Navigation Links
Renewable Oocytes of Mice created hope in Human Fertility Treatment

Using mice as an experimental animal, researchers have discovered that despite its age female mice have a renewable number of oocytes (egg) supply in their ovaries//.

As a preliminary step, this study would pave way for many further discoveries in the field of ovarian stem cell research and women’s fertility treatment – said Professor Jock Findlay from Prince Henry's Institute and Associate Professor Jeff Kerr from Monash's Department of Anatomy and Cell Biology.

The discovery, by Professor Jock Findlay from Prince Henry's Institute and Associate Professor Jeff Kerr from Monash's Department of Anatomy and Cell Biology, has sparked controversy among biologists and challenged the theory, held for more than 50 years, that female mammals are born with a finite number of oocytes (eggs).

Two years ago, international researchers speculated that mice could continue to produce eggs throughout puberty and adulthood. Although their speculation caused debate throughout the scientific community, the scientists could not produce evidence to confirm their idea. However, Professor Findlay and Dr Kerr's research gives support to the theory. Their findings have been published in the July issue of Reproduction.

In the mammalian ovary, reproductive cells called oocytes (eggs) develop within ovarian follicles. In humans, the eggs are believed to die off from late in foetal life, after birth and into adult life. When egg numbers decline towards zero females can no longer reproduce – resulting in the condition we know as menopause.

Professor Findlay, Dr Kerr and their colleagues have found that the total number of eggs in young and normal healthy adult female mice do not decline over time and that overall egg number is maintained for longer than previously thought. Their research suggests that mice have a source of renewable oocytes, Professor Findlay said.

‘The mechanism behind renewable oocytes is still unknown,’ he said. ‘Al though other scientists have suggested that the new eggs come from stem cells in the bone marrow or the ovary, we really don't know and further experimentation is needed to find out.’

Dr Kerr said the phenomenon of egg regeneration in mice did not necessarily mean the same happened in humans. ‘But the mechanism could provide direction for ovarian stem cell research and help women with fertility conditions,’ he said.

One in six Australian couples faces some form of infertility. Due to the limitations and sensitivity of human ovaries, few studies have been conducted into the factors that influence egg survival, growth or death in relation to fertility.

Source: Eurkalert
'"/>




Related medicine news :

1. Feeding channel created by malaria parasite - a new target for malaria treatments
2. Myth of female impotence created to boost sales
3. Birth mark awareness created by internet helped to treat Cavernous hemangioma
4. Human Genome Project Achieves Technological Triumph
5. First Vaccine Designed for Africa Cleared for Testing in Humans
6. Human gene number increases
7. Scientists found ancient Human Germ Killer
8. New standards for Human Research Safety
9. Human wasting disease linked to a gene
10. The Human Mad Cow Case
11. Human Growth Hormone Found To be Dangerous For Human Use
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson Insurance and ... and financial preparation services, is providing an update on a charitable event that ... City Rescue is a locally recognized nonprofit that provides shelter and care for ...
(Date:10/13/2017)... ... 2017 , ... The International Association of Eating Disorders Professionals ... the field of eating disorders, announces the opening of early registration for the ... at the Omni Resort at ChampionsGate. , The annual iaedp™ Symposium ...
(Date:10/13/2017)... Shelton, CT (PRWEB) , ... October 13, 2017 , ... ... and long-term care services, staged a mock evacuation of the facility as part of ... Department, Shelton Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun ... NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is ... is geared towards children of all ages; it is a non-competitive, non-timed event, which ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “The Journey: From ... every danger possible to save lost souls in the Philippines. “The Journey: From the ... is a dedicated teacher of the Bible. She has taught all ages and currently ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... 2017  South Korean-based healthcare product Development Company I.M. ... on Kickstarter. The device will educate the user about ... better efficiency compared to the dated and pricey CPR ... efficacy of the compression for a more informed CPR ... to raise $5,000. ...
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
(Date:10/2/2017)... 2, 2017  Eli Lilly and Company (NYSE: ... the third quarter of 2017 on Tuesday, October 24, ... that day with the investment community and media to ... conference call will begin at 9 a.m. Eastern time. ... live webcast of the conference call through a link ...
Breaking Medicine Technology: