Navigation Links
Researchers Find Two Biomarkers With Potential to Predict Breast Cancer Spread

Expression of two different proteins taken from primary tumor biopsies is highly associated with spread of breast cancer to nearby lymph nodes, according to researchers who// say this protein profile could help identify at an early stage those patients whose disease is likely to metastasize.

In the December 15 issue of Cancer Research, the researchers say over-expression of one unidentified protein and under-expression of another is 88 percent accurate in identifying breast cancer that has spread in a group of 65 patients, compared to an analysis of lymph nodes and outcomes.

If the predictive and diagnostic power of these proteins is validated, they could be analyzed in primary tumor biopsies that are routinely collected at the time of diagnosis, saving some women from extensive and possibly unnecessary treatment as well as from undergoing a second surgery to collect lymph nodes for analysis, the researchers say.

“We want to be able to predict, at the earliest stages, if a tumor has spread and how dangerous it will be,” said the study’s lead author, Dave S. B. Hoon, Ph.D., director of Molecular Oncology at the John Wayne Cancer Institute, Saint Johns Health Center, in Santa Monica, California. “These two proteins may allow us to target aggressive tumors with more extensive therapy management to some women, while sparing others from needless treatment.”

“Our approach is not to rely on hunting for lymph nodes during surgery, which will then only tell you whether the nodes are positive or negative, but to look at the primary tumor to predict how aggressive the cancer is at early stages,” Hoon said.

The lymph system collects the fluid that surrounds tissue cells, which is then processed by nearby draining lymph nodes, so checking these nodes for the presence of cancer is currently one of the most important prognostic factors predicting breast cancer survival, he said. “One of the best predictors of systemic ca
'"/>




Page: 1 2 3 4

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
(Date:9/22/2014)... Steven Reinberg HealthDay Reporter ... that bacterial pneumonia can raise your risk of heart problems, ... and kill heart cells, increasing the chances of heart failure, ... report. In mice, monkeys and human heart tissue, researchers ... and they tried a vaccine that might one day prevent ...
(Date:9/22/2014)... (PRWEB) September 22, 2014 At ... the nonprofit Seafood Nutrition Partnership (SNP) announced the ... Heart Healthy: A Cardiovascular Risk Reduction Program for ... women understand and mitigate their risk of heart ... to Action, a plan for addressing significant global ...
(Date:9/22/2014)... Burbank, CA (PRWEB) September 22, 2014 ... social and mobile recruiting, announced today an ... talent management solutions for the healthcare industry. ... to TweetMyJobs’ suite of social recruiting solutions ... management software designed specifically for healthcare organizations. ...
(Date:9/22/2014)... MAINE AND BOSTON -- In a collaboration that ... advance cancer research and patient care and accelerate ... Beth Israel Deaconess Medical Center (BIDMC) have established ... institutions, presidents announced today. , A recently signed ... Center to establish a comprehensive relationship in the ...
(Date:9/22/2014)... NCPDP, the not-for-profit pharmacy standards development ... 2014 Educational Summit , “Improving the Infrastructure for ... 11, 2014 at the Hyatt Regency Indianapolis. Steven ... Technology, Office of the National Coordinator for Health ... takes place right before NCPDP’s Work Group Meetings, ...
Breaking Medicine News(10 mins):Health News:Scientists Spot How Bacterial Pneumonia Damages the Heart 2Health News:Scientists Spot How Bacterial Pneumonia Damages the Heart 3Health News:At 2014 Clinton Global Initiative Annual Meeting, Seafood Nutrition Partnership Announces Pilot Program to Reduce Women’s Heart Disease Risks 2Health News:At 2014 Clinton Global Initiative Annual Meeting, Seafood Nutrition Partnership Announces Pilot Program to Reduce Women’s Heart Disease Risks 3Health News:At 2014 Clinton Global Initiative Annual Meeting, Seafood Nutrition Partnership Announces Pilot Program to Reduce Women’s Heart Disease Risks 4Health News:TweetMyJobs and HealthcareSource Partner To Provide Social Recruiting Solutions to Healthcare Organizations 2Health News:TweetMyJobs and HealthcareSource Partner To Provide Social Recruiting Solutions to Healthcare Organizations 3Health News:TweetMyJobs and HealthcareSource Partner To Provide Social Recruiting Solutions to Healthcare Organizations 4Health News:The Jackson Laboratory and BIDMC announce multifaceted affiliation 2Health News:The Jackson Laboratory and BIDMC announce multifaceted affiliation 3Health News:NCPDP Educational Summit, Improving the Infrastructure for Continuity of Care, Features Keynote, Steven Posnack 2Health News:NCPDP Educational Summit, Improving the Infrastructure for Continuity of Care, Features Keynote, Steven Posnack 3
... Mary Bono Mack (CA-45) and Nita Lowey (NY-18) ... and well-being of American youth by reintroducing the ... The bipartisan legislation, broadly supported by such organizations ... cross-sector collaboration for improving the health of young ...
... (Nasdaq: MDTH ), (the "Company") a healthcare ... and treatment of cardiovascular disease, today announced that it has ... quarter ended March 31, 2009 and the filing of its ... as a result of an ongoing internal assessment by the ...
... nation,s leading cardioelectrophysiologists, has joined The Mount Sinai Medical Center as ... ... (Vocus)-- Vivek Y. Reddy, M.D., one of the nation,s leading cardioelectrophysiologists, ... of Electrophysiology Laboratories. His appointment becomes effective July 1., , ...
... C. Kolars, M.D., has been named the University ... for Education and Global Initiatives, effective June 1, pending the ... the Medical School,s lead for the oversight and expansion of ... James O. Woolliscroft , M.D., the medical school,s ...
... Fund now has within its reach the potential to ... meeting in Geneva, the Board of Directors of the ... Fund), today agreed to enhance the Fund,s response to ... prevent mother-to-child transmission of HIV (PMTCT), thereby opening the ...
... of the Clopidogrel Medco Outcomes Study presented today during SCAI,s ... may be reduced when taken concurrently with commonly used heartburn ... patients taking clopidogrel and a PPI experienced a: , ... 50% increase in the combined risk of hospitalization for heart ...
Cached Medicine News:Health News:Bono Mack, Lowey Introduce Bill To Improve the Health of Youth 2Health News:Vivek Y. Reddy, M.D., Joins The Mount Sinai Medical Center as Director of Electrophysiology Laboratories 2Health News:Vivek Y. Reddy, M.D., Joins The Mount Sinai Medical Center as Director of Electrophysiology Laboratories 3Health News:Joseph C. Kolars, M.D., to be U-M Medical School's First Senior Associate Dean for Education and Global Initiatives 2Health News:GAA Applauds Global Fund's Decision to Accelerate Support for Treatment Strategies to Prevent Mother-to-Child Transmission of HIV 2Health News:SCAI Statement on 'A National Study of the Effect of Individual Proton Pump Inhibitors on Cardiovascular Outcomes in Patients Treated with Clopidogrel Following Coronary Stenting: The Clopidogrel Medco Outcomes Study' 2
(Date:9/19/2014)... 2014 Medical science liaisons (MSLs) play ... opinion leaders (KOLs) who can provide essential insights ... nature of the MSL function, the changing regulatory ... landscape for creating and maintaining KOL and physician ... oversight responsibility for the MSL function is increasingly ...
(Date:9/19/2014)... "Copay coupons," a drug manufacturer ... drugs among patients with prescription drug coverage, may now be ... report  from the Department of Health and ... anti-kickback laws prohibit suppliers from offering side-payments to ... the federal government. The report ...
(Date:9/19/2014)... 2014 /PRNewswire-iReach/ -- "United States General ... key market data on the United ... report provides value, in millions of ... within market categories – Bronchoscopes, Laryngoscopes, ... Gastroscopes, Duodenoscopes, Laparoscopes, Hysteroscopes, Sinuscopes, Resectoscopes, ...
Breaking Medicine Technology:Role of Medical Science Liaisons Shifting in Healthcare Industry 2PCMA: New OIG Report Cites Drug Manufacturer "Copay Coupon" Use in Medicare Part D 2United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 2United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 3United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 4United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 5
... 2012  Verenium Corporation (Nasdaq: VRNM ), a leading ... high-performance enzymes, today announced that Janet Roemer, Executive Vice President ... Bank Clean Tech, Utilities and Power Conference as part of ... 2:15 p.m. ET on Monday, May 14, 2012 in New ...
... Products, Inc. (NASDAQ: CBPO, "China Biologic" or the "Company"), one ... of China, today announced that it will host its earnings ... 9, 2012 at 8:00 a.m. EDT (New York), which is ... Hosting the call will be Mr. Colin Zhao, President ...
Cached Medicine Technology:Verenium To Present At The Deutsche Bank 2012 Clean Tech, Utilities & Power Conference 2China Biologic Products to Host Earnings Conference Call on May 9, 2012 at 8:00 a.m. EDT (NY) 2
... to 17 parameters from just 95 ... blood gases, as well as any ... metabolite parameters. Unique technology reduces to ... substances have on the accuracy of ...
... a sophisticated whole blood analysis system that ... also satisfying the stringent requirements of the ... contains all of the components of a ... the sampling unit, all of the sensors ...
... The Rapidlab 800 System is a ... key critical care whole blood parameters in ... modular design allows the basic blood gas ... to include electrolytes, metabolites and CO-oximetry in ...
This compact, easy-to-operate analyzer delivers basic blood gas, ISEs with direct measured total hemoglobin and saturated oxygen. Use it as a cost effective backup for the central lab or for remote p...
Medicine Products: