Navigation Links
Risk of Bladder Cancer Reduced by Broccoli and Cauliflower

A recent research has found that intake of cruciferous vegetables with a high content of isothiocyanates may offer a protective benefit against bladder cancer.

Isothiocyanates (ITC) are compounds found in cruciferous vegetables such as broccoli, cauliflower, kale, turnips, collards, Brussels sprouts, cabbage, radish, turnip and watercress.

They apply their anti-oxidant effect through down regulation of cytochrome p450 enzyme levels and provoke apoptosis by triggering Phase II detoxifying enzymes. Experimental data has recommended that these compounds may protect against the origins of bladder cancer.

In the May 15th issue of the International Journal of Cancer, Zhao and colleagues from the Departments of Epidemiology and Urology at the M.D. Anderson Cancer Center report on an epidemiological study assessing the connection between ITC consumption and bladder cancer risk.

The group included 697 patients with recently diagnosed bladder cancer and 708 healthy controls matched by age, sex, and race. The participants were asked to complete a dietary questionnaire, following which the intake of ITCs was compared with bladder cancer risk and with the expression of genetic polymorphisms for the arylamine N-acetyltransferases 2 (NAT) and glutathione S-transferase genes.

Average ITC intake per day was considerably lower in bladder cancer patients than in controls (0.23 vs. 0.33, p < 0.001). High ITC intake was linked to 29% lower risk of bladder cancer (odds ratio = 0.71, 95% CI 0.57 to 0.89). This anti-cancer effect was seen more frequently in men, in patients age 64 or older, and in smokers.

NAT2 slow acetylators displayed an augmented risk of bladder cancer in Caucasians compared with rapid acetylators (OR = 1.31, 95% CI 1.02 to 1.69). The decrease in bladder cancer risk associated with ITC intake was not associated to NAT2, GSTM1, or GSTT1 genotype expression.

This well-co nducted study for the first time exhibits that eating cruciferous vegetables with a high content of isothiocyanates such as broccoli, cauliflower, kale, turnips, collards, Brussels sprouts, cabbage, radish, turnip and watercress is associated with a decreased risk of bladder cancer.


'"/>




Related medicine news :

1. Chemotherapy Effective for Bladder Cancer
2. Dogs Can Sense Bladder Cancer
3. More Causes of Bladder Cancer Identified
4. More Dependable Screening Test For Bladder Cancer
5. Marijuana-Derived Drug Promises Hope In Treating Bladder Infection
6. Shy Bladder Syndrome: A Social Phobia Or Functional Disorder Of Micturition?
7. Coaching In Labor Could Increase Bladder Problems
8. Measuring Urinary Protein Helps In Detecting Recurrent Bladder Cancer
9. Brain holds the key to Overactive Bladder
10. Smoking Marijuana Increases The Risk Of Bladder Cancer
11. Bladder Surgery Patients Warned About Risk Of Bladder Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/24/2017)... ... February 24, 2017 , ... The narrative in “ Signal 8: An Australian ... account of his paramedic experiences. Schanssema describes the tragedies he saw, as well as ... overcome them. , Schanssema, initially unsure of the career path he wanted to take, ...
(Date:2/24/2017)... ... , ... The International Association of Eating Disorders Professionals (iaedp) announces the 2017 ... image mannequin art competition. Selected from 15 submissions from around the nation, the top ... 31st annual iaedp Symposium, March 22 – 26 in Las Vegas. , This year, ...
(Date:2/24/2017)... ... February 24, 2017 , ... Congratulations ... International Elite division on February 12th. Ms. Esparza qualified into this prestigious ... qualifier competition held in Las Vegas, Nevada. Frida is one of approximately 25 ...
(Date:2/23/2017)... ... February 23, 2017 , ... The 89th Academy Awards will be celebrated ... National Education Policy Center Bunkum Award. We invite you to enjoy our 11th annual ... Bunkum winner is the Center for American Progress (CAP), for its report, Lessons From ...
(Date:2/23/2017)... ... February 23, 2017 , ... Los Angeles-based weight loss surgeon Michael Feiz, ... June: From Not to Hot,” which will begin airing on February 24, 2017. The ... millions from the 2012 reality television series, “Here Comes Honey Boo Boo.” The earlier ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... Research and Markets has announced the addition of the "Global ... report to their offering. ... The Global Empty Capsules Market is poised to grow at a CAGR ... by 2025. This industry report analyzes the market estimates ... regional levels presented in the research scope. The study provides historical market ...
(Date:2/24/2017)... , Feb. 24, 2017  In conjunction with ... 2016 financial results press release, you are invited to ... live over the internet on Tuesday, March 14, 2017 ... A live audio webcast of the presentation ... www.durect.com and clicking "Investor Relations."  If you are ...
(Date:2/24/2017)... Feb. 23, 2017 Report analyzes the worldwide markets ... comprehensive analytics for the US, Canada , ... Asia-Pacific , Latin America ... provided for the period 2015 through 2022. Also, a six-year ... analytics are derived from primary and secondary research. Company profiles ...
Breaking Medicine Technology: