Navigation Links
Researchers Find Predictor of Mortality in Cardiac Patients

Researchers at SUNY Downstate Medical Center in Brooklyn have determined that low levels of a protein in the blood is a predictor// of cardiac death in patients with coronary artery disease.

In a group of men undergoing coronary angiography, low baseline levels of RANTES (Regulated upon Activation, Normal T-cell Expressed, and Secreted), also known as CCL5, were shown to be an independent predictor of cardiac mortality.

RANTES is a chemokine produced by a variety of cell types including blood platelets that has been implicated in atherosclerosis. Chemokines are naturally occuring human proteins that signal white blood cells to move in a specific direction, such as to an infection site.

Erdal Cavusoglu, MD, assistant professor of medicine at SUNY Downstate, and colleagues measured baseline RANTES levels in 389 male patients at a Veterans Affairs medical center. The patients were followed prospectively for the occurrence of cardiac mortality and myocardial infarction (heart attack). Results showed that patients with the lowest level of RANTES had the lowest survival rate, and those with the highest levels had the highest survival rates. This was also true for the diabetic subset of patients in the study.

The authors propose several potential explanations for this somewhat paradoxical observation, including potential upregulation of the RANTES receptor, the CCR5 receptor, which is known for its proatherosclerotic properties. Alternatively, lower levels of RANTES may simply reflect greater deposition of RANTES on atherosclerotic arteries with less circulating levels available for measurement by routine ELISA testing.

Source-Eurekalert
'"/>




Page: 1

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/5/2016)... ... May 05, 2016 , ... ... Business Journalists , led by the Wharton School’s most prominent professors, help ... one-day program at the Wharton School’s San Francisco campus will feature Wharton ...
(Date:5/5/2016)... ... 05, 2016 , ... Derrin Doty Group has unveiled the latest charity campaign ... communities west of Seattle. The insurance provider’s caring team has been so moved by ... due to complications from the flu, that they have decided to extend their original ...
(Date:5/5/2016)... (PRWEB) , ... May 05, 2016 , ... ... commencement of a master charity program created to assist the people of their ... working closely with nonprofit organizations and community leaders. Their hope is to bring ...
(Date:5/5/2016)... ... May 05, 2016 , ... Long Island’s fastest growing comprehensive eye care ... Island eye surgeon, Kathleen Van Valkenburg, MD as part of their ongoing effort to ... medical director and managing partner of North Shore Eye Care. , “We are ...
(Date:5/5/2016)... , ... May 05, 2016 , ... ... Pittsburgh-area schoolchildren has found that more than 40 percent of participating fifth-grade students ... , Director of Allergy and Asthma Clinical Research in the Division of Pulmonary, ...
Breaking Medicine News(10 mins):
(Date:5/5/2016)... , May 5, 2016 ... addition of the  "Europe Systemic Lupus Erythematosus ...  report to their offering.       ... The latest research Europe Systemic Lupus Erythematosus ... provides comprehensive insights into Systemic Lupus Erythematosus ...
(Date:5/4/2016)... an upgrade. There are many medical recorders on the market but none like this. ... HD  offers unparalleled connectivity and functionality.  Ampronix  is a renowned authorized reseller of the ... Photo - http://photos.prnewswire.com/prnh/20160503/363416 ... ... ...
(Date:5/4/2016)... JERUSALEM , May 4, 2016 ... University of Jerusalem announced today that it had ... BioTheryX, Inc. , developer of novel protein degradation ... the development and commercialization of drug candidates representing first-in-class ... the license were not disclosed. The novel ...
Breaking Medicine Technology: