( problems with sexual function reported...)Reactions to 'false-positive' Prostate Cancer Screenings Assessed,Health

problems with sexual function reported by men with false-positives could be a residual effect of the biopsy, which can cause short-term pain or other side effects, or it could be an effect from worry about the possibility of still having cancer. "This finding warrants further investigation," he said.

"Men's perceptions following a false-positive prostate screening test are parallel to those of women who have an abnormal mammography exam but whose follow-up biopsy shows no breast cancer," Katz said. "It's understandable that false-positive prostate exams could affect men's outlook on their health."

As with other prostate cancer screening studies, the UI-led study raises the question whether men without any prostate cancer symptoms should receive PSA testing.

Katz said that given the lack of definitive evidence that PSA screening saves lives in asymptomatic men, deciding whether to have a PSA screening test needs to be an individualized decision that considers the patient's current health status and risk factors, such as being African-American and/or having a family history of the disease.

"Men can discuss the pros and cons of getting a PSA test with their doctors. However, once a man decides to go ahead and get a PSA test, if its results are abnormal, he typically should have ongoing follow-up and surveillance for prostate cancer," Katz said.

Katz said that a strength of the UI study was that it did not rely on volunteers. "Volunteers who sign up for a prostate cancer screening study represent a different type of population than that comprised by the individuals in our study, who were patients seen in the usual course of care," he said.

However, Katz noted, a limitation of the study is that the researchers were not able to obtain baseline data on how the men originally felt about their health prior to screening. In addition, the study focused primarily on Caucasian men.

Source-Eurekalert
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