Navigation Links
Risk of Bladder Cancer Reduced by Broccoli and Cauliflower

A recent research has found that intake of cruciferous vegetables with a high content of isothiocyanates may offer a protective benefit against bladder cancer.

Isothiocyanates (ITC) are compounds found in cruciferous vegetables such as broccoli, cauliflower, kale, turnips, collards, Brussels sprouts, cabbage, radish, turnip and watercress.

They apply their anti-oxidant effect through down regulation of cytochrome p450 enzyme levels and provoke apoptosis by triggering Phase II detoxifying enzymes. Experimental data has recommended that these compounds may protect against the origins of bladder cancer.

In the May 15th issue of the International Journal of Cancer, Zhao and colleagues from the Departments of Epidemiology and Urology at the M.D. Anderson Cancer Center report on an epidemiological study assessing the connection between ITC consumption and bladder cancer risk.

The group included 697 patients with recently diagnosed bladder cancer and 708 healthy controls matched by age, sex, and race. The participants were asked to complete a dietary questionnaire, following which the intake of ITCs was compared with bladder cancer risk and with the expression of genetic polymorphisms for the arylamine N-acetyltransferases 2 (NAT) and glutathione S-transferase genes.

Average ITC intake per day was considerably lower in bladder cancer patients than in controls (0.23 vs. 0.33, p < 0.001). High ITC intake was linked to 29% lower risk of bladder cancer (odds ratio = 0.71, 95% CI 0.57 to 0.89). This anti-cancer effect was seen more frequently in men, in patients age 64 or older, and in smokers.

NAT2 slow acetylators displayed an augmented risk of bladder cancer in Caucasians compared with rapid acetylators (OR = 1.31, 95% CI 1.02 to 1.69). The decrease in bladder cancer risk associated with ITC intake was not associated to NAT2, GSTM1, or GSTT1 genotype expression.

This well-co nducted study for the first time exhibits that eating cruciferous vegetables with a high content of isothiocyanates such as broccoli, cauliflower, kale, turnips, collards, Brussels sprouts, cabbage, radish, turnip and watercress is associated with a decreased risk of bladder cancer.


'"/>




Related medicine news :

1. Chemotherapy Effective for Bladder Cancer
2. Dogs Can Sense Bladder Cancer
3. More Causes of Bladder Cancer Identified
4. More Dependable Screening Test For Bladder Cancer
5. Marijuana-Derived Drug Promises Hope In Treating Bladder Infection
6. Shy Bladder Syndrome: A Social Phobia Or Functional Disorder Of Micturition?
7. Coaching In Labor Could Increase Bladder Problems
8. Measuring Urinary Protein Helps In Detecting Recurrent Bladder Cancer
9. Brain holds the key to Overactive Bladder
10. Smoking Marijuana Increases The Risk Of Bladder Cancer
11. Bladder Surgery Patients Warned About Risk Of Bladder Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... ... Ellevate Network, the leading network for professional women, brought together some of ... their inaugural Summit in New York City in June. The event was livestreamed with ... 3 million. To watch the Mobilize Women video, click here . , ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer ... one of the most popular and least understood books in the Holy Scriptures, Revelation. ... descriptions that have baffled scholars for centuries. Many have tossed it off as mere ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian history ... The Brink” is the creation of published author, William Nowers. Captain Nowers and ... WWII veteran, he spent thirty years in the Navy. Following his career as ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and ... apnea using cutting-edge Oventus O2Vent technology. As many as 18 million Americans ... frequent cessation in breathing. Oral appliances can offer significant relief to about 75 ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)...   Montrium , an industry leader in ... IQPC Trial Master Files & Inspection Readiness Conference ... Clinical Services has selected eTMF Connect ... EastHORN, a leading European contract research organization (CRO), ... to enable greater collaboration with sponsors, improve compliance ...
(Date:9/22/2017)... -- AVACEN Medical (AVACEN) announced that its CE-Marked AVACEN ... with the widespread pain associated with fibromyalgia in the ... Essex, England commented, "I had difficulty ... sleep at all, tremendous pain, with every movement sending ... AVACEN 100] enough, how this has and is helping ...
(Date:9/18/2017)... Sept. 18, 2017 EpiVax, Inc. ... bioinformatics and immune engineering, today announced a ... A (H7N9) vaccine. ... seasonal influenza and presents a challenge for ... exposure to be effective. Using state-of-the-art bioinformatics and ...
Breaking Medicine Technology: