Navigation Links
Researchers Find That Thromboembolism Can Be Safely Treated At Home

Researchers have stated to find in their study that blood clots can be effectively managed at the homes of the patients.//

According to a study that was led by Clive Kearon, professor of medicine at McMaster University that has been published in the August 23 issue of JAMA, The Journal of the American Medical Association the treatment of blood clots in the deep veins of the legs or the lungs with an older and less expensive form of an anticoagulant heparin might be as safe as and effective as the newer and more expensive heparin.

When injected subcutaneously (beneath the skin), unfractionated (regular) heparin was shown in a randomised trial to work just as well as subcutaneous injection of the more expensive, low-molecular weight heparin in the treatment of venous thromboembolism. Traditionally, when unfractionated heparin is used in treatment, it is administered intravenously and accompanied by coagulation monitoring, which requires hospitalisation. This standard approach includes ongoing dose adjustment in response to measurement of the APTT, a test that measures how fast the blood clots in a test tube under certain conditions.

The newer low-molecular weight heparins, which are administered by injection in fixed-weight doses, have gradually been replacing unfractionated heparin.

Kearon and colleagues conducted a randomised trial to study how fixed-dose, subcutaneous injection of unfractionated heparin compared to injection with the newer heparin in the treatment of blood clots in the legs or lungs.

The study was conducted from September 1998 through February 2004 at six university-affiliated clinical centres in Canada and New Zealand. Patients in the trial received either unfractionated or low-molecular-weight heparin administered subcutaneously every 12 hours. About 70 per cent of both groups were treated as outpatients. All patients received three months of warfarin (an anticoagulant drug) therapy. < br>
Recurrent thromboembolism occurred in 3.8 per cent of the 345 patients in the unfractionated heparin group, and in 3.4 percent of the 352 patients in the low-molecular weight heparin group. The rate of major bleeding was comparable in the two groups.

The authors estimate that drug costs for a six-day course of treatment with low-molecular-weight heparin would be $712 (US), while unfractionated heparin would cost just $37 - assuming both drugs are administered in the regimens used in the study. The study indicates the potential for huge costs savings.

"Fixed-dose subcutaneous unfractionated heparin is as effective and safe as low-molecular-weight heparin for initial treatment of patients with venous thromboembolism and is suitable for treatment at home," concluded Dr. Kearon, who is a physician at Hamilton Health Sciences. "In addition, the results of this study question the value of APTT monitoring in patients who are treated with currently recommended doses of unfractionated heparin."

"We've come a long way from having to spend several weeks in hospital with an intravenous heparin drip to a possible out-patient treatment that is safe, efficient, and less expensive," says Dr. Andreas Wielgosz,spokesperson for the Heart and Stroke Foundation.

Source: EurekAlert.
'"/>




Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... ... 08, 2016 , ... After enjoying record-breaking attendance at its ... its 33rd Annual Issues & Research Conference, March 2-3, 2017, at the ... conference is “Persistent Challenges and New Opportunities: Using Research to Accelerate the Dialogue." ...
(Date:12/8/2016)... ... December 08, 2016 , ... Mirixa Corporation ... adherence, and other pharmacist-delivered patient care services, has announced the promotions of Karen ... to vice president of sales. , Litsinger joined Mirixa in 2008 after ...
(Date:12/8/2016)... ... December 08, 2016 , ... Premier Fitness Camp (PFC) and The Chopra Center ... loss and wellness program, at their world headquarters of Omni La Costa Resort & ... results to anyone seeking weight loss, personal development, a healthy lifestyle, or mental and ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... has been recognized for adherence to the highest standards of trauma, maternity, cancer ... announced the center's president and CEO, Dr. Daniel Messina. , Among the recognitions, ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... Care Act. Dr. Botelho advocates for the mass media launching of story movements ... ongoing opportunities to share their unfortunate experiences; such a movement can generate the ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... Allergy Diagnostics Market: Scope and Methodology ... are used to determine the presence of allergens ... etc. in the samples by determining the presence ... report on global allergy diagnostics market, analyzes the ... report consists of an executive summary that provides ...
(Date:12/8/2016)... Mass. , Dec. 8, 2016   ... that Nationwide Children,s Hospital signed a ... and accelerate the development of new cures. ... organizations representing over 57 million patients globally, biopharmaceutical ... working together to improve protocol design, site selection, ...
(Date:12/8/2016)... True Health Diagnostics today announced a ... and management expertise to hospital systems throughout ... doctors and patients to benefit from state-of-the-art biomarker ... Logo - http://photos.prnewswire.com/prnh/20161208/447162LOGO ... to contain costs, have struggled to keep up ...
Breaking Medicine Technology: