Navigation Links
Risk Of Birth Defects Increased Due To Anti-Depressant Medication

A warning has been issued to all physicians, more specifically to pregnant women against the prescription and consumption of Paxil, given for treatment of depression due to the risk of increased congenital// heart defects in newborns.

The notice has been issued by the Food and Drug Administration (FDA) and is based on early findings of two studies, which had demonstrated that women who took Paxil during the first trimester had a two fold increased risk of giving rise to babies with congenital heart defects compared to other pregnant women. The risk of birth defect was significantly higher compared to pregnant women who took other forms of anti-depressant medication.

In the studies cited by the FDA, the risk of congenital heart defects is about 1 percent overall, which rose to 1.5 to 2 percent in infants born to women taking Paxil. Following the notification, the drug has been placed in the second highest category for risk of birth defects. It is generally advisable to avoid all drugs during pregnancy. However in case use of an anti-depressant medication is very necessary, it is safer to use other medicines as a substitute after a careful consultation with the physician.

The physicians have also been alerted regarding the adverse effects arising out of sudden withdrawal of Paxil. Though it was known that selective serotonin reuptake inhibitors (SSRIs) could harm fetuses, the magnitude of the risk has not been studied previously. The recent report by the FDA and GlaxoSmithKline (manufacturer of Paxil) is the only strong evidence that it can result in birth defects.

Approximately 20% of all pregnant women are estimated to suffer from some form of depression. This creates confusion about the initiation and continuation of anti-depressant medication in pregnancy. The increased tendency of pregnant women to display irritable behaviour, tremors and seizures following childbirth has posed additional concerns regarding mother’s healt h.

Ever since the time of approval in 1993, the drug has been taken by over millions worldwide. Women of childbearing age (18-45 yrs) constitute 25% of the total number of Paxil users. Although several studies have demonstrated the effectiveness of Paxil in the treatment of depression, anxiety disorder and other psychiatric disorders in adults, the data available on the safe use of Paxil is very limited.

Keeping in mind the above figure, it is high time that certain guidelines are formulated regarding usage of Paxil. Ultimately, the gold standard rule of benefit Vs risk should dictate the indication for use under all circumstances including pregnancy.
'"/>




Related medicine news :

1. Birth weight key factor in heart diseases
2. FDA Approves Birth Control Skin Patch
3. IVF technique May Increase The Risk Of Birth Defects
4. Smoking Linked To Low Infant Birth Weight
5. Unpredictable Premature Birth
6. New Birth Control Pills increase the stroke risk
7. Epilepsy Drugs Can Enhance Risk of Birth Defects
8. Sex timing has no impact on risk of Birth defects
9. Birth weight may be influenced by genes
10. Dental Procedure Reduces Preterm Births
11. Low Birth Weight infants could have Problems in the Future
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson Insurance and Financial ... financial preparation services, is providing an update on a charitable event that began ... Rescue is a locally recognized nonprofit that provides shelter and care for animals ...
(Date:10/13/2017)... ... ... PurhealthRX , a leading Health and Nutrition Company, is announcing the ... spectrum CBD oil will revolutionize the rapidly growing CBD market by reducing the amount ... into liquid products, while reducing costs to end users. , The team of researchers ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association ... Featuring a collection of specialty vendors and unique items from across the nation, this ... health and wellness services offered by the VNA. The boutique will be open ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Agile Software Development, has been awarded a contract by the Center for Medicare ... (BPA) aims to accelerate the enterprise use of Agile methodologies in a consistent ...
(Date:10/12/2017)... , ... October 12, 2017 , ... Planet Fitness, one ... U.S., announced today its plans to open a flagship location in Covington, LA at ... former Rooms To Go store next to Office Depot in the Holiday Square shopping ...
Breaking Medicine News(10 mins):
(Date:9/13/2017)... --  OrthoAtlanta has been named the official orthopedic and ... for the 2018 College Football Playoff (CFP) National Championship to ... in Atlanta, Georgia . OrthoAtlanta is proud ... participating in many activities leading up to, and including the ... ...
(Date:9/12/2017)... , Sept. 12, 2017  Consumer reviews on the independent ... as the number one company for hearing aids, ranking it ... fifteen other brands. ... Hearing Named #1 by Consumers For Hearing Aids ... Embrace Hearing is an online store that provides high performance, ...
(Date:9/9/2017)... 2017 ... coming to Washington DC ... Tuesday, September 12 th – Monday, September 18 th .The Brain ... MRI brain scans to the public.Where:  BTF,s Mobile ... 501 K Street NW, Washington, D.C.What:BTF brings its nationwide initiative, the Road ...
Breaking Medicine Technology: