Navigation Links
Relationship Between Serum Dioxin Levels And Age At Menopause

Recent research published in the July issue of the journal Environmental Health Perspectives, demonstrates a non-monotonic dose-response relationship between serum TCDD levels and age of onset of natural menopause//.

The age of onset of menopause is believed to reflect the rate of atrophy of the ovarian follicles. Alterations in age at menopause can have important health implications because women with early menopause are at higher risk for osteoporosis, cardiovascular disease, and reproductive cancers.

2,3,7,8-Tetrachlorobenzo-p-dioxin (TCDD), a halogenated compound that binds the aryl hydrocarbon receptor, is a by-product of numerous industrial processes including waste incineration. Dioxin, a known human carcinogen, is also thought to disturb the reproductive and endocrine systems.

The authors examined the relationship of TCDD and age of onset of natural menopause in a population of women residing near Seveso, Italy, in 1976, at the time of a chemical plant explosion. These women were exposed to the highest levels of TCDD known in residential populations. The study included 616 of the women who participated 20 years later in the Seveso Women?ˉs Health Study (SWHS). All women were pre-menopausal at the time of the explosion, had TCDD levels measured in serum collected soon after the explosion, and were ?Y 35 years of age at interview.

Using proportional hazards modeling, the researchers found a 6% non-significant increase in risk of early menopause with a 10-fold increase in serum TCDD. The results suggest a nonmonotonic dose-related association with increasing risk of earlier menopause up to about 100 ppt TCDD, but not above.

The women in this study experienced substantial TCDD exposure during the post-pubertal¨Cadult developmental period. The authors suggest continued follow-up of the younger women in the SWHS cohort as well as the female offspring of the SWHS cohort.
'"/>




Page: 1

Related medicine news :

1. Relationship bertween birth weight and IQ
2. A Loving Relationship Found To Improve Heart Health
3. Relationship Between Genetic Structure And Quality of Life
4. Understanding The Relationship With Diet And Cataract
5. Romantic Relationships Make People Happy
6. HIV/AIDS Throws Family Relationships Out Of Gear In Uganda
7. Beneficial Symbiotic Relationship Between Ants And Bacteria.
8. Sleeping Position Speaks A Lot About The Couples Relationship
9. Teenage Boys More Vulnerable And Emotionally Engaged In Romantic Relationships
10. Murky Relationships between Doctors and Pharmaceutical Companies Exposed
11. Secure Relationship Leads To Decreased Libido In Women
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/12/2016)... , ... February 12, 2016 , ... The Jones Agency, ... communities across eastern Texas, is launching a cooperative charity drive with the Tarrant Area ... Serving more than 50,000 individuals and families in need, the Tarrant County Food Bank ...
(Date:2/12/2016)... Ramon, CA (PRWEB) , ... February 12, 2016 , ... ... donation in northern California and Nevada, announced a partnership with San Ramon Regional Medical ... transferred to the hospital’s facilities as a way to accommodate a more certain time ...
(Date:2/12/2016)... NY (PRWEB) , ... February 12, 2016 , ... ... of “Revolutionizing Cancer Care.” , The print component of “Revolutionizing Cancer ... Dallas, Pittsburgh/Cleveland, New York, Washington DC/Baltimore, and Seattle, with a circulation of approximately ...
(Date:2/12/2016)... Rafael, CA (PRWEB) , ... February 12, 2016 , ... ... outside Des Moines, Iowa. Legacy Golf Club, located in Norwalk, serves as the host ... of the Year, Rob Randall. , “We have had successful camps in recent years ...
(Date:2/12/2016)... , ... February 12, 2016 , ... ... explosive growth in the field of long term care. With that, says Patrick ... well-trained healthcare professionals in administrative roles in long term care environments. His company, ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... Ontario , Feb. 12, 2016  Aralez Pharmaceuticals ... pharmaceutical company, today announced the Company will ring the Nasdaq ... New York at 4:00 p.m. ... formation of Aralez. Adrian Adams , ... be held 3:50 to 4:00 p.m. ET.  A live ...
(Date:2/12/2016)... February 12, 2016 ... auf den ungedeckten medizinischen Bedarf bei Lungen- ... seines klinischen Forschungsprogramms bekannt. Das Programm, das ... Verbesserungen ihrer respiratorischen Funktionen und anderer klinischer ... ein Medizintechnikunternehmen, das sich auf den ungedeckten ...
(Date:2/11/2016)... 11, 2016 Stem cells are primitive cells ... self-renewal and the capacity to differentiate into mature cell ... as the first mouse embryonic stem cells were derived ... 1995 that the first culturing of embryonic stem cells ... not produced until 2006 As a result of these ...
Breaking Medicine Technology: