Navigation Links
Research Offers Hope to Control Meningococci

Bacterial meningitis is caused by meningococcal infection and the disease spreads like wild fire. In Africa 250,000 people were affected// in a matter of weeks in the late 1990s. Mortality rate in cases without treatment is 85-90 percent and with treatment 10-15 percent. Patients also run a high risk of serious disability after recovery.

The World Health Organization, WHO reports that each year 170,000 people around the world die of this type of meningitis.

Only humans are susceptible to infection from meningococci. In its modeling system Ann-Beth Jonsson’s research team therefore used mice that produce the human receptor that the bacteria bind to. Marking the bacteria to emit light, the scientists used cameras to monitor their activities in the living mice during the course of the disease.

“The bacteria are almost knocked out by the immune defense system, but then they resurge, this time with alterations in the surface protein. What’s more, we discovered that the bacteria aggregate in the thyroid and can impact hormone production during the infection,” says Ann-Beth Jonsson.

The study also shows that bacteria that lack a certain adhesin (the protein that the bacteria cells use to adhere to the receptors) could not attach to mucous linings.

Thanks to the new system the research team has developed, it is now possible to rapidly and effectively monitor the function of various vaccine candidates and new drugs, obviating the numerous costly and time-consuming tests that have been necessary until now. At the same time, the system provides a clear picture of the process of infection.

“With these findings as tools, we can continue to study the course of the disease and test vaccines on living organisms. Moreover we will be able to find new strategies for improving the prognoses for those who are affected by meningococcus disorders,” says Ann-Beth Jonsson.

Source-EurekalertPRI
'"/>




Page: 1

Related medicine news :

1. Kidney Stones - Interesting New Research implicates bacteria as its cause
2. Researchers urge caution in using ear tube surgery
3. Paracetamol May Cause Live Damage Warns Consumer Education and Research Centre
4. Researchers Scale to assess the Severity of Epilepsy in Kids
5. Research of Ritalin
6. Researchers trick Alzheimers Enzyme
7. Researchers find new HIV hiding place
8. A Compilation of recent Diabetes Research articles
9. Research on causes for falling helps develop preventive strategies
10. New standards for Human Research Safety
11. Research on Celiac Disease in children
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Research Offers Hope Control Meningococci

(Date:4/17/2014)... identified new pain relief targets that could be ... researchers at King,s College London made the discovery ... the periphery of the body. , Dr Marzia ... mechanisms underlying pain generation and our findings could ... effects." , One potential side effect of some ...
(Date:4/17/2014)... Researchers at the University of California, San Diego School ... those who have suffered a recent major loss are ... older adults. , The study is published in this ... Psychiatry . , Because compassionate behaviors are associated with ... findings offer insights into ways to improve the outcomes ...
(Date:4/17/2014)... University synthetic biology team has created a new ... therapeutics that could travel the body and selectively ... Engineering cell-based, biological devices that monitor and modify ... synthetic biology. However, no existing technology enabled bioengineers ... physiological state and respond in a customized fashion. ...
(Date:4/17/2014)... 2014) The cause of neuronal death in Parkinson,s ... that neurons may be mistaken for foreign invaders and ... the way autoimmune diseases like type I diabetes, celiac ... study was published April 16, 2014, in Nature ... controversial, idea in Parkinson,s disease; but if true, it ...
(Date:4/17/2014)... EcoHealth Alliance, a nonprofit organization that focuses on conservation ... today examining the current state of knowledge of the ... improved global surveillance strategies to combat the emergence of ... in West Africa that has claimed the lives of ... According to the World Health Organization (WHO), the ...
Breaking Medicine News(10 mins):Health News:New pain relief targets discovered 2Health News:The ilk of human kindness 2Health News:Building 'smart' cell-based therapies 2Health News:Is Parkinson's an autoimmune disease? 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 3
... LAUREL, N.J., July 1 MedQuist Inc.,(Pink ... community hospital,located in Westfield, Mass., has selected ... to provide hospital-wide,dictation, transcription and speech recognition ... recognition capability will be,used throughout the hospital ...
... and Bruce Bradley (General,Motors) - to Serve as ... ABIM Foundation,will dedicate its efforts over the next ... and accountability in health care toward the,ultimate goal ... Foundation announced that officers of its Board of,Trustees ...
... WALTHAM, Mass., July 1 Repligen Corporation,(Nasdaq: RGEN ... has been,elected to its Board of Directors. Dr. Goldberg ... School. He is a renowned scientist noted in,particular for ... the mechanism by which most proteins are destroyed in,cells. ...
... fed junk food had higher cholesterol, blood fats into ... News) -- Eating an unhealthy diet during pregnancy may ... cholesterol and blood sugar levels, British researchers report. , ... fed one group of females a diet of processed ...
... Advantages in Efficacy and Safety Will Make Liraglutide the New Clinical ... ... Resources, WALTHAM, Mass., July 1 ... on pharmaceutical and,healthcare issues, finds that a weight neutral oral antidiabetic drug ...
... Health Administrator, Meet Aggressive Hospital Opening Schedule; Eases Ongoing IT ... ... Effort, RIOJA, Spain, July 1 TIBCO Software Inc.,(Nasdaq: ... region of Rioja has deployed its real-time integration,infrastructure. The project at ...
Cached Medicine News:Health News:Award-Winning Massachusetts Hospital Selects MedQuist Enterprise Technology for Clinical Documentation and Speech Recognition 2Health News:Award-Winning Massachusetts Hospital Selects MedQuist Enterprise Technology for Clinical Documentation and Speech Recognition 3Health News:ABIM Foundation Announces New Focus and Governance 2Health News:ABIM Foundation Announces New Focus and Governance 3Health News:Repligen Elects Alfred L. Goldberg, Ph.D. to the Board of Directors 2Health News:Repligen Elects Alfred L. Goldberg, Ph.D. to the Board of Directors 3Health News:Mom's Unhealthy Diet May Have Long-Term Impact on Baby 2Health News:A Weight Neutral Oral Antidiabetic Drug Would Earn a 25 Percent Patient Share in the Type 2 Diabetes Drug Market 2Health News:Rioja Hospital Uses TIBCO Software to Improve Customer Care and Streamline Operations 2
(Date:1/15/2014)... , Jan. 15, 2014 Most osteoporosis patients ... to a recent online survey* sponsored by Mission Pharmacal ... the National Osteoporosis Foundation online support community, revealed that ... medication that comes in a form other than a ...
(Date:1/15/2014)... Jan. 15, 2014  Novation, the leading health care supply ... IT value-added reseller (VAR) national contracts that expand its ... services at lower costs. These include manufacturer product and ... initiative assistance and ongoing IT consulting support. ...
(Date:1/15/2014)... FORT WORTH, Texas , Jan. 15, 2014  Humberto ... in Dermatology Achievement Award" from the Journal of ... Dermatology Aesthetic & Clinical Conference (ODAC). The event is January ... Florida . The ...
Breaking Medicine Technology:Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 2Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 3New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4
... a Conference Call on Monday, April 14, at 8:30 a.m. E.T. ... ... Isis,Pharmaceuticals, Inc. (Nasdaq: ISIS ) announced additional results from its,ongoing ... hypercholesterolemia (FH). In FH patients exposed to,mipomersen for as long as ...
... Researchers from the,Barbara Ann Karmanos Cancer ... adding curcumin or resveratrol to conventional chemotherapy,could ... chemo-resistant colon cancer,cells. The poster presentation was ... (AACR) Annual Meeting in San Diego, CA., ...
Cached Medicine Technology:Update From Mipomersen Extended Dosing Study Continues to Show That Mipomersen Is Well Tolerated and Maintains Activity in Patients Treated for Up to 16 Months 2Update From Mipomersen Extended Dosing Study Continues to Show That Mipomersen Is Well Tolerated and Maintains Activity in Patients Treated for Up to 16 Months 3Update From Mipomersen Extended Dosing Study Continues to Show That Mipomersen Is Well Tolerated and Maintains Activity in Patients Treated for Up to 16 Months 4Update From Mipomersen Extended Dosing Study Continues to Show That Mipomersen Is Well Tolerated and Maintains Activity in Patients Treated for Up to 16 Months 5Update From Mipomersen Extended Dosing Study Continues to Show That Mipomersen Is Well Tolerated and Maintains Activity in Patients Treated for Up to 16 Months 6Karmanos Researchers Find Non-Toxic Agents Added to Conventional Chemotherapy Decrease Survival of Colon Cancer Cells 2
... Supplemental Confirmatory (Western Blot): The assay uses ... on their surface. The cells are fixed ... slide. Fixed, uninfected T-cells are provided as ... sample with HIV- I antibodies comes in ...
Bi-phasic peristaltic infusion pump for tumescent work....
... The Klein Pump provides ... requiring tumescent infiltration. Operates on ... off switch with safety Interlock ... Single Spike Tubing, Double Spike ...
... state of the art Aspirator offers ... It can accommodate up to 5 ... eliminating time consuming canister changes. The ... powerful performance with minimal noise. It ...
Medicine Products: