Navigation Links
Reason for diabetes drug causing edema discovered

Researchers had been able to find out why the diabetes drug thiazolidinediones (TZDs) can cause //edema.

Scientists from the University of Utah had found that the drug TZDs activates a receptor in kidney called peroxisome proliferator-activated receptor gamma (PPAR). This is situated in the collecting duct of the kidney. The activation of the receptor serves to retain the fluid in the body and causes edema.

TZD drugs are generally used to lower blood sugar levels and lipid levels and help in controlling blood pressure. However some people can get pulmonary edema and increased risk of chronic heart failure from the drug as side effects.

TZD works by activating PPAR gamma receptor that helps the body to use the insulin to increase metabolism and control blood glucose levels.

The research results showed that in mice the drug caused bloating with increase in body weights. This shows that there is fluid retention in the body that is causing edema. The receptor affects the distal nephron, which plays an important role in deciding the sodium metabolism in the body. Imbalance in sodium retention is one of the causes suspected by the scientists in causing edema.

Reference: Proceedings of the National Academy of Sciences, June 2005
'"/>




Page: 1

Related medicine news :

1. Reasons why men die earlier
2. A Reason To Smile
3. The Reason For Depression in Adolescents
4. Sun The Reason To Blame for eye Disease
5. The Reason For Loss Of Appetite After Gastric Bypass
6. Reasons For Low Back Pain
7. Abnormal Brain Structure One Of The Reasons For Depression in Adolescents
8. The Reason For Depression in Adolescents
9. Testosterone patch for women Rejected For safety Reasons
10. Yet Another Reason To Celebrate Drinking
11. Indian Researcher Discovers Reason For Malignancy of Skin Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/24/2017)... ... 24, 2017 , ... With ProGlass Prism users now have the ability to ... control over position, rotation, distortion, edge softness, edge blur, chromatic aberration, individual glass position ... With ProGlass Prism users are given the tools and effects to generate a ...
(Date:2/24/2017)... ... February 24, 2017 , ... The Radiology Business ... in radiology marketing programs at the annual Building Better Radiology Marketing Programs ... Worth Hotel in Fort Worth, Texas. Nine awards are given out in five categories. ...
(Date:2/23/2017)... ... February 23, 2017 , ... On February ... a letter to withdraw previous guidance issued by the Obama Administration ... guidance issued in May 2016 by the Obama Administration came in response to ...
(Date:2/23/2017)... ... February 23, 2017 , ... Los Angeles-based weight loss surgeon ... TV’s “Mama June: From Not to Hot,” which will begin airing on February 24, ... known to millions from the 2012 reality television series, “Here Comes Honey Boo Boo.” ...
(Date:2/23/2017)... , ... February 23, 2017 , ... Dr. David Mahon ... Henderson, NV 89052. Dr. Mahon was named a 2017 Top Patient Rated Henderson ... is an online directory that recognizes local physicians and dentists who have earned high ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... , Feb. 23, 2017 Visiomed, ... and services since 1997, is changing the landscape ... technology providing patients with pro-active, custom-made solutions. Recognizing ... for instant and affordable healthcare without walls, Visiomed ... high-level devices developed with healthcare professionals that is ...
(Date:2/23/2017)... -- ITL Limited, ( ASX: ITD ), an innovative diversified healthcare ... ended 31 December 2016 compared with the previous corresponding period. A ... here . Highlights ... Earnings per share of 2.2 cents (Dec 2015: 1.2 ... $15.7m; up 11%) Profit before tax of $2.12m ...
(Date:2/23/2017)... -- Research and Markets has announced the addition of ... report to their offering. ... The latest research Fibromyalgia Drugs Price Analysis and Strategies ... Fibromyalgia market. The research answers the following questions: ... and their clinical attributes? How are they positioned in the Global ...
Breaking Medicine Technology: