8. The risk then fell to a low level at doses above 30 Gy. The stu dy shows that widely held belief that lower doses of radiation reduces the late carcinogenic effects does not necessarily apply to the development of thyroid cancer. This point should make us give more thought to our therapeutic strategies that use ionizing radiation in future clinical studies. In view of the long latent interval and the fact that the risk of radiation associated thyroid cancer remains elevated for up to 30 years, the need for long term surveillance, should be monitored with thyroid ultrasonography, for all childhood cancer survivors who had therapeutic radiation of the neck.

Source: The Lance.

Related medicine news :

1. Thyroid hormone treatment hastens recovery after cardiac surgery
2. Levothyroxine Thyroid Hormone Replacement, Approved for Hypothyroidism
3. Another Cause of Thyroid Cancer Discovered
4. Common Thyroid Problems In Women May Lower Their Risk Of Developing Breast Cancer
5. Tumour marker for detecting early Recurrence of Thyroid cancer may be soon available
6. Endoscopic Thyroidectomy Helps In Removing Thyroid Cysts
7. Differentiated Thyroid Carcinoma Can Widely Infiltrate The Larynx
8. Chornobyl Incident Proved Increased Risk of Thyroid Cancer from Radioactive Iodine
9. New Study Suggests Perchlorate Effects on Thyroid Function of U.S. Women
10. Levels of Thyroid Hormone Forecasts Life Span
11. Longer-Lived Rodents Have Lower Levels of Thyroid Hormone
Post Your Comments:

(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , ... Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , ... our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San ... Society and the Road To Recovery® program to drive cancer patients to and from ... adults to ensure the highest quality of life and ongoing independence. Getting to ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty Network, affiliated ... Weintraub as a prominent plastic surgeon and the network’s newest partner. , ... most handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Any dentist who has made an implant ... process. Many of them do not even offer this as ... high laboratory costs involved. And those who ARE able to ... a high cost that the majority of today,s patients would ... Parsa Zadeh , founder of Dental Evolutions Inc. and inventor ...
(Date:6/23/2016)... LOS ANGELES , June 23, 2016 /PRNewswire/ ... (NASDAQ: CAPR ), a biotechnology company ... first-in-class therapeutics, today announced that patient enrollment in ... progrEssion in Duchenne) has exceeded 50% of its ... its enrollment in the third quarter of 2016, ...
(Date:6/23/2016)... the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in Bogota. Colombia ... ... Sandra ... ... Astellas is a pharmaceutical company ...
Breaking Medicine Technology: