Navigation Links
Reason for diabetes drug causing edema discovered

Researchers had been able to find out why the diabetes drug thiazolidinediones (TZDs) can cause //edema.

Scientists from the University of Utah had found that the drug TZDs activates a receptor in kidney called peroxisome proliferator-activated receptor gamma (PPAR). This is situated in the collecting duct of the kidney. The activation of the receptor serves to retain the fluid in the body and causes edema.

TZD drugs are generally used to lower blood sugar levels and lipid levels and help in controlling blood pressure. However some people can get pulmonary edema and increased risk of chronic heart failure from the drug as side effects.

TZD works by activating PPAR gamma receptor that helps the body to use the insulin to increase metabolism and control blood glucose levels.

The research results showed that in mice the drug caused bloating with increase in body weights. This shows that there is fluid retention in the body that is causing edema. The receptor affects the distal nephron, which plays an important role in deciding the sodium metabolism in the body. Imbalance in sodium retention is one of the causes suspected by the scientists in causing edema.

Reference: Proceedings of the National Academy of Sciences, June 2005
'"/>




Page: 1

Related medicine news :

1. Reasons why men die earlier
2. A Reason To Smile
3. The Reason For Depression in Adolescents
4. Sun The Reason To Blame for eye Disease
5. The Reason For Loss Of Appetite After Gastric Bypass
6. Reasons For Low Back Pain
7. Abnormal Brain Structure One Of The Reasons For Depression in Adolescents
8. The Reason For Depression in Adolescents
9. Testosterone patch for women Rejected For safety Reasons
10. Yet Another Reason To Celebrate Drinking
11. Indian Researcher Discovers Reason For Malignancy of Skin Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... N.J. (PRWEB) , ... October 13, 2017 , ... The ... Holly Day Market. Featuring a collection of specialty vendors and unique items from across ... personalized and quality-focused health and wellness services offered by the VNA. The boutique ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... DevOps and Agile Software Development, has been awarded a contract by the Center ... Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the ... today its plans to open a flagship location in Covington, LA at 401 N. ... To Go store next to Office Depot in the Holiday Square shopping center. Its ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about ... intend to develop to enable prevention of a major side effect of chemotherapy ... especially in pediatric patients. For cisplatin, hearing loss is FDA listed on-label as ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... been named one of Michigan’s 2017 Best and Brightest in Wellness® by Best ... in Wellness® awards program on Friday, Oct. 20 from 7:30 a.m. to 2 ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... AMSTERDAM , Sept. 25, 2017   ... Trial Master File solutions, today—from the IQPC Trial ... Amsterdam , NL)—announced that EastHORN Clinical Services ... its clinical programs and TMF management. EastHORN, a ... Montrium,s eTMF platform to increase transparency to enable ...
(Date:9/22/2017)... -- As the latest Obamacare repeal effort moves is debated, ... and Lindsey Graham (R-SC) medical device market ... is in an odd place.  The industry wants repeal ... on medical device sales passed along with the Affordable ... visits and hospital customers with the funding to invest ...
(Date:9/19/2017)... Sept. 19, 2017   ZirMed Inc ., a recognized ... announced that it has been ranked #1 by its users ... Rankings 2017 User Survey. ZirMed was recognized as the ... hospitals and medical centers over 200 beds and holds one ... technology user survey history. ...
Breaking Medicine Technology: