( ely to be alive and free of disease tha...)Regular Exercise Can Help From Recurrence of Colon Cancer,Health

ely to be alive and free of disease than those who were less physically active.

The other study involved 573 participants in the Nurses' Health Study, a project organized by Brigham and Women's Hospital which tracks the health of 121,700 female registered nurses by questionnaires mailed every two years. The nurses included in the current study had undergone surgery intended to cure stage I to III cancer at least six months earlier.

The results of this study mirrored those of the CALGB-based study. Additionally, patients who increased their physical activity from levels before diagnosis had an approximately 50 percent lower chance of dying, from colon cancer or any other cause, than those who remained physically inactive.

"The fact that two different sets of data have yielded such similar results encourages us about the validity of our findings," Meyerhardt remarks. "Although the data from the CALGB study did not include data on the participants' exercise levels prior to diagnosis with colon cancer, we do have that information for those in the nurses study. From that data, it appears that the amount of exercise prior to diagnosis doesn't affect the outcome of treatment. What matters is exercising after standard therapy has been completed."

Scientists do not have a definite physiological explanation for the benefit of exercise for colon cancer survivors, but they speculate it may be tied to a reduction in the body's production of insulin and a similar compound, insulin-like growth factor, which fuel the growth of some cancer cells.

"To reduce the chances that colon cancer will return after treatment, as well as for overall health reasons, regular exercise is a good option for survivors to consider," says Meyerhardt, who also is an assistant professor of medicine at Harvard Medical School. "As with any exercise program, people should check with their doctor before increasing their degree of physical activity."


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