Navigation Links
Re –growing Brain cells destroyed by Parkinson’s disease

Parkinson's disease is a neurodegenerative disease of the substantia nigra ,an area in the basal ganglia. The disease was // first discovered and its symptoms documented in 1817 by the British physician Dr. James Parkinson and the associated biochemical changes in the brain of patients were identified in the 1960s. Although some genes were identified only recently, others still remain a mystery.

In a study done recently it was seen that a drug previously used to relieve the symptoms of Parkinson’s disease , however not available in the market at present due it toxicity fears has now been shown to stimulate growth of the nerve fibres damaged by the disease.

When delivered directly to the brain, glial cell-line derived neurotrophic factor (GDNF) had been shown to stimulate regrowth of cells in animal models of Parkinson’s. However specialists say that it is the first time regrowth has been seen in the human brain.

In a trial study conducted, five patients with advanced Parkinson’s disease were fitted with a tiny catheter that delivered GDNF direct to the putamen, part of the basal ganglia in the centre of the brain. It was observed that some of the symptoms associated with Parkinson’s such as uncontrollable shaking and trembling were reduced in all five patients and they also showed dramatic improvements with respect to their motor skills, verbal memory, facial expressions and motivation.

On studying the brain cells of a patient who died recently and who was part of the GDNF trial researchers say they were able to demonstrate the regrowth of cells in the human brain. Further examination of his brain also revealed that nerve fibres in the putamen had “sprouted” – specifically in the substantia nigra region where the cells that produce dopamine are sited.

Some drug companies manufacturing GDNF have withdrawn the drug from the market after fears over its toxicity despite the fact that the toxicity trials involved testing far higher doses of GDNF on animal models, and that none of the human subjects had showed any ill-effects.

In conclusion researchers say sufferers of Parkinson's disease can now be offered new hope after their recent research has revealed that one can actually be able to regrow brain tissue destroyed by the disease.
'"/>




Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Brain death – How to cope with it
3. “Brain fingerprinting”- The new lie detectr
4. Nasal Spray Could Take Drugs Direct to Brain.
5. Virus Combats Brain Tumour
6. Nasal Spray Could Take Drugs Directly to Brain
7. Control of anger disorder connected to Brain Dysfunction
8. High Levels of Protein Linked to Brain Shrinkage
9. Brain damage affects artistic skill
10. Brain cells protected by new compounds
11. Brain changes observed in people with sleep apnoea
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/25/2017)... , ... July 25, 2017 , ... ... assistance and finance management services to communities across North Carolina, is launching a ... Network to raise community support for the ongoing fight against bladder cancer. , ...
(Date:7/25/2017)... ... ... Facing medical needs with a newborn boy this spring, Crowley Maritime Corp. ... employees that is uncommon in American business: 12 weeks of fully paid parental leave. ... as new parents. It keeps our family life more stable. I can be there ...
(Date:7/24/2017)... ... ... Cheerag D. Upadhyaya , M.D., M.Sc., FAANS has been appointed surgical ... of Saint Luke’s Health System . Dr. Upadhyaya has served in the role ... joins Stanley P. Fisher, M.D., who has served as medical co-director of ...
(Date:7/24/2017)... ... July 24, 2017 , ... A four alarm fire in ... and threatened numerous homes and businesses nearby, causing some 700 individuals to be ... Angeles Area consulting firm Fire Protection Group, Inc. notes that the report is ...
(Date:7/24/2017)... , ... July 24, 2017 , ... ... media initiatives designed to promote awareness for Topricin’s revolutionary, natural, after-burn skin care ... one of the leading causes of long term skin conditions, including cancer. ...
Breaking Medicine News(10 mins):
(Date:7/15/2017)... , July 15, 2017 Enterin Inc., a ... to treat Parkinson,s disease (PD), today announced the completion of ... new investors New Ventures III, as well as the participation ... are absolutely thrilled to have the support of New Ventures ... our investors as validation of the potential of our platform ...
(Date:7/14/2017)... 13, 2017 It should come as no surprise ... is in the midst of a crippling opioid epidemic. According ... the number of overdose deaths from opiate-based medications has quadrupled, ... a million dead from 2001 to 2015". During this time, ... has similarly quadrupled, drawing a compelling link between prescription and ...
(Date:7/13/2017)... Calif. , July 13, 2017 RK Logistics ... Board of Pharmacy certification for its Fremont, CA ... support solutions in the Tri-Valley and San Jose ... City of Fremont , with its Fremont ... Group to provide such a powerful resource to the hundreds ...
Breaking Medicine Technology: