Navigation Links
Radiology advance points way to non-invasive brain cancer treatment

Glioblastoma Multiforme, GBM, is a brain cancer death sentence. It is the most lethal cancer there is.

Of the approximately 12,000 people who are diagnosed with GBM annually in the U.S., half // will die within a year, and the rest within 3 years. The treatments include highly invasive surgeries to remove the tumor and radiation treatment with the maximum tolerated dose, both leading to a very low quality of life. Hence, researchers are racing to find better therapies to stop or slow GBM.

In the January 1, 2006, issue of the journal Clinical Cancer Research, Gelsomina "Pupa" De Stasio, professor of physics at the University of Wisconsin-Madison, and colleagues report on research into use of a new radiotherapy technique to fight GBM with the element gadolinium. The approach might lead to less invasive treatments and that offer greater promise of alleviating the disease.

The therapy, called Gadolinium Synchrotron Stereotactic Radiotherapy (GdSSR), requires a gadolinium compound to find tumor cells and penetrate them, down to their nuclei, while sparing the normal brain. Then, the patient's head is irradiated with X-rays. The whole brain is transparent to X-rays, while gadolinium is opaque. Then, where gadolinium is localized—in the nuclei of the cancer cells only—the “photoelectric effect" takes place.

"Exactly 100 years after Einstein first explained this effect, we have found a way to make it useful in medicine," De Stasio says. "In this effect, atoms absorb photons and emit electrons. The emitted electrons are highly destructive for DNA, but have a very short range of action.

Therefore, gadolinium atoms must be localized in the nuclei of cancer cells to induce DNA damage that the cancer cells cannot repair, and consequently cell death."

De Stasio says it will be a year before it is known whether the treatment works in animal models, and likely another five to ten years before any clinical trials and avai lable treatments would emerge.


'"/>




Related medicine news :

1. Hospital Selected to ‘25 Most Influential’ List in Radiology in 206
2. Kalam to Commission Indias First Tele-Radiology Network
3. President’s Address on the ‘Tele-Radiology’ Set Up of Krst
4. The negative advancement
5. Innovative device aids in advanced heart failure
6. Light therapy devotes new hope in advanced lung cancer
7. Race an important links to the risk of advanced colorectal cancer
8. New advance in prostate cancer management
9. NICE supports application of advanced biological therapies as treatment option for acute psoriasis
10. Study points out that HIV vaccine may not be accepted easily
11. Multi billion-dollar suit filed against cell phone firm for causing brain tumours
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/7/2016)... PITTSBURGH, PA (PRWEB) , ... December 07, 2016 , ... ... and regular changing of the securement tape is painful for her. "This is why ... cannula’s to patients’ heads," she said. , They then created a prototype of the ...
(Date:12/7/2016)... ... 2016 , ... A. Kevin Spann Insurance, a New York-based firm offering insurance ... launching a charity drive to raise funds that will benefit the Marine Corps League. ... and Navy FMF Corpsmen. Working closely with the MCL, the A. Kevin Spann team ...
(Date:12/7/2016)... ... 07, 2016 , ... Sharon Kleyne, host of the nationally syndicated radio program, ... Voice of America, declared on her radio program in November 2016 the need to ... these bullies attack leaders in corporate America, they are trying to take advantage of ...
(Date:12/7/2016)... ... December 07, 2016 , ... Facial plastic surgeon, Dr. John D. Rachel ... a portion of proceeds to two local organizations: North Chicago Animal Control and Friends ... is a team of authorized and trained volunteers who support rescued animals held ...
(Date:12/7/2016)... Dallas, TX (PRWEB) , ... December 07, 2016 ... ... service based in Dallas, Texas, is condemning "scam operations" carried out by unethical ... to bring these scam operations to a halt. According to Texas Premier Locksmith, ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... 7, 2016 Global Cervical Dysplasia Market: ... global cervical dysplasia market analyzes the current and ... an elaborate executive summary, including a market snapshot ... sub-segments. The research is a combination of ... bulk of our research efforts along with information ...
(Date:12/7/2016)... , Dec 7, 2016 Research and ... Application and End User - Global Forecast to 2021" report to ... , , ... USD 2.12 Billion by 2021, growing at a CAGR of 7.3% during ... as the growing prevalence of cancer and rapidly increasing geriatric population across ...
(Date:12/7/2016)... 7, 2016  Palatin Technologies, Inc. ("Palatin") (NYSE ... a previously disclosed underwritten public offering of units ... as sole book-running manager, Roth Capital Partners acted ... as co-manager for the offering. "This ... net proceeds, allowing us to continue advancing bremelanotide ...
Breaking Medicine Technology: