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Research Throws Light on Adaptation of E.coli to Changing Conditions

c and basic conditions.

After at least 1,000 generations, the researchers exposed the groups to either an acidic or basic environment. The groups exposed to acid or base for the entire period had developed into specialists that is, they displayed significant fitness gains when transitioning into their preferred environment.

In contrast, the groups that evolved in variable pH environments exhibited generalist fitness patterns, with neither group having any significant fitness loss in any of the environments. Interestingly, the researchers also found that there was no significant cost to being a generalist at any tested pH level: "Overall, these comparisons suggest that the jack-of-all-trades may be a master of at least some as well," the researchers write.

"What is interesting here is that the complex patterns of adaptation in the various pH regimes were so different among the groups and revealed the first empirical characterization of the intricacies of evolution in response to variable pH," explain the authors. "Plans for future studies include the extension of this experimental evolution system applied to . . . ways in which E. coli may be evolving fitness to survive within the coastal ecosystem or the human host."


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