( For the one in 18 men and women who wil...)Researchers Identify Cell Pathway in Colon Cancer,Health

For the one in 18 men and women who will be diagnosed with cancer of the colon and rectum during their lifetime and over 150,000 people// diagnosed on a yearly basis, today’s genetic research news offers some optimism.

In a study to be published in the Proceedings of the National Academy of Sciences, led by Zhenghe John Wang, Ph.D., Assistant Professor, Department of Genetics at Case Western Reserve University School of Medicine and Case Comprehensive Cancer Center, researchers have identified a cell pathway which plays a critical role in the development of colon cancer. This pathway may also play a role in the development of lung and stomach cancers.

Investigators say they have identified STAT3 {signal transducer and activator of transcription 3}, as a target regulated by PTPRT {Receptor Protein tyrosine phosphatase T}, which was previously identified to be mutated in colon, lung and stomach cancer patients.

"The role of protein tyrosine phosphatase in cancer is still an under-explored area. Our study shows that receptor protein tyrosine phosphatase T regulates an important signaling pathway that is critical in cancer development. This identification will allow new approaches to pharmacological designs and facilitate alternative approaches for cancer treatment”, said Wang.

With over 52,000 deaths each year, colon and rectal cancer is the second leading cause of cancer death in the United States. Colon and rectal cancers begin in the digestive system and may start in a variety of different areas of the GI tract which take years to progress. Both colon and rectal cancer have many commonalities and for that are commonly referred as ‘colorectal cancer’. Most cancers begin as polyps—a growth of tissue into the center of the colon or rectum and when typed as “adenoma”, can become cancerous. The mortality rates have been declining, this in part due to earlier screenings, awareness of symptoms, removing polyps and improve
'"/>




Page: 1 2
Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria