Navigation Links
Radiology advance points way to non-invasive brain cancer treatment

Glioblastoma Multiforme, GBM, is a brain cancer death sentence. It is the most lethal cancer there is.

Of the approximately 12,000 people who are diagnosed with GBM annually in the U.S., half // will die within a year, and the rest within 3 years. The treatments include highly invasive surgeries to remove the tumor and radiation treatment with the maximum tolerated dose, both leading to a very low quality of life. Hence, researchers are racing to find better therapies to stop or slow GBM.

In the January 1, 2006, issue of the journal Clinical Cancer Research, Gelsomina "Pupa" De Stasio, professor of physics at the University of Wisconsin-Madison, and colleagues report on research into use of a new radiotherapy technique to fight GBM with the element gadolinium. The approach might lead to less invasive treatments and that offer greater promise of alleviating the disease.

The therapy, called Gadolinium Synchrotron Stereotactic Radiotherapy (GdSSR), requires a gadolinium compound to find tumor cells and penetrate them, down to their nuclei, while sparing the normal brain. Then, the patient's head is irradiated with X-rays. The whole brain is transparent to X-rays, while gadolinium is opaque. Then, where gadolinium is localized—in the nuclei of the cancer cells only—the “photoelectric effect" takes place.

"Exactly 100 years after Einstein first explained this effect, we have found a way to make it useful in medicine," De Stasio says. "In this effect, atoms absorb photons and emit electrons. The emitted electrons are highly destructive for DNA, but have a very short range of action.

Therefore, gadolinium atoms must be localized in the nuclei of cancer cells to induce DNA damage that the cancer cells cannot repair, and consequently cell death."

De Stasio says it will be a year before it is known whether the treatment works in animal models, and likely another five to ten years before any clinical trials and avai lable treatments would emerge.


'"/>




Related medicine news :

1. Hospital Selected to ‘25 Most Influential’ List in Radiology in 206
2. Kalam to Commission Indias First Tele-Radiology Network
3. President’s Address on the ‘Tele-Radiology’ Set Up of Krst
4. The negative advancement
5. Innovative device aids in advanced heart failure
6. Light therapy devotes new hope in advanced lung cancer
7. Race an important links to the risk of advanced colorectal cancer
8. New advance in prostate cancer management
9. NICE supports application of advanced biological therapies as treatment option for acute psoriasis
10. Study points out that HIV vaccine may not be accepted easily
11. Multi billion-dollar suit filed against cell phone firm for causing brain tumours
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2016)... ... May 26, 2016 , ... There are many ways to cook ... Council (NHDSC) suggests that Americans prefer their dogs straight off the grill. Of the ... is their favorite way to cook a hot dog, far outpacing other cooking methods ...
(Date:5/26/2016)... Atlanta, Georgia (PRWEB) , ... May 26, 2016 ... ... a certificate in intellectual property (IP) to its specialty academic programs. , Answering ... joins the college’s existing certificate programs in health law, and environmental and land ...
(Date:5/26/2016)... ... May 26, 2016 , ... Cardiac ... significant negative impact on long-term patient survival, reports a team of UPMC researchers ... this week in the Journal of Thoracic and Cardiovascular Surgery, provide critical information ...
(Date:5/26/2016)... , ... May 26, 2016 , ... ... Degeneration” for the Foundation Fighting Blindness, Long Island Chapter on June 4, 2016, ... public. , Dr. Maisel, founder of Retina Group of New York , ...
(Date:5/26/2016)... Indianapolis, Indiana (PRWEB) , ... May 26, 2016 ... ... national provider of healthcare supply chain solutions, today announced the organization has earned ... management meets international standards and is compliant with all rules and policies associated ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... 26, 2016 According to a new ... Market - U.S. Industry Analysis, Size, Share, Growth, Trends, and ... the U.S. was valued at US$ 5.89 Bn in 2014 ... from 2015 to 2023 to reach US$ 7.99 Bn in ... and emerging needle free drug delivery devices and the market ...
(Date:5/25/2016)... FDA 510(k) clearance covers Confocal Miniprobes ... and surgical applications Mauna Kea Technologies ... multidisciplinary confocal laser endomicroscopy (CLE) platform, today announced ... the 12 th 510(k) clearance from United ... FDA clearance covers Confocal Miniprobes indicated for use ...
(Date:5/25/2016)... YORK , May 25, 2016  According to ... reached $381 billion in 2015.  Though these are ... plenty of opportunity for success for companies that ... in search of new growth prospects medical device ... on research and development (R&D) than do companies ...
Breaking Medicine Technology: