Navigation Links
Quitting Not Easy for Smokers Born to Smoking Women

Smokers born to mothers who smoked during pregnancy may find it difficult to stop smoking according to a recent study//.

A recent animal research suggests that individuals exposed to nicotine while in the womb may find it difficult to quit smoking. Duke University Medical Center researchers conducted this research.

Prenatal exposure to nicotine is known to alter areas of the brain critical to learning, memory and reward. Scientists at the Duke Center for Nicotine and Smoking Cessation Research have discovered that these alterations may program the brain for relapse to nicotine addiction. Rodents exposed to nicotine before birth self-administer more of the drug after periods of abstinence than those that had not been exposed.

The study suggests that pregnant women should quit smoking to avoid exposing their unborn children to nicotine, and that they should do so without the use of nicotine products such as patches or gums that also present a risk to the baby, the researchers said.

"Smoking during pregnancy can harm the baby in ways that extend far beyond preterm delivery or low birth weight," said lead study investigator Edward Levin, Ph.D., a professor of biological psychiatry. "It causes changes in the brain development of the baby that can last a lifetime."

Results of the study appear this week in the online issue of the journal Pharmacology, Biochemistry and Behavior. The National Institute on Drug Abuse and Philip Morris USA supported the work.

Levin's team exposed pregnant rats to nicotine. Once the offspring grew to adolescence, they were allowed to self-administer nicotine as often as they wanted. To self-administer the drug, the rats pressed a lever that caused a dose of nicotine to be delivered intravenously. Each push of the lever was roughly equivalent to a hit from a cigarette.

The researchers studied two groups of rats: those that had been exposed to nicotine prenatally and those that had not. Initially, both groups of rats consumed nicotine at the same rates -- about ten hits per session. After four weeks, the researchers forced the rats to go "cold turkey" for a week, during which they had no access to nicotine.

Once the scientists restored access to nicotine again, they witnessed a dramatic difference in the rates at which the two groups resumed the habit. The rats that had been exposed prenatally took nearly double the nicotine hits compared with those that had not.

While the rates of smoking in the United States are declining, approximately a quarter of Americans have mothers who smoked during pregnancy, Levin said. Previous studies have shown these individuals have a higher chance of sudden infant death syndrome, attention deficit-hyperactivity disorder, obesity and even of becoming a lifelong smoker themselves, Levin said.

"It is easy to quit smoking -- anyone can do it, for a brief time," Levin said. "But not taking it up again -- that is the part that has proven so difficult for most people, especially those who have been exposed to nicotine before birth."

Levin and his colleagues say that different smoking cessation approaches should be taken in individuals who have been exposed to nicotine prenatally. Whether or not a person has been exposed to nicotine while in the womb becomes another part of their medical profile that helps doctors tailor treatment to the specific needs of the patient, Levin said. Some other factors shown to influence a person's ability to quit include gender, age, state of mental health and genetics, he added.

Other researchers participating in the study were Susan Lawrence, Ann Petro, Kofi Horton, Frederic J. Seidler and Theodore A. Slotkin.

Source-Eurekalert
PRI
'"/>




Related medicine news :

1. Quitting smoking stops lung decline
2. Quitting the smoking habit
3. Women Benefit More from Quitting Smoking than Men
4. Quitting Smoking Made Easy By Track Of New Chemical
5. Quitting Psychotherapy Midway May Be Preventable
6. Taylor & Campbell Quitting NHS
7. Taylor & Campbell Quitting NHS
8. Smokers are Prone to Weight Gain After Quitting
9. Save your Vision with Fish Oil and Quitting Smoking
10. Women Smokers Fear Quitting Will Lead to Weight Gain
11. For Smokers Only: is Quitting = Cutting Down?? a grave Issue
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... , ... June 25, 2016 , ... On Friday, June ... a Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments ... of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott ...
(Date:6/24/2016)... Marne, Michigan (PRWEB) , ... June 24, 2016 , ... ... awareness about the dangers associated with chronic pain and the benefits of holistic treatments, ... for individuals who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda ... orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including ... accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB ... Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards ... in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With ...
(Date:6/24/2016)... ... , ... National recruitment firm Slone Partners is pleased to announce ... experience, as Vice President of North American Capital Sales at HTG Molecular . ... sales team in the commercialization of the HTG EdgeSeq system and associated reagents in ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... NAMUR , Belgium , ...  (NYSE MKT: VNRX), today announced the appointment of ... Board of Directors as a Non-Executive Director, effective ... the Company,s Audit, Compensation and Nominations and Governance ... Board, Dr. Futcher will provide independent expertise and ...
(Date:6/23/2016)... 2016 Any dentist who has made an implant ... process. Many of them do not even offer this as ... high laboratory costs involved. And those who ARE able to ... a high cost that the majority of today,s patients would ... Parsa Zadeh , founder of Dental Evolutions Inc. and inventor ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Global MEMS Devices Medical Market Analysis 2016 - Forecast to ... The report contains up to date financial ... reliable analysis. Assessment of major trends with potential impact on ... dive analysis of market segmentation which comprises of sub markets, ...
Breaking Medicine Technology: