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Report on the Safety and Effectiveness of Melatonin supplements,,

omnia, which is the the most common sleep disorder, affects 6 -12 % of adults, while 15 - 25 % of children have difficulty initiating or maintaining sleep. Sleep disorders cost an estimated $16 billion in medical costs alone each year. Indirect costs due to lost or sub-standard work productivity, accidents, resulting litigation, and other factors may increase overall costs many fold.

The National Highway Traffic Safety Administration, for example, estimates that 100,000 motor vehicle accidents a year are caused by driver fatigue from sleep deprivation, which is one result of some sleep disorders, and that more than 1,500 people are killed and another 71,000 injured annually as a result.

The evidence report was prepared by a team of researchers led by Terry Klassen, M.D., director of AHRQ's University of Alberta/Capital Evidence-based Practice Centre in Edmonton, and Chair of Pediatrics for the university's Faculty of Medicine and Dentistry. A summary of Melatonin for Treatment of Sleep Disorders can be found at www.ahrq.gov/clinic/epcsums/melatsum.htm . To download the full report as a PDF file, go to www.ahrq.gov/clinic/evrptpdfs.htm#melatonin .

Courtesy NIH Web site at http://nccam.nih.gov

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