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Researchers Analyzes Risk Between Hodgkin Disease and Heart Attack Mortality



"The risk of death from myocardial infarction after treatment for Hodgkin disease remains high for at least 25 years," the authors write. "The increased risks are related to [radiotherapy above the diaphragm] but may also be related to anthracycline and vincristine treatment."

"Long-term studies that follow lymphoma survivors for many years, such as the one conducted by Swerdlow and colleagues, are needed to help better understand the processes and factors that worsen heart function, especially now that patients in remission are living to older ages when cardiac disease is common," writes John D. Boice Jr., of the International Epidemiology Institute in Rockville, Md. and the Vanderbilt-Ingram Cancer Center, Nashville, Tenn, in an accompanying editorial. "The effects of treatment for Hodgkin lymphoma appear to be lifelong, and cancer survivors should be monitored for late cardiac abnormalities throughout their lives. The goal of keeping these patients alive has been achieved; the next challenge is to continue to reduce the toxicity of curative treatments and to make long-term survival as disease free has possible, breaking as few hearts as possible along the way."

Source-Eurekalert
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