Navigation Links
Researchers Investigate Gene Linked With Circadian Liver Clock

r2 genes followed the same arc and temporal patterns, suggesting the influence of a shared systemic cue (the authors discovered this was elevated temperature). Since mPer2 transcription can be induced by heat shock and since the mPer2 gene contains binding sites for the transcription factors (HSFs) that activate heat-shock proteins, future experiments will probe whether these transcription factors and binding sites help mediate temperature-dependent mPer2 expression.

By controlling liver clock function with the flip of a molecular switch, the authors showed that only 10% of circadian genes follow temporal expression patterns in the absence of liver oscillators. The authors think these genes probably respond to physical or chemical signals controlled by the master SCN pacemaker. mPer2 is a strong candidate as one of the systemically regulated synchronizers because its expression pattern is almost identical with or without a functional liver clock. A systemically driven mPer2 transcription cycle would provide the necessary link to synchronize the phase of the peripheral oscillator to that of the central system.

Future studies are necessary to illuminate the molecular mechanisms of systemic mPer2 transcription. A number of environmental cues, including elevated temperature and oxidative stress, activate HSF1. It’s possible that HSF1, by sensing rhythmic changes in metabolism, synchronizes peripheral clocks by modulating mPer2 expression. These and similar questions about the signaling pathways that bring all the body’s clocks into the same phase can be explored with the novel transgenic mouse model described here.

Source-Eurekalert'"/>




Page: 1 2 3

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers Investigate Gene Linked With Circadian Liver Clock

(Date:7/3/2015)... (PRWEB) , ... July 03, 2015 , ... ... exclusively to healthcare providers, has been retained to lead a national president ... executive search firms in the healthcare industry, B. E. Smith has recently placed ...
(Date:7/3/2015)... , ... July 03, 2015 , ... ... took place on June 25, 2015 at 1:00pm. The Association welcomed speaker C. ... pertaining to injured bicyclists and practical points of investigating these types of cases. ...
(Date:7/3/2015)... MO (PRWEB) , ... July 03, 2015 , ... Talcum ... website to replace their existing Talcum Powder Cancer Lawsuit Center website. Just as the ... talcum powder lawsuit news , offering timely lawsuit updates and ovarian cancer warning information. ...
(Date:7/3/2015)... ... ... First Choice Emergency Room , the largest network of independent freestanding ... Medical Director of its Frisco facility. , “We are pleased to announce that Dr. ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Manzanares ...
(Date:7/3/2015)... ... 2015 , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh ... reveal biblical truth and expose popular lies regarding proper relationships according to the bible. ... immediately goes into the core of the subject by explaining why certain types of ...
Breaking Medicine News(10 mins):Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 2Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 3Health News:Attorney from William Mattar Leads Discussion on Bicycle Accidents 2Health News:Talcum Powder Lawsuit News: Cancer Attorneys Launch Updated Mobile Site 2Health News:Talcum Powder Lawsuit News: Cancer Attorneys Launch Updated Mobile Site 3Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 2Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 3Health News:Yisrayl Hawkins Explains What the Bible Really Says about Sex in New Publication This Week 2
... Ill., Nov. 12 Pregis Corporation, a leading international ... specialty packaging solutions, today announced its 2009 third quarter ... of 2009, the Company generated net sales of $207.0 ... $265.2 million in the third quarter of 2008. Excluding ...
... protein involved in blood-brain barrier , THURSDAY, Nov. 12 ... on the brain, but it,s too early to say ... researcher reports. , Fredrik Soderqvist, of Orebro University, analyzed ... they had elevated levels of a protein called transthyretin, ...
... eating dark version lowered levels of stress hormones , THURSDAY, ... dark chocolate could cheer you right up by lowering your ... who report their findings in the online issue of the ... said they were highly stressed. , "The study provides strong ...
... ... P.C. has opened its new facility in Lake Success, NY. The facility will ... Epilepsy Neurologist Alan B. Ettinger, M.D., Neuro-Ophthalmologist Scott Uretsky, M.D., Neuropsychologist Gad E. ... children’s facility designed for the needs of pediatric patients. , ...
... Healthcare is an industry faced with unprecedented uncertainty. ... overcome the noise and clearly communicate relevant and timely ... company Griffin York & Krause (GY&K) reaffirmed its commitment ... been honored with six national CardioVascular Advertising (CVA) Awards. ...
... BEACH, Fla., Nov. 12 Commerce Online Inc. (Pink ... company specializing in both bricks and mortar and online ... partnership with RedFin Network, Inc. ( www.redfinnet.com ... Inc. (OTC Bulletin Board: SFNL), to launch its ...
Cached Medicine News:Health News:Pregis Announces Third Quarter 2009 Financial Results 2Health News:Pregis Announces Third Quarter 2009 Financial Results 3Health News:Pregis Announces Third Quarter 2009 Financial Results 4Health News:Pregis Announces Third Quarter 2009 Financial Results 5Health News:Pregis Announces Third Quarter 2009 Financial Results 6Health News:Pregis Announces Third Quarter 2009 Financial Results 7Health News:Pregis Announces Third Quarter 2009 Financial Results 8Health News:Pregis Announces Third Quarter 2009 Financial Results 9Health News:Pregis Announces Third Quarter 2009 Financial Results 10Health News:Pregis Announces Third Quarter 2009 Financial Results 11Health News:Pregis Announces Third Quarter 2009 Financial Results 12Health News:Pregis Announces Third Quarter 2009 Financial Results 13Health News:Pregis Announces Third Quarter 2009 Financial Results 14Health News:Pregis Announces Third Quarter 2009 Financial Results 15Health News:Pregis Announces Third Quarter 2009 Financial Results 16Health News:Wireless Phones Alter Levels of Brain Chemical 2Health News:Neurological Surgery, P.C., of Long Island, NY, Adds New Specialists and Opens New Flagship Facility in Lake Success, NY 2Health News:Neurological Surgery, P.C., of Long Island, NY, Adds New Specialists and Opens New Flagship Facility in Lake Success, NY 3Health News:Healthcare Organizations Face Tough Marketing Challenges - GY&K Asks 'Are You Relevant?' 2Health News:Healthcare Organizations Face Tough Marketing Challenges - GY&K Asks 'Are You Relevant?' 3Health News:Commerce Online Announces Agreement With RedFin Network For Medical Marijuana Dispensary Pre-Paid Loyalty Card Program 2Health News:Commerce Online Announces Agreement With RedFin Network For Medical Marijuana Dispensary Pre-Paid Loyalty Card Program 3
(Date:7/3/2015)... , July 3, 2015 A ... of hypertension, diabetes and thyroid disorders in ... and a major conference dedicated to these diseases. ... Diabetes Online , Manage Hypertension Online and ... operated by EXCEMED - combine the world,s ...
(Date:7/3/2015)... 3, 2015 Redwood Pharma AB ... Co., Ltd., operating in both the US and ... IntelliGel ® supramolecular hydrogel technology in its lead ... ophthalmic therapies. The Broda technology offers many unique competitive ... free-forming liquid and with low concentrations of polymer the ...
(Date:7/2/2015)... 2, 2015 Leading organizations have increasingly ... product and market insights in internal market research ... studies, it is essential for executives to fully ... to capture critical business-related insights. According ... Practices, LLC, most benchmarked companies find it impossible ...
Breaking Medicine Technology:Combating Three Major Chronic Diseases in Latin America With Medical Education 2Redwood Pharma Licenses Novel Hydrogel Drug Delivery Technology From Broda Technologies 2Leveraging Employee Insights to Produce Cutting-Edge Market Research 2
... , ATLANTA ... Bulletin Board: VYST), the creator of Vytex® Natural Rubber ... reduces antigenic proteins found in natural rubber latex, has ... corporate communications firm based in New York City ...
... , , INDIANAPOLIS ... recognized by the eHealthcare Leadership Awards and the Web Marketing ... and wellness tool. , Health Education Answers is a free, ... organizations further drive the quality of patient care through educational ...
Cached Medicine Technology:Vystar Corporation Engages The Investor Relations Group 2Vystar Corporation Engages The Investor Relations Group 3Lilly's Online, Interactive Health Education Program Receives Two Web Awards 2Lilly's Online, Interactive Health Education Program Receives Two Web Awards 3
... performance and value., ,The Aestiva/5 7100 ... the Aestiva/5 anesthesia system (open architecture, integrated ... newest anesthesia ventilation platform - the 7100 ... engineered to allow for ventilation of a ...
... ventilation., ,The Aestiva/5 offers exceptional capabilities ... to anesthesia therapy., ,The Aestiva/5 with ... intensive care ventilator, saving you the cost ... the OR. Its flexible ergonomic design and ...
... An integrated approach to quality patient care., ... an innovative approach to anesthesia delivery. As ... combines enhanced ventilation features, electronically controlled gas ... and information management to create a truly ...
... FlexiGel Strands® Absorbent Wound Dressing is a sterile, ... in moist wound dressing applications. The synthetic ... to the wound contours, and entraps slough and ... debridement. The strands of the matrix are ...
Medicine Products: