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Researchers Developing New Therapy to Re-activate Silenced Genes

discriminate between various forms of histone deacetylase.

Kozikowski said the new findings, performed in collaboration with Dr. Brett Langley at the Burke-Cornell Medical Research Institute in White Plains, N.Y., are significant, and that "other exciting results are on the horizon."

Researchers at the Mayo Clinic have found that other histone deacetylase inhibitors they have designed show promise for pancreatic cancer, while yet another, in work performed at the Walter Reed Army Institute of Research, may be effective against malaria.

"This is a new area of drug discovery for the 22nd century," Kozikowski said.


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