Navigation Links
Researchers Identify Gene That Plays Key Role in Size of Dogs -- and Probably in Humans

The results suggest that IGF1 plays a similar role in differentiating small from large dogs within breeds, small from large breeds within dogs, and likely size differences among species.

Cornell's role in the research was in part to show the statistical significance of the pattern of variation found near the IGF1 gene and to demonstrate that selection by humans likely was responsible for the differences in IGF1 between small and large dog breeds using a sample of more than 3,000 dogs from 143 breeds.

"It is staggering to think that so many of the small dog breeds came about through selection on the same mutation in the same gene. These results suggest that while there are invariably differences among breeds (even in genes for size), IGF1 has played an important role in the evolution of many small breeds by being a gene that consistently affects body size," said Bustamante. "The research points to the utility of the domestic dog model system to identify genes that have a large effect."

Because small dog breeds are only distantly related to each other, the researchers believe the gene variation for small dogs probably first appeared early in the history of dogs. As a result of selective breeding of dogs by humans over many generations, dogs today exhibit the greatest diversity in body size of any mammal.

The study's lead author was Nathan Sutter and senior author Elaine A. Ostrander, both of the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health. The study included close collaboration between NHGRI, Cornell, University of Southern California, University of Utah in Salt Lake City, University of California-Los Angeles, University of Missouri in Columbia, the Waltham Centre for Pet Nutrition in Leicestershire, England, and the Nestle Research Center in St. Louis.

Source-Bio-Bio Technology/M
'"/>




Page: 1 2

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
(Date:10/30/2014)... Chicago, IL (PRWEB) October 30, 2014 Dr. ... launched a new website for his practices; OB GYN ... Chicago, IL . This website contains important information about ... covers as well as downloadable patient forms in English and ... use and the service pages on the website provide Dr. ...
(Date:10/30/2014)... Newport Beach, California (PRWEB) October 30, 2014 ... superfood nutrtion bars are now available through a unique ... an online site designed to empower the everyday athlete. ... the worlds best athletes and created a system to ... really excited to see REV’D® is now available on ...
(Date:10/30/2014)... October 30, 2014 Sound Telecom, a leader ... that will assist people any time they wonder, “Should I ... right answer by leading them through a series of yes ... their initial query. , There are many considerations and scenarios ... use an answering service . This decision infographic serves ...
(Date:10/30/2014)... Dennis Thompson HealthDay Reporter ... milk could be bad for your health, a new study ... milk can help strengthen bones and prevent osteoporosis. These benefits ... milk as part of a healthy diet. But this ... not protect men or women from bone fractures, and was ...
(Date:10/30/2014)... Oct. 29, 2014 (HealthDay News) -- A new vaccine ... meningococcal disease was approved by the U.S. Food and ... protect people between the ages of 10 and 25 ... serogroup B bacteria. The bacteria can infect ... spinal cord and brain. It is a leading cause ...
Breaking Medicine News(10 mins):Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2Health News:Nutrition Experts at TheFeed.com Get REV'D 2Health News:Nutrition Experts at TheFeed.com Get REV'D 3Health News:Sound Telecom Produces Decision Infographic to Aid Businesses 2Health News:Is Milk Your Friend or Foe? 2Health News:Is Milk Your Friend or Foe? 3Health News:FDA Approves New Vaccine to Protect Against Meningitis 2
... - Month-12 Independent Echocardiographic Data Safety Monitoring ... Safety Profile -, SAN DIEGO, March ... ) announced today that following a planned ... Board (EDSMB) it is,continuing BLOOM (Behavioral modification ...
... now cover Monogram,s Trofile assay, SOUTH SAN ... MGRM ) today announced that the,California Medicaid ... Trofile Assay., Medi-Cal is the state medical ... care and services to individuals,or families on public ...
... supported by the National Institutes of Health (NIH) ... Infectious Diseases (NIAID) has identified chemical compounds that ... parasitic disease that afflicts more than 200 million ... the advance online publication of the journal Nature ...
... can contribute to weight gain, experts say, , , SUNDAY, March ... for some people be as simple as getting some extra ... don,t get enough sleep tend to weigh more -- and ... and ghrelin. , "There is a dynamic balance between ...
... Guidelines Emphasize Importance of Allergy Testing to Control Chronic ... ... 14 Allergy and asthma specialists,from around the country will gather ... (NAEPP) Guidelines for,the Diagnosis and Management of Asthma. These guidelines are ...
... As the state,s leading health,groups working to reduce the ... continued efforts to enforce the Freedom to Breathe,Act by ... by the City of Maplewood are a positive step,toward ... congratulate,their efforts to protect health," said Pat McKone, Director ...
Cached Medicine News:Health News:Arena Pharmaceuticals' Lorcaserin for Obesity Passes Major Safety Milestone 2Health News:Arena Pharmaceuticals' Lorcaserin for Obesity Passes Major Safety Milestone 3Health News:Arena Pharmaceuticals' Lorcaserin for Obesity Passes Major Safety Milestone 4Health News:Arena Pharmaceuticals' Lorcaserin for Obesity Passes Major Safety Milestone 5Health News:Arena Pharmaceuticals' Lorcaserin for Obesity Passes Major Safety Milestone 6Health News:California Medicaid Establishes Coverage for Trofile(TM) 2Health News:California Medicaid Establishes Coverage for Trofile(TM) 3Health News:California Medicaid Establishes Coverage for Trofile(TM) 4Health News:Scientists identify new leads for treating parasitic worm disease 2Health News:Scientists identify new leads for treating parasitic worm disease 3Health News:Starved for Sleep? Watch Your Waistline 2Health News:Starved for Sleep? Watch Your Waistline 3Health News:NIH Asthma Guidelines Will Leave Sufferers Breathing Easier This Spring 2Health News:Leading Health Groups Applaud Continued Efforts to Protect Public Health by Ending So-Called 'Theatrical Productions' in Bars 2
(Date:10/30/2014)... , Oct. 30, 2014  CytRx Corporation (NASDAQ: ... development company specializing in oncology, today announced an ... lead drug candidate, aldoxorubicin.  The presentation, titled, "Drug ... will be given by Sant P. Chawla ... Center and principal investigator of the Company,s ongoing ...
(Date:10/30/2014)... Extensiv hydrolysierte Milch ... Kuhmilchverträglichkeit     Kuhmilchproteinallergie (KMPA) ist die ... Kleinkindern. Der bisher übliche Umgang mit dieser ... bzw. deren stillenden Mütter Milchproteine zu vermeiden. ... einer beträchtlichen Anzahl von Kindern der Aufbau ...
(Date:10/30/2014)... October 30, 2014 , Extensively ... cow milk   Cow milk protein allergy (CMPA) is the ... childhood. Until now, it has been managed by eliminating ... been shown that it is possible to help build ... number of children during the first year of life ...
Breaking Medicine Technology:CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 2CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 3CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 4Experten präsentieren neuste Forschungsergebnisse auf dem Allergy Day 2Experten präsentieren neuste Forschungsergebnisse auf dem Allergy Day 3Experts Present Latest Research at Allergy Day 2Experts Present Latest Research at Allergy Day 3
... 2011 Aethlon Medical, Inc. (OTCBB: ... to address infectious disease and cancer, announces that ... a company overview, discuss recent developments and review ... & Medical Technologies Virtual Conference.   ...
... June 7, 2011 CMR Institute , the leading ... announces the addition of two new e-modules to help representatives ... (ACA): The Affordable Care ... Accountable Care Organizations and Future Healthcare Delivery ...
Cached Medicine Technology:Aethlon Medical to Discuss Recent Progress at the LHA Life Sciences & Medical Technologies Virtual Conference on June 16 2Aethlon Medical to Discuss Recent Progress at the LHA Life Sciences & Medical Technologies Virtual Conference on June 16 3CMR Institute Adds e-Modules Addressing Healthcare Reform's Impact on Pharmaceutical Industry 2
... EBV laboratory diagnosis is generally confirmed by a ... the disease however, is not indicated by the ... in 10 - 20 percent of children. ... necessary to fully ascertain the stage of EBV ...
... Bard® Biopsy Instrument and Needle is specially ... goal: a large quality, reliable core sample. ... featuring ultra-sharp tips and polished surfaces for ... of biopsy systems and needle sizes assures ...
... to bring efficiency and quality to routine ... superior technology of fluorescent flow cytometry with ... sampling or batch processing are easily accommodated ... in high volume laboratories. Fluorescent flow ...
... The IsoSleeve™ Source Delivery System incorporates ... design that provides the confidence that each ... prior to implant. Unlike other preloaded needle ... verification of the loading configuration giving you ...
Medicine Products: