Navigation Links
Researcher Discovers Target Site for Developing Mosquito Pesticides

A Mayo Clinic researcher has discovered a target site within malaria-carrying mosquitoes that could be used to develop pesticides that are toxic to the Anopheles gambiae// mosquito and other mosquito species. It would not affect humans and other mammals. If supported by further studies, the findings could offer a safer and more effective control of mosquito-borne diseases such as malaria.

Yuan-Ping Pang, Ph.D., a chemist and expert in computer-aided molecular design at Mayo Clinic, identified two unique amino acid residues called cysteine (286) and arginine (339). These exist in three mosquito species and the German cockroach.

Dr. Pang’s findings are significant because the residues could potentially be used as a target site for a pesticide that would incapacitate only insects that carry these residues, which do not exist in mammals. The findings appear in the current issue of PLoS ONE, a new, peer-reviewed, open-access journal published by the Public Library of Science.

“These findings suggest that new pesticides can be designed to target only the mosquito enzyme. Such pesticides could be used in small quantities to harm mosquitoes, but not mammals,” Dr. Pang says. “We’ve developed a blueprint for a pesticide that could incapacitate malaria-carrying mosquitoes. We are currently making a prototype of the new pesticide.”

Most pesticides today work by crippling the serine residue, which is another amino acid of the enzyme acetylcholinesterase and is located at the active site of the enzyme. This serine residue is present in both insects and mammals and therefore, any pesticide targeting this amino acid affects both insects and mammals. Acetylcholinesterase is a vital enzyme to both insects and mammals. It breaks down the neurotransmitter acetylcholine, which is a primary neurotransmitter in the brain that is associated with memory and cognition.

Dr. Pang, director of Mayo Clinic’s Computer-Aided Molecular Design Labor
'"/>




Page: 1 2 3

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
(Date:8/27/2015)... CA (PRWEB) , ... August 27, 2015 , ... ... plans to enter the exploding legal marijuana industry with the launch of its ... consumers of legal marijuana to order products from their smart phones and tablets. ...
(Date:8/27/2015)... ... August 27, 2015 , ... About 10 percent of ... the Gulf Coast, killing more than 1,800 people, displacing hundreds of thousands and ... State University study. , While most people don’t develop persistent depression after a ...
(Date:8/27/2015)... ... ... The Naderi Center is proud to announce that its own Dr. ... submental fat. The first and only Food and Drug Administration (FDA) approved treatment ... the only Board Certified surgeon in the D.C., Maryland, Virginia area to offer this ...
(Date:8/27/2015)... Yardley, Penn. (PRWEB) , ... August 27, 2015 ... ... engagement solutions, confirmed today that its Krames Patient Education content is ICD-10 ready ... and is ready for the new ICD-10 code sets, which are more targeted ...
(Date:8/27/2015)... ... August 27, 2015 , ... Zensah®, ... Glushko, professional Tennis player for Israel in the Women’s Tennis Association (WTA). Glushko ... her training and recovery. , With a focus on technology and comfort, Zensah® ...
Breaking Medicine News(10 mins):Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 2Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 3Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 4Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 5Health News:About 10 Percent of Mothers Experienced Depression Two Years After Hurricane Katrina, New Study Shows 2Health News:Noninvasive Double Chin Elimination Now Available in Herndon and Chevy Chase 2Health News:Noninvasive Double Chin Elimination Now Available in Herndon and Chevy Chase 3Health News:StayWell announces all health content is ICD-10 ready 2Health News:StayWell announces all health content is ICD-10 ready 3Health News:Zensah® Compression Announces Partnership with WTA Tennis Professional Athlete, Julia Glushko 2Health News:Zensah® Compression Announces Partnership with WTA Tennis Professional Athlete, Julia Glushko 3
... cell startlingly similar to its human counterpart will likely ... organ tissue in people, two studies reported Wednesday. ... the inner-most layer of week-old rodent embryos, will provide ... diseases and injuries, the researchers said. ,"They ...
... Czech authorities said Wednesday the H5N1 virus, which is potentially lethal ... its recent discovery among wild birds in Germany. ... farm near the village of Norin, just four kilometers (2.5 miles) ... after the virus was detected there. ,The farm in ...
... the world, but the situation remains critical in Egypt and ... a major human threat remains high, the UN health ... countries in Asia, Eastern Europe and the Middle East where ... it was rapidly detected and eliminated or controlled," said Joseph ...
... Saing Ratha lies semi-conscious, her thin body shaking with fever as ... ice under her arms. ,Her 10-year-old bother Saing ... in this spartan rural clinic. ,Both have been struck ... in the first six months of this year as during the ...
... Ever dreamed of being drawn close to a smiling Marilyn ... ,A Japanese firm on Wednesday unveiled a ... of three-dimensional images using a sensor-loaded glove. ,The ... of a screen and has a glove that allows users ...
... authorities and United Nations agencies said Thursday they will immunise ... in history. ,The virulent disease is one ... the lives of 58 children a day, but vaccination coverage ... the largest immunization campaign in the world. I think it ...
Cached Medicine News:Health News:'Missing Link' Stem Cells may Shorten Path to Therapies 2Health News:'Missing Link' Stem Cells may Shorten Path to Therapies 3Health News:Potentially Lethal H5N1 Bird Flu Resurfaces in Europe 2Health News:Bird Flu Risk Still Running High in Egypt, Indonesia, WHO Says 2Health News:Dengue Deaths Sweeping Cambodia Highlight Healthcare Failures 2Health News:Dengue Deaths Sweeping Cambodia Highlight Healthcare Failures 3Health News:Pakistan to Launch World's Biggest Anti-measles Drive 2
(Date:8/26/2015)... PUNE, India , August 27, 2015 ... market research reports reviewing the genotyping technology, ... as well as single nucleotide polymorphism (SNP) ... ReportsnReports.com. Complete report on genotyping ... spread across 200 pages, profiling 10 major ...
(Date:8/26/2015)... NEW YORK , Aug. 26, 2015 ... estimated to witness a CAGR of 7.8% during the ... North American ophthalmology cataract surgery devices market in 2014 ... North American ophthalmology cataract surgery devices market is expected ... owing to the increasing strategic expansion of the companies ...
(Date:8/26/2015)... 2015 Edwards Lifesciences Corporation (NYSE: EW ... valves and hemodynamic monitoring, today announced that it has ... privately held company and developer of a transcatheter mitral ... had signed an agreement to acquire CardiAQ. ... $350 million cash for CardiAQ at closing, with an ...
Breaking Medicine Technology:Genotyping Market Forecast to Grow at 22.3% CAGR to 2020 2Genotyping Market Forecast to Grow at 22.3% CAGR to 2020 3Genotyping Market Forecast to Grow at 22.3% CAGR to 2020 4Genotyping Market Forecast to Grow at 22.3% CAGR to 2020 5North America Ophthalmology Cataract Surgery Devices Market by Sub-Market, by End-User - Analysis and Forecast to 2019 2North America Ophthalmology Cataract Surgery Devices Market by Sub-Market, by End-User - Analysis and Forecast to 2019 3Edwards Lifesciences Corporation Completes Acquisition Of CardiAQ 2
Enhances the eye color of light-eyed patients....
Expressions Accents contact lenses let you enhance your eyes natural color while enjoying incredible comfort and outstanding vision quality....
Modern, innovative and quick Intense Pulsed Light system. The Flash 1 is light and very compact, thus easily portable. Available in two different colors....
... Vasculight SR improves the appearance of photo-aged ... benign brown pigments, telangiectasias, and broken capillaries. ... pulsed light (IPLTM) treats pigmentary sun damage ... combined approach of IPL and the Nd:YAG ...
Medicine Products: