Navigation Links
Research in the Origin of Microtubules

Researchers at Vanderbilt University Medical Center reveal a surprising new origin for cellular "highways .They report that the Golgi apparatus -- a stack of pancake-shaped compartments that sorts and ships proteins out to their cellular destinations -- is the source of a particular subset of these microscopic fibers.

Scientists have long thought that microtubules, part of the microscopic scaffolding that the cell uses to move things around in order to hold its shape and divide, originated from a tiny structure near the nucleus, called the centrosome.

The findings point to a novel cellular mechanism that may guide cell movement and possibly cancer cell invasion. Microtubules are the largest of the three main types of filaments that make up the cytoskeleton -- a web of microscopic fibers inside the cell.

Microtubules are the largest of the three main types of filaments that make up the cytoskeleton -- a web of microscopic fibers inside the cell.

They form when two globular proteins, alpha- and beta-tubulin, polymerize into long chains, which then assemble into long, hollow tubes. In order to gain a foothold, nascent microtubule "seeds" must be anchored at a structure near the cell's nucleus called the centrosome or microtubule-organizing center (MTOC).

From the MTOC, the growing microtubules launch out in all directions to the cell's periphery. Their rapid assembly and disassembly helps transport proteins throughout the cell and generate polarized (directional) signal distribution that causes cells to move.

While microtubules in some specialized cells can originate from non-centrosomal structures, the centrosome has been considered the main origination point for microtubule "nucleation" in most cells. Until now.

"I've seen that there are lots of microtubules not attached to the centrosome," said Kaverina, assistant professor of Cell and Developmental Biology and senior author on the pap
'"/>




Page: 1 2 3

Related medicine news :

1. Kidney Stones - Interesting New Research implicates bacteria as its cause
2. Researchers urge caution in using ear tube surgery
3. Paracetamol May Cause Live Damage Warns Consumer Education and Research Centre
4. Researchers Scale to assess the Severity of Epilepsy in Kids
5. Research of Ritalin
6. Researchers trick Alzheimers Enzyme
7. Researchers find new HIV hiding place
8. A Compilation of recent Diabetes Research articles
9. Research on causes for falling helps develop preventive strategies
10. New standards for Human Research Safety
11. Research on Celiac Disease in children
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Research the Origin Microtubules

(Date:9/14/2014)... UWDress.com, is an internationally well-known designer and ... its new range of cocktail dresses under $100 ... to worldwide ladies, the company is also providing big ... blue evening gowns, black formal gowns and so on. ... , The company’s senior spokesman says, “We are ...
(Date:9/13/2014)... 13, 2014 Ticket Down is ... tickets. This beloved pop-rock group that originally formed in 1994 ... album. Fans of the group had been anticipating a new ... fans were excited yet about the release of their new ... has announced a massive worldwide tour beginning in the United ...
(Date:9/13/2014)... Termlifeinsurancequotesonline.org has released a new ... for smokers. , Smokers can now find affordable ... examination. The only application process clients have to go ... few medical questions. , Since smoking will increase ... making a decision. Comparing life insurance policies is now ...
(Date:9/13/2014)... September 13, 2014 Bedros Keuilian, founder of ... fitness marketing coach , has always been an advocate of ... most useful days are over, but the post explains that ... need to change. , “A lot of people think of ... says Keuilian. “They run a special and the only thing ...
(Date:9/13/2014)... (PRWEB) September 13, 2014 Gainesville ... the community to their official Grand Opening celebration today, ... part of the international Fit Body Boot Camp franchise, ... workouts designed to get busy people the fast results ... , “Our workouts are hard work, but we make ...
Breaking Medicine News(10 mins):Health News:UWDress.com: Elegant Cocktail Dresses Under $100 Now Offered 2Health News:Maroon 5 Tickets Now on Sale in Philadelphia, Washington DC, Nashville, San Jose, Chicago, Dallas, Los Angeles, Tacoma, Saint Paul, Vancouver, San Diego & New York 2Health News:Maroon 5 Tickets Now on Sale in Philadelphia, Washington DC, Nashville, San Jose, Chicago, Dallas, Los Angeles, Tacoma, Saint Paul, Vancouver, San Diego & New York 3Health News:Smokers Can Qualify for Life Insurance Without Taking a Medical Exam 2Health News:Renegade Fitness Marketing Expert Reveals How Personal Trainers Can Use Groupon More Effectively to Sign New Clients 2Health News:Renegade Fitness Marketing Expert Reveals How Personal Trainers Can Use Groupon More Effectively to Sign New Clients 3Health News:Gainesville Fit Body Boot Camp Announces Grand Opening of New Fitness Boot Camp 2Health News:Gainesville Fit Body Boot Camp Announces Grand Opening of New Fitness Boot Camp 3
... Reporter , THURSDAY, June 23 (HealthDay News) -- After suffering ... hopes and fears about the future are less depressed and ... In fact, 48 percent of the people who participated ... stroke were not depressed a year later, compared to 37.7 ...
... stress appears to enhance the lung-damaging effects of traffic-related ... the Keck School of Medicine of the University of ... will appear online ahead of the print edition of ... and Critical Care Medicine . "This is the ...
... team led by Johns Hopkins researchers has found that a ... with abnormally dense blood vessel growth in the skin lining ... of Familial Cancer , could lead to a quick ... DNA tests and colonoscopies, and sometimes goes unnoticed until cancer ...
... News) -- Among heart attack patients, black Americans generally ... restore blood flow to their hearts, according to a ... hospital quality, not the race of individual patients, the ... attack patients who arrive at hospitals that aren,t equipped ...
... media use, encouraging infants and young children in preschool ... active play, and requiring child care providers to promote ... to curb high rates of obesity among America,s youngest ... Medicine. The report recommends steps that ...
... the Georgia Tech Research Institute (GTRI) have developed a ... disease and certain other neurological conditions to use the ... tremors and relay the results to medical personnel. ... replace subjective tests now used to assess the severity ...
Cached Medicine News:Health News:Early Talk Therapy May Help Stroke Patients Bounce Back 2Health News:Early Talk Therapy May Help Stroke Patients Bounce Back 3Health News:Exposure to parental stress increases pollution-related lung damage in children 2Health News:Hereditary colon cancer syndrome marked by abnormally dense blood vessel growth in mouth 2Health News:Hereditary colon cancer syndrome marked by abnormally dense blood vessel growth in mouth 3Health News:Hospital Delays Tied to Racial Divide in Heart Attack Care 2Health News:Policies that promote healthy eating, activity and sleep are needed to curb obesity in infants, toddlers and preschoolers 2Health News:Policies that promote healthy eating, activity and sleep are needed to curb obesity in infants, toddlers and preschoolers 3Health News:Policies that promote healthy eating, activity and sleep are needed to curb obesity in infants, toddlers and preschoolers 4Health News:New application for iPhone may support monitoring and research on Parkinson's disease 2Health News:New application for iPhone may support monitoring and research on Parkinson's disease 3
(Date:9/12/2014)... DUBLIN , Sept. 12, 2014 ... the "Latin America Home Healthcare (Diagnostics and Monitoring ... Medical Supplies) Market - Trends and Forecast to 2020" ... healthcare devices and services help the patients to be ... by the patient population owing to its cost effective ...
(Date:9/12/2014)... , Sept. 12, 2014   Quest Diagnostics ... provider of diagnostic information services, today celebrates a decade ... and 11 consecutive years on the World DJSI. ... companies for corporate sustainability according to economic, environmental and ... index, companies must continually intensify their sustainability initiatives. ...
(Date:9/12/2014)... REDWOOD CITY, Calif. , Sept. 12, 2014 /PRNewswire/ ... announced that PharmacoEconomics published positive results from ... Oncotype® DX colon cancer test may result in a ... quality of life by helping them avoid side effects ... information which has not been available with conventional measures, ...
Breaking Medicine Technology:Latin America Home Healthcare (Diagnostics and Monitoring Devices, Therapeutic Home Healthcare Devices, Mobility Assist Devices and Medical Supplies) Market - Trends and Forecast to 2020 2Latin America Home Healthcare (Diagnostics and Monitoring Devices, Therapeutic Home Healthcare Devices, Mobility Assist Devices and Medical Supplies) Market - Trends and Forecast to 2020 3Quest Diagnostics Marks 10 Years on the Dow Jones Sustainability Index 2Genomic Health Announces Publication of Colon Cancer Cost-Effectiveness Study in PharmacoEconomics 2Genomic Health Announces Publication of Colon Cancer Cost-Effectiveness Study in PharmacoEconomics 3Genomic Health Announces Publication of Colon Cancer Cost-Effectiveness Study in PharmacoEconomics 4Genomic Health Announces Publication of Colon Cancer Cost-Effectiveness Study in PharmacoEconomics 5
... Emerson Ecologics, LLC, the leading provider of professional-grade ... announced that the company has relocated its eastern ... to Colonial Heights, Virginia. The new distribution center ... Ecologics headquarters and the Eastern customer contact center ...
... ( www.ecardio.com ) announced today their inclusion on Inc. ... the nation,s fastest-growing private companies. eCardio was recognized for ... in the Health segment this year with a three-year ... the most comprehensive look at the most important segment ...
Cached Medicine Technology:Emerson Ecologics Opens Distribution Center Near Richmond, Virginia, Significantly Increasing Capacity 2Emerson Ecologics Opens Distribution Center Near Richmond, Virginia, Significantly Increasing Capacity 3Inc. Magazine Unveils Its Annual Exclusive List of America's Fastest-Growing Private Companies—the Inc. 500|5000 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: