Navigation Links
Risk Factors for Rheumatoid Arthritis

A new study sheds light on the role of environmental and genetic risk factors in the development of rheumatoid arthritis (RA). A team of researchers in Sweden have identified smoking, a low formal level of education and certain metabolic indicators as important risk factors in the development of RA.

These findings represent a significant step towards better understanding of the risk factors for RA and may contribute to improved future prevention and treatment of this debilitating disease.

The first study showed that smoking (odds ratio 1.77; 95% confidence interval 1.13 to 2.78) and a low level of formal education, such as elementary school education only versus university degree status (odds ratio 2.46 confidence interval 1.20 to 5.02), may independently increase the risk of developing RA.

The second study similarly highlights the link between of smoking and RA but, contrary to previously noted relationships between RA with active inflammation and impaired glucose tolerance, observes better glucose tolerance as a predictor of RA.

In the multivariate model, a lower glucose level at 120 minutes after an oral glucose tolerance test (odds ratio 1.19 per mmol/L; confidence interval 1.04 to 1.35) and smoking (odds ratio 1.64; confidence interval 1.08 to 2.48) were both found to be independent predictors of RA. Thus the authors suggest that factors such as diet and genetics influencing metabolism may play an important part in RA development.

Dr Ulf Bergstrom from the Malm University Hospital, Sweden, lead investigator on both studies said, The determinants for developing RA in any population are clearly complex and often unrelated. These studies help us to add more pieces to the giant jigsaw of risk factors for one of the most common autoimmune diseases, affecting approximately 1% of adults worldwide.

We hope these findings will contribute to better understanding of future RA prevention and treatment. Whilst the glucose tolerance findings contrast with previous studies linking impaired tolerance to established RA, they suggest that other mechanisms may be important years before RA onset. Our results will pave the way for future debate and research to pinpoint its definitive causes.

research to pinpoint its definitive causes.

The two studies involved people enrolled in the Malmo Diet and Cancer Study (MDCS) (n=30,447) between 1991 and 1996 and a Preventive Medicine Program (PMP) (n=33,346) between 1974 and 1992.

Investigators examined lifestyle factors using a self-administered questionnaire and glucose tolerance and lipids readings were taken by health professionals. Individuals who developed RA after participation in the health surveys were compared to controls without RA from the PMP and MDCS, matched for age, sex and year of screening.


'"/>




Related medicine news :

1. Risk Factors for vision problems in Diabetes
2. Age-Related Macular Degeneration - Risk Factors
3. Factors That Might Increase The Risk Of Schizophrenia
4. Evaluating The Risk Factors Of Osteoporosis
5. Risk Factors For Stroke Studied
6. Analyzing The Risk Factors For Diabetic Neuropathy
7. Heart Disease Risk Factors Found To Increase Risk of Dementia In Old Age
8. Environmental Factors Found To Have An Impact On The Sex of A Child
9. Environmental Factors Found To Have An Impact On The Sex of A Child
10. Prostate Cancer Test Is Influenced By Age and Nutrition Factors
11. Youth Smoking Sparked By Multiple Factors: Study
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... As health professionals work to improve their approach ... patient is doing more than filling out a survey; in many cases health professionals ... emphasis in health care and research on the importance of active engagement with patients ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor ... prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. The ...
(Date:10/13/2017)... NY (PRWEB) , ... October 13, 2017 , ... Ellevate ... people in business to advocate for action towards gender equality at their inaugural Summit ... from around the globe, and reached a social audience of over 3 million. To ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “The Journey: From ... every danger possible to save lost souls in the Philippines. “The Journey: From the ... is a dedicated teacher of the Bible. She has taught all ages and currently ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has ... today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula ... the highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... Mich. , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company ... destruction of targeted tissues, announced three leadership team developments today:   ... PhD ... ... Veteran medical device executive Josh ...
(Date:9/18/2017)... , Sept. 18, 2017  PMD Healthcare of ... Pharmacy of Kalamazoo, Mich. , have ... service that expedites and streamlines patient and provider access ... 2.0, and wellness management services.  ... used to measure lung function for a variety of ...
(Date:9/13/2017)... OrthoAtlanta has been named the official orthopedic and sports ... the 2018 College Football Playoff (CFP) National Championship to be ... Atlanta, Georgia . OrthoAtlanta is proud to ... in many activities leading up to, and including the national ... OrthoAtlanta ...
Breaking Medicine Technology: