Navigation Links
Risk of Thyroid cancer is increased after Childhood Irradiation of Neck region

Professor Alice Sigurdson and Colleagues has reported the dosage difference which is required for treatment and the dosage which increases the risk of thyroid cancer.

The study was conducted in 72 patients // who were treated for thyroid cancer during their childhood. The thyroid gland which is irradiated during childhood has greater risk of developing thyroid cancer and there seems to be a relationship between radiation and development of oncologic effects. The study documents the evidence of Chernobyl nuclear reactor explosion, in Belarus in which the girls under the age of 14 years who were irradiated by the radiation had a 30 percent more increased risk of thyroid cancer development. Papillary carcinoma was the most common type of cancer which occurs secondary to thyroid cancer.

Thyroid cancer occurrence is an increased secondary malignancy to Childhood Hodgkin’s disease and neuroblastoma. Patients undergoing radiation in the neck regions for treatment of central nervous system cancer, acute lymphoblastic leukemia, Non-Hodgkins lymphoma, Ewing’s sarcoma and Wilm’s tumor develop thyroid cancer. Development of Malignant Hematological diseases is increased in children’s who had whole body irradiation before bone marrow transplantation.

Ron et al, in 1995 had found that the risk of thyroid cancer development increased linearly with increasing doses to the thyroid during thyroid external X-ray or ?-irradiation. The study also reports that dose response relation appeared with the higher doses (>10Gy) associated with cancer therapy. Professor Sigurdson showed that the risk of thyroid cancer increased linearly with increasing therapeutic radiation doses in the low dose range up to 20 Gy, but it demonstrates a downturn in the dose response curve with a declining risk at doses greater than 30 Gy. The risk of thyroid cancer appeared to peak at 20-29 Gy with an odds ration of 9.8. The risk then fell to a low level at doses above 30 Gy. The stu dy shows that widely held belief that lower doses of radiation reduces the late carcinogenic effects does not necessarily apply to the development of thyroid cancer. This point should make us give more thought to our therapeutic strategies that use ionizing radiation in future clinical studies. In view of the long latent interval and the fact that the risk of radiation associated thyroid cancer remains elevated for up to 30 years, the need for long term surveillance, should be monitored with thyroid ultrasonography, for all childhood cancer survivors who had therapeutic radiation of the neck.

Source: The Lance.
'"/>




Related medicine news :

1. Thyroid hormone treatment hastens recovery after cardiac surgery
2. Levothyroxine Thyroid Hormone Replacement, Approved for Hypothyroidism
3. Another Cause of Thyroid Cancer Discovered
4. Common Thyroid Problems In Women May Lower Their Risk Of Developing Breast Cancer
5. Tumour marker for detecting early Recurrence of Thyroid cancer may be soon available
6. Endoscopic Thyroidectomy Helps In Removing Thyroid Cysts
7. Differentiated Thyroid Carcinoma Can Widely Infiltrate The Larynx
8. Chornobyl Incident Proved Increased Risk of Thyroid Cancer from Radioactive Iodine
9. New Study Suggests Perchlorate Effects on Thyroid Function of U.S. Women
10. Levels of Thyroid Hormone Forecasts Life Span
11. Longer-Lived Rodents Have Lower Levels of Thyroid Hormone
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... Orion, Clarkston, Michigan (PRWEB) , ... June 26, ... ... with respect to fertility once they have been diagnosed with endometriosis. These women ... intercourse but they also require a comprehensive approach that can help for preservation ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding ... of its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. ... James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. ...
(Date:6/24/2016)... ... ... A recent article published June 14 on E Online details ... to state that individuals are now more comfortable seeking to undergo not only the ... and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) notes ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. ... The attorneys chosen by their peers for this recognition are considered among the top ... Shareholders received special honors as members of this year’s Legal Elite Hall of Fame: ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine presented ... in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor the ... Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With this award, ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... One of Australia,s successful biotechnology ... a new biotechnology company, Noxopharm Limited [ABN 50 608 966 123] ... to list on the ASX. Noxopharm is a clinic-ready ... a Phase 1 clinical study later this year. ... the biggest problems facing cancer patients - the ability of cancers ...
(Date:6/26/2016)... Jazz Pharmaceuticals plc (Nasdaq: JAZZ ... Antitrust Improvements Act of 1976, as amended ("HSR"), with ... ("Celator"; Nasdaq: CPXX ) expired effective June ... As previously announced on May 31, 2016, Jazz ... under which Jazz Pharmaceuticals has commenced a tender offer ...
(Date:6/26/2016)... OTTAWA, Ontario , June 27, 2016  VMS ... the Company,s Board will take whatever measures required to ... the Company,s stock which is currently listed on the ... S Wexler, Company Chairman and CEO, "We are seeing ... be difficult to understand, not only by the Company, ...
Breaking Medicine Technology: