Navigation Links
Researchers Looking for Genes That Control the Brain

Although it’s our most vital organ, surprisingly little is known about what constitutes a ‘normal’ brain. That makes it harder to uncover what’s gone awry in people suffering// from mental illness and other brain-associated disorders, and ultimately, it often leaves physicians treating symptoms rather than causes of conditions such as Alzheimer’s and Parkinson’s disease, schizophrenia, attention deficit hyperactivity disorder (ADHD), and many other ailments.

That’s why researchers from two San Antonio institutions have combined forces for the largest study of its kind to map out normal variations in brain structure and function and identify the genes responsible for those variations. They expect their five-year investigation – funded with two new cooperative grants totaling $7 million from the National Institute of Mental Health – to yield a host of new data on basic brain biology and mental illnesses, as well as spawn additional studies focusing on specific diseases.

Why study what’s ‘normal’? Because scientists have not developed a good understanding of basic brain biology and the role of genes, they do not know the root causes of most mental disorders, said geneticist John Blangero, Ph.D., of the Southwest Foundation for Biomedical Research, who is leading the study with David Glahn, Ph.D., psychologist and associate professor at the University of Texas Health Science Center at San Antonio.

To get to the heart of the matter, Blangero and Glahn are taking a different approach from many previous studies of the brain. Rather than looking for research subjects suffering from a particular mental illness and studying differences in their brain structure and function, this research team is working with large family groups from the average population to better understand normal brain variation and the genes that control it.

‘We want to inform aspects of brain biology that are relevant for a lot of different diseases,’ Blangero said. ‘That’s why we’re not focused on any disease. We’re focused on finding the genes that influence normal brain variation. Those are going to be the same genes that also influence pathological variations.’

‘This gives us the potential to evolve some of the basic questions that we’re constantly dealing with from the side of neurologic and psychiatric illness, research areas where it’s difficult to gain traction when you’re focused on the disease itself,’ explained Glahn. ‘This is because the things we’re interested in -- be they cognition, brain structure or brain physiology – are changed dramatically in people with mental illness. So we [in the psychiatric community] are constantly questioning, ‘Is this change [in the brain] a cause of the illness? A result of the illness? A result of treatment of the illness?’ By studying the biology of the brain in healthy subjects, we’ll be able to overcome the ‘chicken-and-egg’ problem that’s constantly there in clinical research.’

Source-Newswise
SRM
'"/>




Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin ... injury. Recently, he has implemented orthobiologic procedures as a method for treating his ... of the first doctors to perform the treatment. Orthobiologics are substances that orthopaedic ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether ... latter, setting the bar too high can result in disappointment, perhaps even self-loathing. However, ... their goal. , Research from PsychTests.com reveals that behind the tendency ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
(Date:6/24/2016)... ... ... Marcy was in a crisis. Her son James, eight, was out of control. Prone to ... , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there ... my other children and say he was going to kill them. If we were ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Global law firm ... 2016 Legal Elite. The attorneys chosen by their peers for this recognition are considered ... Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal Elite ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- Dehaier Medical Systems Ltd. (NASDAQ: DHRM ... sells medical devices and wearable sleep respiratory products in ... agreement with Hongyuan Supply Chain Management Co., Ltd. (hereinafter ... 2016, to develop Dehaier,s new Internet medical technology business. ... leverage Hongyuan Supply Chain,s sales platform to reach Dehaier,s ...
(Date:6/24/2016)... -- Research and Markets has announced the addition ... report to their offering. ... The World Market for Companion Diagnostics covers the world ... in the report includes the following: , ... by Region (N. America, EU, ROW), 2015-2020 , World ...
(Date:6/24/2016)...   Pulmatrix, Inc ., (NASDAQ: PULM ... announced today that it was added to the Russell ... comprehensive set of U.S. and global equity indexes on ... milestone for Pulmatrix," said Chief Executive Officer Robert ... progress in developing drugs for crucial unmet medical needs, ...
Breaking Medicine Technology: