Navigation Links
Researchers Find Predictor of Mortality in Cardiac Patients

Researchers at SUNY Downstate Medical Center in Brooklyn have determined that low levels of a protein in the blood is a predictor// of cardiac death in patients with coronary artery disease.

In a group of men undergoing coronary angiography, low baseline levels of RANTES (Regulated upon Activation, Normal T-cell Expressed, and Secreted), also known as CCL5, were shown to be an independent predictor of cardiac mortality.

RANTES is a chemokine produced by a variety of cell types including blood platelets that has been implicated in atherosclerosis. Chemokines are naturally occuring human proteins that signal white blood cells to move in a specific direction, such as to an infection site.

Erdal Cavusoglu, MD, assistant professor of medicine at SUNY Downstate, and colleagues measured baseline RANTES levels in 389 male patients at a Veterans Affairs medical center. The patients were followed prospectively for the occurrence of cardiac mortality and myocardial infarction (heart attack). Results showed that patients with the lowest level of RANTES had the lowest survival rate, and those with the highest levels had the highest survival rates. This was also true for the diabetic subset of patients in the study.

The authors propose several potential explanations for this somewhat paradoxical observation, including potential upregulation of the RANTES receptor, the CCR5 receptor, which is known for its proatherosclerotic properties. Alternatively, lower levels of RANTES may simply reflect greater deposition of RANTES on atherosclerotic arteries with less circulating levels available for measurement by routine ELISA testing.

Source-Eurekalert
'"/>




Page: 1

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun ... NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is ... is geared towards children of all ages; it is a non-competitive, non-timed event, which ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor Rob Lowe, ... in a new episode of "Success Files," which is an award-winning educational program ... investigates each subject in-depth with passion and integrity. , Sciatica occurs when the ...
(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... advisory services for healthcare compliance program management, will showcase a range of technology ... Association for Assisted Living (NCAL) Convention and Expo to be held October 14–18, ...
(Date:10/12/2017)... ... , ... Planet Fitness, one of the largest and fastest growing franchisors and ... flagship location in Covington, LA at 401 N. U.S. Highway 190, in January of ... Depot in the Holiday Square shopping center. Its location allows it to serve both ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company developing ... of targeted tissues, announced three leadership team developments today:   ... ... ... Veteran medical device executive Josh Stopek ...
(Date:9/18/2017)... Sept. 18, 2017 EpiVax, Inc. ... bioinformatics and immune engineering, today announced a ... A (H7N9) vaccine. ... seasonal influenza and presents a challenge for ... exposure to be effective. Using state-of-the-art bioinformatics and ...
(Date:9/12/2017)... 12, 2017  Consumer reviews on the independent review site ... number one company for hearing aids, ranking it higher than ... ... by Consumers For Hearing Aids ... is an online store that provides high performance, state-of-the-art, German-engineered hearing ...
Breaking Medicine Technology: