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Researchers Develop Model That Aids in Treating Stroke Patients

, something else might be needed to help the tPA work better, Shaw says.

Shaw says the model of the tPA-hypothermia interaction that his team has developed from the study may be useful in helping researchers predict the efficacy of tPA over a wide range of temperatures.

Knowing the effectiveness of tPA at various temperatures could allow a physician to adjust tPA dosing in a stroke patient if hypothermia is being induced as well, says Shaw.

There are multiple medications and treatments for heart attacks, but not for stroke because stroke therapies are still in their infancy. This study offers another potential option for treatment, he added.

The work is reported in the May 2007 issue of Physics in Medicine and Biology.


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