Navigation Links
Relationship Between Serum Dioxin Levels And Age At Menopause

Recent research published in the July issue of the journal Environmental Health Perspectives, demonstrates a non-monotonic dose-response relationship between serum TCDD levels and age of onset of natural menopause//.

The age of onset of menopause is believed to reflect the rate of atrophy of the ovarian follicles. Alterations in age at menopause can have important health implications because women with early menopause are at higher risk for osteoporosis, cardiovascular disease, and reproductive cancers.

2,3,7,8-Tetrachlorobenzo-p-dioxin (TCDD), a halogenated compound that binds the aryl hydrocarbon receptor, is a by-product of numerous industrial processes including waste incineration. Dioxin, a known human carcinogen, is also thought to disturb the reproductive and endocrine systems.

The authors examined the relationship of TCDD and age of onset of natural menopause in a population of women residing near Seveso, Italy, in 1976, at the time of a chemical plant explosion. These women were exposed to the highest levels of TCDD known in residential populations. The study included 616 of the women who participated 20 years later in the Seveso Women?ˉs Health Study (SWHS). All women were pre-menopausal at the time of the explosion, had TCDD levels measured in serum collected soon after the explosion, and were ?Y 35 years of age at interview.

Using proportional hazards modeling, the researchers found a 6% non-significant increase in risk of early menopause with a 10-fold increase in serum TCDD. The results suggest a nonmonotonic dose-related association with increasing risk of earlier menopause up to about 100 ppt TCDD, but not above.

The women in this study experienced substantial TCDD exposure during the post-pubertal¨Cadult developmental period. The authors suggest continued follow-up of the younger women in the SWHS cohort as well as the female offspring of the SWHS cohort.
'"/>




Page: 1

Related medicine news :

1. Relationship bertween birth weight and IQ
2. A Loving Relationship Found To Improve Heart Health
3. Relationship Between Genetic Structure And Quality of Life
4. Understanding The Relationship With Diet And Cataract
5. Romantic Relationships Make People Happy
6. HIV/AIDS Throws Family Relationships Out Of Gear In Uganda
7. Beneficial Symbiotic Relationship Between Ants And Bacteria.
8. Sleeping Position Speaks A Lot About The Couples Relationship
9. Teenage Boys More Vulnerable And Emotionally Engaged In Romantic Relationships
10. Murky Relationships between Doctors and Pharmaceutical Companies Exposed
11. Secure Relationship Leads To Decreased Libido In Women
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... October 12, 2017 , ... The ... demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, ... to meet the highest standard. , These products are also: Gluten Free, ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical ... Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. ... honor of Morris F. Collen, a pioneer in the field of medical informatics, this ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... drug delivery system that we intend to develop to enable prevention of a ... lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss ...
(Date:10/12/2017)... , ... October 12, 2017 , ... HMP , ... recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ ... on October 11, 2017. , The annual award competition recognizes editorial and design excellence ...
(Date:10/12/2017)... ... 2017 , ... On Saturday, October 21, the Health & Wellness Center at ... raise money for the American Heart Association Heart Walk. Teams of up to 10 ... to keep their treadmills moving for 5 hours. Treadmills will start at 7:00 p.m. ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)...  True Health, a leader in integrated diagnostics ... National Breast Cancer Awareness month to educate doctors ... Research recently published in ... than 10 million American women are at significant ... BRCA2 and have not had testing. These mutations can ...
(Date:10/5/2017)...  In response to the nationwide opioid epidemic, ... (AAOMS) released prescribing recommendations that urge ibuprofen – ... a first-line therapy to manage a patient,s acute ... Recognizing the value and importance of the ... Acute and Postoperative Pain Management" stresses that practitioners ...
(Date:10/2/2017)... INDIANAPOLIS , Oct. 2, 2017  Eli Lilly ... its financial results for the third quarter of 2017 ... a conference call on that day with the investment ... performance. The conference call will begin at ... public can access a live webcast of the conference ...
Breaking Medicine Technology: