Navigation Links
RNA Nanotechnology To Rescue Cancer Patients In Future

Scientists have now developed tiny delivery vehicles that can carry anticancer therapeutic agents directly into infected cells, using strands of genetic material constructed through nanotechnology, offering a potential wealth // of new treatments for chronic diseases. This emerging branch of science is called nanomedicine.

These delivery agents are called nanoparticles, and are assembled from three short pieces of ribonucleic acid. The microscopic particles are designed in such a way that they possess both the right size to gain entry into cells and also the right structure to carry other therapeutic strands of RNA inside with them, where they are able to halt viral growth or cancer's progress.

RNA or ribonucleic acid has immense promise as a therapeutic agent against cancer, and furthermore, it might be possible to deliver multiple therapeutic agents to the cell at the same time, adding versatility and potential to the medical valve of the nanoparticles.

RNA molecules come in many variant forms, and the sort that the team mimicked from the phi29 virus – called pRNA – also can be linked to other types of RNA to form longer, hybrid strands with properties the researchers could assign. The nanoparticles have been created by linking together different kinds of RNA, after the successful manipulation of these stringy molecules into different shapes, including rods, triangles and arrays.

An effective agent against cancer needs to accomplish several tasks. It needs first to recognize the cancer cell and gain access to its interior, and then it needs to destroy it. It is also important for the molecule to act like a tracer that can provide valuable information regarding the location and the outcome of treatment.

Particles pass through cell membranes into the cell's interior, and the body has a hard time retaining particles smaller than 10 nanometers. But the tiny triangles fit, and they worked well enough to interrupt the grow th of human breast cancer cells and leukemia model lymphocytes in laboratory experiments.

"One characteristic of cancer cells is that they do not stop growing, which is one reason tumors develop," said Guo, a senior researcher. "Once inside, the siRNA essentially instructs the cells to 'stop not stopping.' The nanoparticles had done their work on the breast cancer cell cultures within a few days."

"The results are very promising, but we still have several hurdles to jump before we can test this therapy on people," Guo said. "First and foremost, we must ensure that it is as safe as we think it is. Some RNA can be toxic to noncancerous cells as well, and though our nanoparticles appear to go straight to the cancer cells where we want them to go, we have to be sure they do not go anywhere else before we can inject them into a living person.

Nanotechnology is beginning to pay off here in that it may have provided us with a solution to the problem. We hope to enhance the work we have done so far and refine it for human trials."


'"/>




Related medicine news :

1. CoQ10 bioavailability increased by Nanotechnology
2. Nanotechnology Revolution To Be Spearheaded By European Union
3. Scientists Consider About New Technology Called Nanotechnology
4. Potential Benefits Of New Nanotechnology
5. Nanotechnology Promises Huge Medical Benefits
6. Nanotechnology at its best: Nanomotors And Mechanical Nanoswitches
7. Nanotechnology Could Revolutionize Cardiac Treatment
8. Anti-Sense Drugs and Nanotechnology Offer New Hope In Cancer Fight
9. Nanotechnology – to detect and treat ovarian cance
10. Nanotechnology Used For Detecting Viruses
11. India, China Trying to Fight Disease With Nanotechnology
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/10/2016)... ... February 10, 2016 , ... Intermedix ... of Emergency Medicine , an emergency medicine professional association, to support the organization's ... , The American Academy of Emergency Medicine, or AAEM, seeks to empower emergency ...
(Date:2/10/2016)... , ... February 10, 2016 , ... Emergency rooms provide ... to find. Unfortunately, this can leave patients with dental emergencies at risk of losing ... now offering emergency dental care. , Common dental emergencies include:, ...
(Date:2/10/2016)... ... February 10, 2016 , ... Dr. Jessica Barron, of ... is now accepting new dental patients and families in the North Metro Denver area. ... services from cleanings to cosmetic dentistry, and all in the most relaxing environment. , ...
(Date:2/10/2016)... , ... February 10, 2016 , ... ... organization, welcomes S.S. Nesbitt as the latest addition to its growing list of ... other locations throughout the Southeast, from Orlando to Huntsville and in between. , ...
(Date:2/10/2016)... ... , ... Armune BioScience signed a definitive agreement with ARCpoint ... across the country. Launched in April of 2015, Apifiny is the only cancer specific, ... order volume exceeded 3,000 tests in 2015. Primary care physicians and urologists have utilized ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... LONDON , February 10, 2016 A new report ... 2021 - states that the Alzheimer,s disease market will more than double ... 2021, at a Compound Annual Growth Rate (CAGR) of 11%. ... Italy , Spain , the UK, and ... prevalence during the forecast period. --> Canada , ...
(Date:2/10/2016)... SAN DIEGO , Feb. 10, 2016 ... viral gene therapy manufacturing, and Renova™ Therapeutics, a biopharmaceutical ... and other chronic diseases, have entered into a Manufacturing ... produce cGMP-grade RT-100 (Ad5.hAC6) Drug Product for use in ... --> This relationship will leverage Lonza,s ...
(Date:2/10/2016)... , Feb. 10, 2016 Immune Pharmaceuticals Inc. ... announced today that it has filed a patent application ... other cancers. --> --> ... by administration of Ceplene (histamine dihydrochloride) in combination with ... of predicting the efficacy of Ceplene and IL-2 therapy ...
Breaking Medicine Technology: