Navigation Links
Risk Of Birth Defects Increased Due To Anti-Depressant Medication

A warning has been issued to all physicians, more specifically to pregnant women against the prescription and consumption of Paxil, given for treatment of depression due to the risk of increased congenital// heart defects in newborns.

The notice has been issued by the Food and Drug Administration (FDA) and is based on early findings of two studies, which had demonstrated that women who took Paxil during the first trimester had a two fold increased risk of giving rise to babies with congenital heart defects compared to other pregnant women. The risk of birth defect was significantly higher compared to pregnant women who took other forms of anti-depressant medication.

In the studies cited by the FDA, the risk of congenital heart defects is about 1 percent overall, which rose to 1.5 to 2 percent in infants born to women taking Paxil. Following the notification, the drug has been placed in the second highest category for risk of birth defects. It is generally advisable to avoid all drugs during pregnancy. However in case use of an anti-depressant medication is very necessary, it is safer to use other medicines as a substitute after a careful consultation with the physician.

The physicians have also been alerted regarding the adverse effects arising out of sudden withdrawal of Paxil. Though it was known that selective serotonin reuptake inhibitors (SSRIs) could harm fetuses, the magnitude of the risk has not been studied previously. The recent report by the FDA and GlaxoSmithKline (manufacturer of Paxil) is the only strong evidence that it can result in birth defects.

Approximately 20% of all pregnant women are estimated to suffer from some form of depression. This creates confusion about the initiation and continuation of anti-depressant medication in pregnancy. The increased tendency of pregnant women to display irritable behaviour, tremors and seizures following childbirth has posed additional concerns regarding mother’s healt h.

Ever since the time of approval in 1993, the drug has been taken by over millions worldwide. Women of childbearing age (18-45 yrs) constitute 25% of the total number of Paxil users. Although several studies have demonstrated the effectiveness of Paxil in the treatment of depression, anxiety disorder and other psychiatric disorders in adults, the data available on the safe use of Paxil is very limited.

Keeping in mind the above figure, it is high time that certain guidelines are formulated regarding usage of Paxil. Ultimately, the gold standard rule of benefit Vs risk should dictate the indication for use under all circumstances including pregnancy.

Related medicine news :

1. Birth weight key factor in heart diseases
2. FDA Approves Birth Control Skin Patch
3. IVF technique May Increase The Risk Of Birth Defects
4. Smoking Linked To Low Infant Birth Weight
5. Unpredictable Premature Birth
6. New Birth Control Pills increase the stroke risk
7. Epilepsy Drugs Can Enhance Risk of Birth Defects
8. Sex timing has no impact on risk of Birth defects
9. Birth weight may be influenced by genes
10. Dental Procedure Reduces Preterm Births
11. Low Birth Weight infants could have Problems in the Future
Post Your Comments:

(Date:6/27/2016)... ... June 27, 2016 , ... TherapySites, ... its affiliation with Tennessee Counseling Association. This new relationship allows TherapySites ... Tennessee Counseling Association, adding exclusive benefits and promotional offers. , "TCA is extremely ...
(Date:6/26/2016)... , ... June 27, 2016 , ... Quality metrics are ... in many ways they remain in the eye of the beholder, according to experts ... publication of The American Journal of Managed Care. For the full issue, click ...
(Date:6/26/2016)... ... , ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop a ... fitness app plans to fix the two major problems leading the fitness industry today:, ... type program , They don’t eliminate all the reasons people quit their exercise ...
(Date:6/25/2016)... ... ... closing of Bruton Memorial Library on June 21 due to a possible lice infestation, as ... of head lice: the parasite’s ability to live away from a human host, and to ... one in the event that lice have simply gotten out of control. , As lice ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
(Date:6/23/2016)... and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma ... as the company,s second affiliate in Latin America . ... ... Astellas Farma Colombia ... ...
(Date:6/23/2016)... 23, 2016  Guerbet announced today that it has ... Horizon Award . One of 12 suppliers ... for its support of Premier members through exceptional local ... and commitment to lower costs. ... of our outstanding customer service from Premier," says ...
Breaking Medicine Technology: