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Research on Celiac Disease in children

Oats provided their standard product for the study as there were no GF oats available in the market. 14 children, aged 8 to 16, with normal growth and no abnormalities, consumed oats 25 days per month. They were given 1 gram (gm) of oats for each kilogram (kg) of body weight per day, up to a maximum of 50 gm/day. The clinic followed up by telephone at 1, 3, 6, and 9 months and with blood testing and biopsy at one year. None of the children displayed any symptoms during the year. After one year, one child had elevated blood readings but a normal biopsy. Also, after one year, one child who displayed blunted villi was determined to have been consuming other grains. When the child returned to oats only, the blood antibodies returned to normal in 3 months.

The conclusions that were drawn by Dr. Butzner from his research were:

1. Commercially available oats are OK for celiac children to consume daily for one year.
2. IGA-EMA testing is a sensitive method of monitoring dietary compliance.
3. The quality of antibody testing must be improved so as to be equivalent anywhere.
4. More food testing is needed and standards have to be established.
5. A safe source of oats should be available. To date there have been no failures in two adult CD studies, two adult dermatitis herpetiformis studies and now two children CD studies with oats.


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TAG: Research Celiac Disease children