Navigation Links
Researchers Have Linked Rett Syndrome to Mitochondrial Gene

Researchers from the laboratory of Adrian Bird, a molecular geneticist at the University of Edinburgh, Scotland, had announced on 23rd June// that the abnormally high levels of a protein called Uqcrc1 in the brains of mouse used as models of Rett Syndrome is causing its mitochondria, which are the powerhouses of the cells to work overtime. Dr. Bird stated that this is the first time that mitochondrial gene has been linked to Rett Syndrome. The co-author of the study Skirmantas Kriaucionis, who is now attached with the Rockefeller University in New York City, hopes that these finding will lead to treatments for the disorder. He said, “Knowledge of specific physiological defects will, in the future, provide targets for therapeutic intervention”. The research, appears in the July issue of the journal Molecular and Cellular Biology, is being funded partly by the Rett Syndrome Research Foundation.

Rett Syndrome (RTT), a devastating neurological disorder, strikes 1 in 10,000 young children, almost all of them girls. In fact, RTT is the leading genetic cause of severe impairment in girls. Symptoms include neuromuscular problems, autonomic dysregulation, seizures and seizure-like episodes, stereotypical hand movements and the inability to speak. Many children are wheelchair-bound, scoliosis is common, and though the majority live to adulthood, they require total care for every aspect of life.

RTT, which is an autism-spectrum disorder, is caused by mutations in a gene called MECP2. Previous research has shown that the protein made by MECP2 is a master controller of other genes, turning them on and off, and scientists have been searching for these genes. Several have been identified, the best known being brain-derived neurotrophic factor, or BDNF, which normally promotes neuronal growth. To find other genes that MECP2 controls, Bird, Kriaucionis, and other colleagues turned to male mice in which MECP2 has been “knocked out”, meaning they lack the prote
'"/>




Page: 1 2 3

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers Have Linked Rett Syndrome Mitochondrial Gene

(Date:12/24/2014)... HealthDay Reporter TUESDAY, Dec. 23, 2014 (HealthDay News) -- ... year will be allowed to donate blood in the United States, ... on donations from men who have sex with men. The ... a new draft guidance in early 2015 that would ultimately open ... is changing its policy based on data from other countries that ...
(Date:12/24/2014)... (HealthDay News) -- Adults who experienced childhood abuse ... headaches, suggests a study published online Dec. 24 ... maltreatment can have long-lasting effects, like associated medical ... author Dawn Buse, director of behavioral medicine at ... in a journal news release. "When managing ...
(Date:12/24/2014)... Steven Reinberg HealthDay ... New guidelines from the American Diabetes Association (ADA) call for ... with diabetes to help prevent heart disease. These new ... of Cardiology and American Heart Association, which also recommend giving ... heart disease, including people with diabetes. "We agree that ...
(Date:12/24/2014)... MA (PRWEB) December 24, 2014 Dr. ... Dentists from across the nation gathered with US Marines ... Dinner to raise funds for the Toys for Tots ... hundreds of thousands of new books and audio books ... go to underprivileged children this Christmas. It represents another ...
(Date:12/24/2014)... 24, 2014 Verde Pointe Dental Associates 2014 ... "Last years homemade Christmas sweater lit up, but this ... 2014 winner is Tandy Wilson for the second year in ... says Kirk Kimmerling DDS. "She took pictures of the entire ... sweater." , "Every year I enjoy stopping by ...
Breaking Medicine News(10 mins):Health News:FDA to Lift Ban on Blood Donations by Gay Men 2Health News:FDA to Lift Ban on Blood Donations by Gay Men 3Health News:Abuse in Childhood Tied to Migraines in Adulthood 2Health News:Nearly All Diabetics Should Be on Cholesterol-Lowering Drugs: Experts 2Health News:Nearly All Diabetics Should Be on Cholesterol-Lowering Drugs: Experts 3Health News:Dr. Svetlana Gomer, MGS Tewksbury Dental and Other Dentists Working With the U.S. Marines Strike Again In the Battle Against Illiteracy 2Health News:Dr. Svetlana Gomer, MGS Tewksbury Dental and Other Dentists Working With the U.S. Marines Strike Again In the Battle Against Illiteracy 3Health News:Verde Pointe Dental Associates Announces the 2014 Ugly Sweater Holiday Contest Winner 2
... developing a kind of lab-on-a-chip which is a miniaturized, ... astronauts on long missions, who will need the ability ... allergies, anemia or deficiencies in the immune system. ... Space Biomedical Research Institute (NSBRI). ,Along with the ...
... and was later recommendation for all children 2 to 23 months ... pneumonia among young infants. //Studies suggest that the drop in ... due to immunization rather than the vaccine. ,This is ... showed a reduce in the infection rate. But in the present ...
... on the site of Birmingham's Queen Elizabeth Hospital is given a ... the West Midlands have already been announced//. It is funded by ... University Hospitals Birmingham NHS Trust said the trust's finances had been ... , The Treasury has also approved the scheme and said that ...
... watchdog warned the public about the poisonous nature of the apricot ... if consumed in larger quantities could be fatal. ... in death. A maximum of two bitter apricot kernels may be ... the seeds from shop shelves after it was found selling packs ...
... Although the International Monetary Fund on Tuesday gave an ... the dark clouds on the horizon// included worries about ... ,A global avian flu outbreak in humans could cause ... clearing, settlements, trading and communications, the IMF warned in ...
... is a foregone conclusion with no open choices. But does this ... a dignified// and peaceful death? The department of health recently ... of life care to the elderly. ,To research into ... in the sunset of their lives, often die a lonely death. ...
Cached Medicine News:Health News:Technology at its nano best: hand-held lab-on-a-chip for blood tests 2Health News:IMF considers Bird Flu to be a Dark Cloud 2
(Date:12/24/2014)... , Dec. 23, 2014  Lockton Dunning Benefits, ... Lockton Companies, announced the addition of Vice President ... join Lockton Dunning,s Pharmacy Consulting team, Excelsior Solutions. ... relevant industry experience to the position.  Most recently, ... Sales at Diplomat Specialty Pharmacy, where she has ...
(Date:12/24/2014)...  Medical Science Liaisons play a large role in ... medical device industry and key stakeholders, the role of ... as the device industry relies on them to build ... benchmarking firm, Best Practices, LLC, one area where Medical ... by harnessing new technology to enable education. Online conferences ...
(Date:12/22/2014)... MEMPHIS, Tenn. , Dec. 22, 2014   ... only automated, no-touch UV disinfection robot, announced today that ... GSA Schedule contract through November 2019.   ... to rapidly engage all levels of government purchasers, including ... facilities, as well as Homeland Security contacts purchasing solutions ...
Breaking Medicine Technology:Kim Foerster Joins Lockton Companies 2Role of Medical Science Liaisons Evolving in Medical Device Sector 2TRU-D SmartUVC LLC Awarded General Services Administration Contract to Expand Government Customer Base 2
... The Thompson Group of Companies announced today that ... a Hamilton Sundstrand Corporation business. AIT will be organized ... terms of the purchase were not disclosed. ... marketing of process analytical instruments including Analect FTIR, PIONIR ...
... Healthcare Diagnostics announces two new three-year agreements with Novation ... chemistry and microscopy systems, and for microbiology systems and ... VHA and University HealthSystem Consortium (UHC) member organizations and ... The members served by Novation have access to ...
Cached Medicine Technology:Thompson Group Acquires Hamilton Sundstrand's Applied Instrument Technologies 2Novation® Awards Siemens as Single Source for Urine Chemistry and Microbiology Systems and Tests 2
Cleveland Bone Cutter #5, 17cm, 6-3/4"...
Beuse Zygomatic Arch Awl with slightly curved tip....
Steroid-eluting, single-pass lead. CapSure VDD2 optimizes VDD therapy and offers easier handling, proven performance, and choice....
Steroid eluting pacemaker leads...
Medicine Products: