Navigation Links
Radiology advance points way to non-invasive brain cancer treatment

Glioblastoma Multiforme, GBM, is a brain cancer death sentence. It is the most lethal cancer there is.

Of the approximately 12,000 people who are diagnosed with GBM annually in the U.S., half // will die within a year, and the rest within 3 years. The treatments include highly invasive surgeries to remove the tumor and radiation treatment with the maximum tolerated dose, both leading to a very low quality of life. Hence, researchers are racing to find better therapies to stop or slow GBM.

In the January 1, 2006, issue of the journal Clinical Cancer Research, Gelsomina "Pupa" De Stasio, professor of physics at the University of Wisconsin-Madison, and colleagues report on research into use of a new radiotherapy technique to fight GBM with the element gadolinium. The approach might lead to less invasive treatments and that offer greater promise of alleviating the disease.

The therapy, called Gadolinium Synchrotron Stereotactic Radiotherapy (GdSSR), requires a gadolinium compound to find tumor cells and penetrate them, down to their nuclei, while sparing the normal brain. Then, the patient's head is irradiated with X-rays. The whole brain is transparent to X-rays, while gadolinium is opaque. Then, where gadolinium is localized—in the nuclei of the cancer cells only—the “photoelectric effect" takes place.

"Exactly 100 years after Einstein first explained this effect, we have found a way to make it useful in medicine," De Stasio says. "In this effect, atoms absorb photons and emit electrons. The emitted electrons are highly destructive for DNA, but have a very short range of action.

Therefore, gadolinium atoms must be localized in the nuclei of cancer cells to induce DNA damage that the cancer cells cannot repair, and consequently cell death."

De Stasio says it will be a year before it is known whether the treatment works in animal models, and likely another five to ten years before any clinical trials and avai
'"/>




Page: 1 2

Related medicine news :

1. Hospital Selected to ‘25 Most Influential’ List in Radiology in 206
2. Kalam to Commission Indias First Tele-Radiology Network
3. President’s Address on the ‘Tele-Radiology’ Set Up of Krst
4. The negative advancement
5. Innovative device aids in advanced heart failure
6. Light therapy devotes new hope in advanced lung cancer
7. Race an important links to the risk of advanced colorectal cancer
8. New advance in prostate cancer management
9. NICE supports application of advanced biological therapies as treatment option for acute psoriasis
10. Study points out that HIV vaccine may not be accepted easily
11. Multi billion-dollar suit filed against cell phone firm for causing brain tumours
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Radiology advance points way non invasive brain cancer treatment

(Date:7/9/2014)... Perelman School of Medicine at the University of Pennsylvania ... received an $8 million grant from the National Cancer ... therapy (PDT) in patients with malignant pleural mesothelioma, a ... itself in the lining of the lungs and is ... will fund a clinical trial and additional studies looking ...
(Date:7/9/2014)... More scientific research into the metabolism of stromal support ... the metabolism of these cell types in the development ... diabetes, inflammatory conditions and cancer. That was the conclusion ... KU Leuven in the leading journal Nature . ... sort of wake-up call. The metabolism of cancer cells ...
(Date:7/9/2014)... personal and subjective, the human brain turns them ... across different senses, situations and even people, reports ... Anderson. , "We discovered that fine-grained patterns of ... of the brain associated with emotional processing, act ... subjective feeling," says Anderson, associate professor of human ...
(Date:7/9/2014)... for more than watching World Cup highlights, Brian Williams ... landing in unfortunate positions on railings. A University of ... Online Journal shows that YouTube also allows researchers, ... public on topics of skin cancer and prevention. , ... the future of how we communicate around the world," ...
(Date:7/9/2014)... and poor printing on prescription labels handed out ... to errors in taking medication, according to new ... (Canadian National Institute for the Blind)., The study, ... , found that labels on prescription medications dispensed ... guidelines for legibility. , By simply following recommended ...
Breaking Medicine News(10 mins):Health News:Penn mesothelioma program receives $8 million NCI grant 2Health News:Wake-up call for more research into cell metabolism 2Health News:Study cracks how the brain processes emotions 2Health News:Study of dermatology on YouTube shows new ways science reaches public 2Health News:Most prescription labels fail to meet guidelines, risking dosage errors 2
... Hologic, Inc.,(Nasdaq: HOLX ), a leading developer, ... and surgical products dedicated to,serving the healthcare needs ... quarter and fiscal 2008 operating results on Tuesday, ... the release, management will,host a conference call on ...
... Credentialing Center (ANCC) has designated Geisinger Medical Center (GMC) ... conference call to hospital administrators, nurses and staff who ... elite group of only 15 Pennsylvania hospitals and ... achieved Magnet status. More than 6,000 hospitals are eligible ...
... Delaying, avoiding radiation could lessen long-term side effects, study ... Using chemotherapy alone, and delaying or avoiding radiation altogether, ... progressive low-grade glioma brain tumors, according to a multi-institutional ... tumor in children. If surgery can be performed, the ...
... ANN ARBOR, Mich.---The University of Michigan received $5 million ... world,s leading resource of high-quality experimental data sets of ... to a new level. , The resource will ... can predict the effectiveness of potential new drugs, said ...
... CT adds metabolic information from PET to traditional CT ... maximized workflow ... quick return on investment, MUNICH, Germany, Oct. 10 ... new concept in,integrated imaging that provides a premium imaging ...
... ... Front Line, PHILADELPHIA, Oct. 9 ... more than,590 customer service representatives (CSRs), by rewarding them with fun,healthy activities ... 4 million inquiries a year, IBC,s CSRs are more than,just busy -- ...
Cached Medicine News:Health News:Hologic, Inc. To Release Fourth Quarter and Fiscal 2008 Operating Results on Tuesday, November 11, 2008 2Health News:Geisinger Medical Center earns prestigious Magnet designation 2Health News:Chemo Alone Effective in Treating Kids' Brain Tumors 2Health News:U-M to house leading drug database 2Health News:Siemens Shapes the Future of Integrated Diagnostic Imaging 2Health News:Siemens Shapes the Future of Integrated Diagnostic Imaging 3Health News:Siemens Shapes the Future of Integrated Diagnostic Imaging 4Health News:Independence Blue Cross Celebrates Customer Service Week 2
(Date:1/15/2014)... Medical is very pleased to announce the appointment of Mr. ... Officer.  Mark was promoted from his current role of Chief ... facilities in Massachusetts , Mississippi ... in 2012 with 20+ years of broad-based operations, sales, engineering ...
(Date:1/15/2014)... PHILADELPHIA , Jan. 15, 2014  Echo Therapeutics, Inc. ... company developing its Symphony® CGM System as a non-invasive, ... Robert F. Doman , Executive Chairman and Interim CEO ... Capital Markets, Tenth Annual Equity Conference. ...
(Date:1/15/2014)... , Jan. 15, 2014  According to Millennium ... technology market intelligence, the United States ... (TEO) device markets will expand moderately through 2022, ... segments. In particular, increasing interest in drug-eluting beads ...
Breaking Medicine Technology:Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 2US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 3
... , CARTERSVILLE, Ga. ; June 2 ... Women (GASC) – Georgia ,s first fully ... minor gynecological surgeries in a true ... facility specializes in laparoscopic and other highly advanced, ...
... (Nasdaq: FHCO ) announced that it has fulfilled an order for 3.5 million ... World Cup. The 2010 World Cup will take place in The Republic of ... . , , , ... three million tickets to the games, is expected to flood the country with visitors. ...
Cached Medicine Technology:New Georgia Advanced Surgery Center Provides Women Many Unique Benefits 2The Female Health Company Receives Order for 3.5 Million FC2 Female Condoms for Distribution at 2010 World Cup 2The Female Health Company Receives Order for 3.5 Million FC2 Female Condoms for Distribution at 2010 World Cup 3
... dual-monochromator, multi-detection microplate reader with a ... reading capability. Detection modalities include absorbance ... and have optical performance comparable to ... Endpoint, kinetic, spectrum and area-well scanning ...
... of PCR, cDNA and Oligonucleotides The ... for a variety applications that are quantified by ... to handle assays in Microplate formats from ... Cuvettes Independent whether you have ...
... High Throughput Screening (HTS), Analyst HT ... HTS by sharing all the detection ... AD, fluorescence intensity, fluorescence polarization, time-resolved ... seamless integration into robotic environments, including ...
... Designed for Ultra High Throughput ... multimode assay detection performance. Allows for ... from assay development by sharing all ... and HT, fluorescence intensity, fluorescence polarization, ...
Medicine Products: