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Research on Bipolar Disorder Launched

Bipolar disorder is a mental disorder known to have a genetic predisposition. //This study is lead by James Watson, who was a codiscoverer of DNA double helix.

Collaborated Research is being launched by Researchers fom The Zucker Hillside Hospital campus of The Feinstein Institute for Medical Research and Cold Spring Harbor Laboratory to find out the underpinings of bipolar disorder.

"For complex illnesses like bipolar disorder that vary dramatically in symptoms and severity among affected individuals, especially children and adolescents, identifying genetic underpinnings is very difficult," said Anil Malhotra, MD, lead investigator for The Feinstein. "It is also critical to accelerating and confirming a bipolar diagnosis and developing more rational and effective treatments. Collaborating with Cold Spring Harbor Laboratory will help make this a reality."

The collaboration will allow the team to leverage the unique clinical populations at Zucker Hillside, a renowned psychiatric hospital in Glen Oaks, NY, with state-of-the-art molecular tools available at CSHL in Cold Spring Harbor, NY, and The Feinstein Institute in Manhasset, NY.

Commonly referred to as manic depression, BPD is a mood disorder that goes beyond the day's ordinary ups and downs, becoming a serious medical condition and an important health concern in the United States. More than 2.3 million American adults are diagnosed with bipolar disorder, and research suggests that at least a quarter of a million children and adolescents are also affected by bipolar spectrum disorders, though some estimates are much higher. The disorder is characterized by periodic episodes of extreme elation, elevated mood or irritability (also called mania) countered by periodic depressive episodes.

"This collaboration brings together the major elements necessary to understand a complex illness such as BPD," said Dr. Watson. "The clinical and scientific expertise of the phy
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