Navigation Links
Researchers Looking for Genes That Control the Brain

Although it’s our most vital organ, surprisingly little is known about what constitutes a ‘normal’ brain. That makes it harder to uncover what’s gone awry in people suffering// from mental illness and other brain-associated disorders, and ultimately, it often leaves physicians treating symptoms rather than causes of conditions such as Alzheimer’s and Parkinson’s disease, schizophrenia, attention deficit hyperactivity disorder (ADHD), and many other ailments.

That’s why researchers from two San Antonio institutions have combined forces for the largest study of its kind to map out normal variations in brain structure and function and identify the genes responsible for those variations. They expect their five-year investigation – funded with two new cooperative grants totaling $7 million from the National Institute of Mental Health – to yield a host of new data on basic brain biology and mental illnesses, as well as spawn additional studies focusing on specific diseases.

Why study what’s ‘normal’? Because scientists have not developed a good understanding of basic brain biology and the role of genes, they do not know the root causes of most mental disorders, said geneticist John Blangero, Ph.D., of the Southwest Foundation for Biomedical Research, who is leading the study with David Glahn, Ph.D., psychologist and associate professor at the University of Texas Health Science Center at San Antonio.

To get to the heart of the matter, Blangero and Glahn are taking a different approach from many previous studies of the brain. Rather than looking for research subjects suffering from a particular mental illness and studying differences in their brain structure and function, this research team is working with large family groups from the average population to better understand normal brain variation and the genes that control it.

‘We want to inform aspects of brain biology that are relevant for a lot of different diseases,’ Blangero said. ‘That’s why we’re not focused on any disease. We’re focused on finding the genes that influence normal brain variation. Those are going to be the same genes that also influence pathological variations.’

‘This gives us the potential to evolve some of the basic questions that we’re constantly dealing with from the side of neurologic and psychiatric illness, research areas where it’s difficult to gain traction when you’re focused on the disease itself,’ explained Glahn. ‘This is because the things we’re interested in -- be they cognition, brain structure or brain physiology – are changed dramatically in people with mental illness. So we [in the psychiatric community] are constantly questioning, ‘Is this change [in the brain] a cause of the illness? A result of the illness? A result of treatment of the illness?’ By studying the biology of the brain in healthy subjects, we’ll be able to overcome the ‘chicken-and-egg’ problem that’s constantly there in clinical research.’

Source-Newswise
SRM
'"/>




Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/20/2017)... Petersburg, Fla. (PRWEB) , ... February 20, 2017 , ... ... its research and education building. A topping out ceremony on Friday marked the halfway ... The building, set to open in Fall 2018, will serve as a center for ...
(Date:2/20/2017)... ... February 20, 2017 , ... Today, Illuma Care Connections, ... announced during the 2017 Annual HIMSS Conference & Exhibition in Orlando, ... patients and integrating eye care into mainstream healthcare delivery is powered by ...
(Date:2/19/2017)... ... 19, 2017 , ... The Citadel’s new Swain Department of Nursing , ... Amelia Joseph, Ph.D. Joseph was engaged by the college as a consultant to help ... 2016. After a nation-wide search, she was selected to head the department as nurse ...
(Date:2/19/2017)... ... ... ProBrand Glitch is a set of 30 glitch distortion logo reveals made exclusively for ... with a glitch reveal in just a few clicks of a mouse. Customizable glitch style ... preset. Use these presets to add a uniquely animated logo to any photos or videos. ...
(Date:2/19/2017)... ... February 19, 2017 , ... Orbita, ... will join forces with Healthwise ® at HIMSS 2017 to ... leader in evidence-based health education, technology and services, will demonstrate a voice-powered knowedge ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... February 20, 2017 According to a new market ... Dry powder), Device Type (Metered dose, Dry Powder, Nebulizer)), Canister (Plain, Coated), ... MarketsandMarkets, The market is projected to reach USD 52.37 Billion by 2021 ... the forecast period. Continue Reading ... ...
(Date:2/20/2017)... , February 20, 2017 Acute, Chronic and ... expected to grow at a CAGR of 7% from 2016-2021 and CAGR ... CAGR of 6% from 2016 to 2027. The market is estimated at ... ... Read on to discover how you can exploit the future business opportunities ...
(Date:2/19/2017)... Fla. , Feb. 18, 2017 Nektar ... positive Phase 1 clinical data for Nektar,s lead immuno-oncology ... were presented at ASCO GU 2017.  NKTR-214 is an ... cells and Natural Killer (NK) cell abundance directly in ... these immune cells.  The results were presented by ...
Breaking Medicine Technology: