Navigation Links
Renewable Oocytes of Mice created hope in Human Fertility Treatment

Using mice as an experimental animal, researchers have discovered that despite its age female mice have a renewable number of oocytes (egg) supply in their ovaries//.

As a preliminary step, this study would pave way for many further discoveries in the field of ovarian stem cell research and women’s fertility treatment – said Professor Jock Findlay from Prince Henry's Institute and Associate Professor Jeff Kerr from Monash's Department of Anatomy and Cell Biology.

The discovery, by Professor Jock Findlay from Prince Henry's Institute and Associate Professor Jeff Kerr from Monash's Department of Anatomy and Cell Biology, has sparked controversy among biologists and challenged the theory, held for more than 50 years, that female mammals are born with a finite number of oocytes (eggs).

Two years ago, international researchers speculated that mice could continue to produce eggs throughout puberty and adulthood. Although their speculation caused debate throughout the scientific community, the scientists could not produce evidence to confirm their idea. However, Professor Findlay and Dr Kerr's research gives support to the theory. Their findings have been published in the July issue of Reproduction.

In the mammalian ovary, reproductive cells called oocytes (eggs) develop within ovarian follicles. In humans, the eggs are believed to die off from late in foetal life, after birth and into adult life. When egg numbers decline towards zero females can no longer reproduce – resulting in the condition we know as menopause.

Professor Findlay, Dr Kerr and their colleagues have found that the total number of eggs in young and normal healthy adult female mice do not decline over time and that overall egg number is maintained for longer than previously thought. Their research suggests that mice have a source of renewable oocytes, Professor Findlay said.

‘The mechanism behind renewable oocytes is still unknown,’ he said. ‘Al though other scientists have suggested that the new eggs come from stem cells in the bone marrow or the ovary, we really don't know and further experimentation is needed to find out.’

Dr Kerr said the phenomenon of egg regeneration in mice did not necessarily mean the same happened in humans. ‘But the mechanism could provide direction for ovarian stem cell research and help women with fertility conditions,’ he said.

One in six Australian couples faces some form of infertility. Due to the limitations and sensitivity of human ovaries, few studies have been conducted into the factors that influence egg survival, growth or death in relation to fertility.

Source: Eurkalert

Related medicine news :

1. Feeding channel created by malaria parasite - a new target for malaria treatments
2. Myth of female impotence created to boost sales
3. Birth mark awareness created by internet helped to treat Cavernous hemangioma
4. Human Genome Project Achieves Technological Triumph
5. First Vaccine Designed for Africa Cleared for Testing in Humans
6. Human gene number increases
7. Scientists found ancient Human Germ Killer
8. New standards for Human Research Safety
9. Human wasting disease linked to a gene
10. The Human Mad Cow Case
11. Human Growth Hormone Found To be Dangerous For Human Use
Post Your Comments:

(Date:6/26/2016)... , ... June 26, 2016 , ... On June 10-11, ... of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, ... the city’s history as home to some of the world’s leading providers of cereal ...
(Date:6/26/2016)... , ... June 26, 2016 , ... PawPaws brand ... new product that was developed to enhance the health of felines. The formula is ... The two main herbs in the PawPaws Cat Kidney Support Supplement Soft ...
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica Scruggs ... for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs surgery, ... Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, MD, ...
(Date:6/25/2016)... Viejo, California (PRWEB) , ... June 25, 2016 , ... ... to fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... fully customizable and all within Final Cut Pro X . Simply select a ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 , , , ... 7, 2016 , , , , LOCATION: , , , ... , , , EXPERT PANELISTS:  , , , Frost & Sullivan,s ... Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program ... global pharmaceutical industry is witnessing an exceptional era. Several new demand ...
(Date:6/23/2016)... Revolutionary technology includes multi-speaker listening ... industry leaders in advanced audiology and hearing aid technology, ... ™, the world,s first internet connected hearing aid that ...      (Photo: ) , ... ,world firsts,: , TwinLink™ - the first ...
(Date:6/23/2016)... Research and Markets has announced the addition ... States, China, Japan, Brazil, United Kingdom, Germany, France, Italy, ... Surgical Procedure Volumes: Global ... surgical procedure volume data in a geographic context. The ... of growth drivers and inhibitors, including world population growth, ...
Breaking Medicine Technology: