Navigation Links
Right Foods Could Improve Drug Effectiveness, Lower Drug Costs

Combining medicines with the right food could improve the effectiveness of drugs and dramatically lower the rapidly rising costs of treating patients, experts say .

University of Chicago oncologists Mark Ratain, MD, and Ezra Cohen, MD, have released their expert comments after examining research that showed taking a breast cancer drug with fatty food, rather than on an empty stomach, enhanced absorption of the drug.

Previously experts have warned of the potential dangers of interactions between food and drugs i.e. they could lead to drugs becoming toxic, or less effective.

But Ratain and Cohen argue that results like this one should point researchers toward a partial solution, a novel way to decrease medication costs while increasing benefits from these effective but expensive drugs.

The study found that taking the drug with a meal increased the bioavailability of the drug by 167 percent. Taking the drug with a high-fat meal boosted levels by 325 percent.

"Simply by changing the timing, taking this medication with a meal instead of on an empty stomach, we could potentially use 40 percent (or even less) of the drug. Since lapatinib costs about $2,900 a month, this could save each patient $1,740 or more a month, Ratain said.

He added that drinking grapefruit juice, which is known to boost the rate at which some drugs enter the blood stream, at the same time could increase these savings to 80 percent.

"We expect the one 250 mg lapatinib pill accompanied by food and washed down with a glass of grapefruit juice may yield plasma concentrations comparable to five 250 mg pills on an empty stomach," Ratain said.

And eating such "value meals" at the same time as taking drugs could have other benefits too, the authors add.

For example, the major toxicity associated with lapatinib is diarrhea, probably caused by unabsorbed drug. So taking a lower dose with food should "reduce the amount of unabsorbed drug, and therefore theoretically also reduce the frequency and severity of diarrhea."

But the authors warned patients against trying these experiments on their own, calling instead for more research to gauge the effects of drug-combinations on patients.

"The one thing that should not be anticipated is an efficacy study by lapatinib's sponsor," the authors write.

They are currently conducting such a study of their own, testing the consequence of combining a drug with grapefruit juice, and have called for more such studies to be carried out.


'"/>




Related medicine news :

1. Right drugs drastically cut stroke risk
2. Right side of the brain helps in awareness
3. Right attitude makes you benefit from exercise
4. Stroke In The Right-Brain Can Remain Undiagnosed
5. Want Strong Bones: Exercise And Eat Right!
6. Govt Keen To Propagate Stem Cell Research On Right Track
7. Mummy Is Always Right: Nurses Research Prove It Over Again
8. Doctors Ask MPs To Protect Human Rights By Banning Smoking In Enclosed Public Spaces
9. Will Teflon Regain Its Rightful Place In The Kitchen?
10. Equal Rights for HIV Infected Workers
11. Braces Work Wonders In Setting Crooked Teeth Right
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/21/2017)... (PRWEB) , ... July 21, 2017 , ... ... management assistance and financial planning services to families and business owners in northern ... event that promises to provide support to area adults with developmental challenges. , ...
(Date:7/21/2017)... ... July 21, 2017 , ... ... selected to renovate and improve the Ramsey County Medical Examiners Facility located in ... Hospital, the $2.5 million project is scheduled to start in late 2017/early 2018. ...
(Date:7/21/2017)... , ... July 21, 2017 , ... ... and Theater of Witness , was awarded a $300,000 grant from ... program which fosters empathy, comfort with ambiguity and the recognition of one’s own ...
(Date:7/21/2017)... ... 2017 , ... Bernard R. Bach, Jr., MD, orthopaedic surgeon at Rush University ... of Sports Medicine (AOSSM) , received the 2017 Robert E. Leach Sports Medicine Leadership ... This prestigious award is given annually to honor those who have made a significant ...
(Date:7/21/2017)... ... July 21, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... of violence and aggression to solve problems and pleads with world leaders to be more ... forces do not bring peace. He says there is a peaceful and positive way to ...
Breaking Medicine News(10 mins):
(Date:7/10/2017)... 2017  BDI Group subsidiary Pathway Purchasing Network, ... organization serving specialty pharmacies, home infusion companies and ... significant, value-added member programs designed to help organizations ... and improve access and affordability for patients who ... Pathway has worked ...
(Date:7/10/2017)... , July 10, 2017 Locus Biosciences ... Note to support the development of CRISPR-Cas3 antimicrobial therapeutics. ... Limited, a leading Chinese Internet services provider, and joined ... advance multiple infectious disease product programs targeting antibiotic resistant ... Founded by Dr. Rodolphe Barrangou ...
(Date:7/5/2017)... , July 5, 2017 Wolfmet 3D ... answer as physics and manufacturing combine to progress molecular radiotherapy ... existing SPECT systems are unable to accurately quantify the radiation ... limited information regarding the success of this radiotherapy treatment has ... ...
Breaking Medicine Technology: