Navigation Links
RA Drugs Not Implicated In Cancer

Rheumatoid arthritis (RA) patients have an increased risk of developing lymphoma and leukemia. The autoimmune, inflammatory disease that causes a lot of joint pain does have the risk of cancer. //Researchers speculate that antirheumatic drugs (DMARDs) – including tumor necrosis factor alpha (TNFá) antagonists, a type of biologic DMARD may play a role in this.

TNF blockers, which work by attaching to and impeding chemical messengers behind inflammation, have had a significant impact on the treatment of RA. They have also been linked to lymphoma among users. In fact, reports of lymphoma prompted the Food and Drug Administration to mandate adding a cancer risk warning to the labels of three TNF blockers: etanercept (Enbrel), infliximab (Remicade), and adalimumab (Humira).

Motivated by persistent concerns and inconclusive studies, researchers at Harvard Medical School's Brigham and Women's Hospital set out to investigate the association between treatment with TNF blockers and occurrence of cancer in a large sample of patients with RA. Their results, featured in the September 2006 issue of Arthritis & Rheumatism (http://www.interscience.wiley.com/
journal/arthritis), indicate that biologic DMARD therapy poses no greater risk for cancer than therapy with a standard prescription DMARD, methotrexate (MTX).

The researchers focused on 7,830 RA patients, age 65 and older, drawn from healthcare databases in New Jersey, Pennsylvania, and British Columbia, Canada. Subjects included 1,152 biologic DMARD users and 7,306 MTX users. Of those treated with a biologic DMARD, 64 percent had used etanercept, 33 percent had used infliximab, and the remaining 2 percent had used anakinra (Kineret). 55 percent had previously used MTX and 39 percent were receiving MTX when they began anti-TFN therapy.

Based on medical utilization information, the researchers measured every subject's general health and RA-related characteristics during the 6-mo
'"/>




Page: 1 2

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
3. Nasal Spray Could Take Drugs Direct to Brain.
4. Emphasis to ban Drugs ads by Doctors
5. Osteoporosis Drugs: right time to take-off
6. Drugs disrupt formation of blood vessels
7. Drugs to stop burgeon of HIV
8. Misleading Advertisements for Prescription Drugs
9. Drugs For Anthrax May Interfere With Oral Contraceptives
10. Over-The-Counter Drugs May Prevent Alzheimers
11. Steps To Improve Quality Of Plant-Based Drugs
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Drugs Not Implicated Cancer

(Date:7/24/2014)... the body,s own immune system play a role in ... chronic epilepsy, Alzheimer,s dementia and concussions? Cleveland Clinic researchers ... PLOS ONE . , The study focuses on ... serves as a biomarker for brain damage. Normally, S100B ... However, following a brain injury, it can leak through ...
(Date:7/24/2014)... For the first time in her career, ... Scottish singer first became a known musical commodity after appearing on ... on the show was “I Dreamed a Dream,” from Les Misérables ... albums since her time on the reality show in 2009 and ... her American fans. The tour will kick off on October 8 ...
(Date:7/24/2014)... high school students are smoking tobacco products at the ... new data from the Prevention Research Center for Healthy ... more than 22 percent, or one in five high ... the prior 30 days. , Equally surprising is that ... or water pipes, more than cigarettes matching a ...
(Date:7/24/2014)... News) -- Even though its use is often advised by ... does not help treat lower back pain, according to a ... was no more effective than a dummy pill for more ... Besides showing no effect in easing discomfort, the study also ... tied to back pain, nor did it improve patients, overall ...
(Date:7/24/2014)... K. Brenner, MD, PhD, Baylor College of Medicine (Houston, ... research toward understanding how tumors are able to escape ... genetically modified T cells that can effectively target tumors. ... the field, Dr. Brenner is the recipient of a ... peer-reviewed journal from Mary Ann Liebert, Inc., publishers. ...
Breaking Medicine News(10 mins):Health News:Immune response may cause harm in brain injuries, disorders 2Health News:Susan Boyle Tickets: Dazzling Deals Tickets Cuts Ticket Prices for Susan Boyle's 2014 North America Concert Tour 2Health News:Susan Boyle Tickets: Dazzling Deals Tickets Cuts Ticket Prices for Susan Boyle's 2014 North America Concert Tour 3Health News:Susan Boyle Tickets: Dazzling Deals Tickets Cuts Ticket Prices for Susan Boyle's 2014 North America Concert Tour 4Health News:Cuyahoga County high school students smoking at the same rate as adults 2Health News:Cuyahoga County high school students smoking at the same rate as adults 3Health News:Cuyahoga County high school students smoking at the same rate as adults 4Health News:Acetaminophen May Not Help Against Back Pain, Study Contends 2Health News:Acetaminophen May Not Help Against Back Pain, Study Contends 3Health News:Malcolm K. Brenner receives Pioneer Award for advances in gene-modified T cells targeting cancer 2
... a twin are at upto 5 times higher risk of suffering ... was conducted on over 800 pairs of twins in the UK ... age of 40 was 3-5 times higher in twins than women ... ten years or earlier than the usual period. Only 1-in-100 women ...
... The diagnosis of Kylie Minogue with breast cancer has led to ... get breast cancer//. ,Cancer Research UK said that ... strike the under-70s than women over 70,. ,Their survey ... that a woman's risk of breast cancer was increased if she ...
... toddlers, reports a major study conducted on the side effects of ... proposed immunization for all kids of the age 6 months to ... sharp rise in the number of children getting vaccinated. This proposal ... years as often as the old people. ,This study ...
... A 1-year-old girl has been diagnosed with polio in spite ... an official statement, polio can be prevented by 4-10 doses ... this girl called Jannat. ,“Earlier she used to ... Jannat's Mother, Akhbari Khatun says.,Jannat was diagnosed with polio just ...
... from heart surgery. A Researcher from the University of Calary has ... Kathryn King, in her research informs that those who wore ... and discomfort, when compared those who were in a ... to the Canadian Cardiovascular Congress in Vancouver after two years of ...
... A recent research proposes that radiations from handsets may affect fertility ... count than normal.// ,A study conducted on 361 ... the daily mobile use by the man, there was a decrease ... a 40% reduction in sperm count in men who used mobile ...
Cached Medicine News:Health News:Mobile use increases risk of infertility in men 2
(Date:7/24/2014)...  Bruin Biometrics (BBI), a pioneer in biometric-sensor ... weeks of clinical briefings to over 200 pressure ... substantial concurrence on both the clinical validity of ... BBI,s SEM Scanner. "From our ... drawn from the European Wound Management Association (EWMA) ...
(Date:7/24/2014)... July 24, 2014  Bayer HealthCare today announced ... evaluated a 15% foam formulation of its compound ... inflammatory papules and pustules of rosacea. An AzA ... complement the currently available AzA gel formulation. Papulopustular ... (papules and pustules) as well as erythema (redness) ...
(Date:7/24/2014)... , July 24, 2014  Market Diagnostics ... IVD Insights™ LabFile , a data resource ... US clinical laboratory universe and identifying target In ... a proprietary database that provides IVD manufacturers with ... tests, relying on clear and consistent definitions of ...
Breaking Medicine Technology:Bruin Biometrics Secures Support of EU Scientific Community for its SEM Scanner Technology 2Phase III Investigational Trial of Azelaic Acid 15% Foam Meets Both Co-Primary Endpoints in Subjects with Papulopustular Rosacea 2Phase III Investigational Trial of Azelaic Acid 15% Foam Meets Both Co-Primary Endpoints in Subjects with Papulopustular Rosacea 3MDxI Launches Data Resource Setting New Standard for Defining and Targeting US Clinical Laboratory Universe 2
... June 18, 2007 /PRNewswire/ -- Today, results,from ... comparing two angiotensin,receptor blockers (ARBs) in hypertensive ... 17th annual European Meeting on,Hypertension in Milan, ... parallel group,multicenter study included 860 hypertensive patients,(>130/80mmHg) ...
... 2007 --- Millipore Corporation today announced the release ... lines. The,research was conducted by the Department ... plc, whose ReNcell,distribution agreement with Millipore was announced ... Dr. Vi Chu, research &,development scientist for Millipore’s ...
Cached Medicine Technology:New Data Presented on Micardis (Telmisartan) Tablets in,Hypertensive Patients With Type 2 Diabetes 2New Data Presented on Micardis (Telmisartan) Tablets in,Hypertensive Patients With Type 2 Diabetes 3New Data Presented on Micardis (Telmisartan) Tablets in,Hypertensive Patients With Type 2 Diabetes 4Millipore Corporation Announces New ReNcell Data from Collaboration,with ReNeuron 2Millipore Corporation Announces New ReNcell Data from Collaboration,with ReNeuron 3Millipore Corporation Announces New ReNcell Data from Collaboration,with ReNeuron 4
... Design for Unparalleled Comfort Pick one of ... balance. Notice the trigger and ejector positionsright where ... our pipettors are ergonomically designed to help avoid ... pipetting. Productivity In The Palm Of Your ...
... best value in high performance electronic pipetting!, ... lightweight design reduce hand fatigue and strain ... tip ejector , Color coding for easy ... for greater performance use Hamilton AdvanTip Low ...
... The Finnpipette BioControl ... innovative features as the ... universal handle fits all ... single channel tip cone ...
... Entire Column of a 384 Well Plate at ... 384 well plates, you need a pipettor that ... exactly what you get with our 16-channel Impact ... Impact/Impact2), this innovation was specifically designed to allow ...
Medicine Products: