Navigation Links
Researchers Develop Device For Detecting Atherosclerotic Plaques

Researchers from Cedars-Sinai Medical Center had developed a device that will use light emissions from body tissues to detect the inflammation that is //part of plaque formation in the condition of atherosclerosis.

Now, in a study involving laboratory rabbits, a device that stimulates, collects and measures light emissions from body tissues has been able to detect the presence of inflammatory cells that are associated with critical atherosclerotic plaques in humans – plaques that are vulnerable to rupture. The study is described in the August 2005 issue of the journal Atherosclerosis.

Recent atherosclerosis research has found that the composition of plaque and its “vulnerability” to rupture may be more significant than the degree of arterial blockage as a precursor to heart attack and stroke. The lining (intima) of a normal artery consists of several thin layers of cells and connective tissue. Segments containing stable atherosclerotic plaque become thickened with collagen while sections of vulnerable plaque are infiltrated by macrophages. In humans, the inflammatory process weakens the plaque’s thin, fibrous cap, often leading to rupture of the plaque and blockage of blood vessels.

An experimental time-resolved laser-induced fluorescence spectroscopy (TR-LIFS) device developed by researchers at Cedars-Sinai Medical Center was used to detect the presence of inflammatory cells in the aortas of animals, with results compared to those from pathology studies.

Laser-induced fluorescence spectroscopy is based on the fact that when molecules in cells are stimulated by light, they respond by becoming excited and re-emitting light of varying colors. Just as a prism splits white light into a full spectrum of color, laser light focused on tissues is re-emitted in colors that are determined by the properties of the molecules. When these emissions are collected and analyzed (fluorescence spectroscopy), they provide information about th e molecular and biochemical status of the tissue.

Time resolution adds a greater degree of specificity, measuring not only the wavelength of the emission but the time that molecules remain in the excited state before returning to the ground state. This information is valuable because some emissions overlap on the light spectrum but have different “decay” characteristics.

Source: Newswise

'"/>




Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , which ... evacuation of the facility as part of a disaster drill on October 3rd. , ... and Shelton City Emergency Manager, as well as the Connecticut Long Term Care ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Ellevate Network, ... in business to advocate for action towards gender equality at their inaugural Summit in ... around the globe, and reached a social audience of over 3 million. To watch ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... viewers the lowdown on sciatica in a new episode of "Success Files," which ... current events and innovation and investigates each subject in-depth with passion and integrity. ...
(Date:10/13/2017)... ... 13, 2017 , ... “America On The Brink”: the Christian history of the ... is the creation of published author, William Nowers. Captain Nowers and his wife, ... he spent thirty years in the Navy. Following his career as a naval ...
(Date:10/12/2017)... Orleans, LA (PRWEB) , ... October 12, 2017 , ... ... centers in the U.S., announced today its plans to open a flagship location in ... will occupy the former Rooms To Go store next to Office Depot in the ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... 10, 2017  NDS received FDA 510(k) clearance in May 2017 ... display stand specifically designed for endoscopy environments. An innovative secondary monitor ... clinical solution to support the improvement of patient outcomes, procedural efficiency, ... ... ...
(Date:10/4/2017)... Oct. 4, 2017  According to the Centers for Disease Control and ... October . PhysicianOne Urgent Care is helping communities across Massachusetts ... , by offering no-cost* flu shots through the end of the ... certain health insurance regulations. ... time to get a flu shot is by the end of October, ...
(Date:10/2/2017)... -- Halo Labs announces the European launch of their new low ... MIBio 2017 in Cambridge, U.K on October ... biopharmaceutical samples with unprecedented speed and sensitivity while using far less ... Imaging. ... analysis system ...
Breaking Medicine Technology: