Navigation Links
Quality Of Dietary Carbohydrates May Determine Quality Of Eye Sight

In older adults Age-related Macular Degeneration (AMD) is one of the primary causes of vision loss and a person's risk to develop the disease may partly depend upon his diet.// The quality of the carbohydrates consumed must be of primary concern rather than the quantity, according to a research led by Allen Taylor, PhD, director of the Laboratory for Nutrition and Vision Research , at Tufts University. Their findings were published in theApril 2006 issue of the the American Journal of Clinical Nutrition.

Taylor and colleagues analyzed data from a sub-group of participants in the Nurses' Health Study (NHS) who were enrolled in the Nutrition and Vision Program. The researchers looked at the total amount of carbohydrates consumed over 10 years and the dietary glycemic index, which is a measure of the quality of overall dietary carbohydrate.

"Women who consumed diets with a relatively high dietary glycemic index had greater risk of developing signs of early age-related macular degeneration when compared with women who consumed diets with a lower dietary glycemic index," says lead author Chung-Jung Chiu, DDS, PhD, scientist in the Laboratory for Nutrition and Vision Research at the HNRCA and an assistant professor at Tufts University School of Medicine. High total carbohydrate intake, however, did not significantly increase the risk factor for AMD.

"In other words, the types of carbohydrates being consumed were more important than the absolute amount," explains Taylor, senior author. A high-glycemic-index diet is one that is rich in high-glycemic-index foods, which are converted more rapidly to blood sugar in the body than are low-glycemic-index foods.

Chiu, Taylor, and colleagues examined the eyes of more than 500 women between 53 and 73 years of age, looking for changes indicative of early AMD. The researchers also analyzed the participants' diets, as reported in questionnaires that had been administered periodically over the course of 10 years preceding their eye exams.

"Dietary glycemic index may be an independent and modifiable risk factor for early AMD," concludes Taylor, who is also a nutrition, ophthalmology and biochemistry professor on the Tufts health sciences campus in Boston. "The likelihood of having abnormalities characteristic of AMD on eye exam more than doubled for women who consumed diets with the highest glycemic index, regardless of other factors already known or suspected to increase the risk of AMD, such as age, high blood pressure, cigarette smoking, and obesity."

AMD primarily and irreversibly affects central vision, which is critical for many activities, such as reading and driving. The disease is caused by the gradual breakdown of light-sensitive cells in the region of the eye's retina called the macula. It is estimated that 1.75 million Americans 40 years of age and older have some manifestation of AMD.

Prior to the current study, the association between AMD and dietary carbohydrate had not been evaluated. "We are interested in studying the role of glucose in age-related diseases like AMD," Taylor says, "because evidence suggests that problems with glucose metabolism, as in diabetes, may cause damaging by-products to accumulate in sensitive tissues and contribute to disease."

"We cannot say, based on these data, whether or not consuming a diet with a high glycemic index causes AMD," says Taylor. He points out that there are other possible explanations for the relationship he and his colleagues observed. "Perhaps a high-glycemic-index diet is a marker for an overall dietary or lifestyle pattern that increases the risk of developing AMD." A diet high in high-glycemic-index foods like white bread and french fries has a higher overall glycemic index than a diet based more heavily on low-glycemic-index foods, such as lentils and yams.

Taylor is cautious in his interpretation of this data, but he believes that further research is critical, as it may ultimately prove helpful in preventing or delaying the onset of such potentially debilitating and costly diseases.

### Chiu C-J, Hubbard LD, Armstrong J, Rogers G, Jacques PF, Chylack LT, Hankinson SE, Willet WC, Taylor A. American Journal of Clinical Nutrition. 2006 (April); 83(4): 880-886. "Dietary glycemic index and carbohydrate in relation to early age-related macular degeneration."

If you are interested in learning more about this topic, or speaking with a faculty member at the Friedman School of Nutrition Science and Policy at Tufts University, or another Tufts health sciences researcher, please contact Siobhan Gallagher at 617-636-6586 or Peggy Hayes at 617-636-3707.

The Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University is the only independent school of nutrition in the United States. The school's eight centers, which focus on questions relating to famine, hunger, poverty, and communications, are renowned for the application of scientific research to national and international policy. For two decades, the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University has studied the relationship between good nutrition and good health in aging populations. Tufts research scientists work with federal agencies to establish the USDA Dietary Guidelines, the Dietary Reference Intakes, and other significant public policies.


Related medicine news :

1. Quality of life after cancer
2. Steps To Improve Quality Of Plant-Based Drugs
3. Quality of lives of older people
4. Life Quality For Patients With Multiple Sclerosis
5. Relationship Between Genetic Structure And Quality of Life
6. Poorer Quality of Life Observed In Overweight Kids
7. Childhood Obesity May Influence The Their Quality Of Life
8. Indian Hospitals – A Destination For Quality Medical Care
9. The Growing Rise In Clinical Research Could Lead To A Compromise In Quality Of Research And Ethics
10. Quality Awareness In Hospitals Can Reduce Mortality Rate Of Patients
11. Data On Quality Of Health Care Can Be Easily Obtained
Post Your Comments:

(Date:11/27/2015)... ... November 27, 2015 , ... The moment you stop improving ... only fulfilling the needs of advisers and clients but going above and beyond ... top-tier customer service. However, there's always room for improvement, which is why the ...
(Date:11/27/2015)... ... November 27, 2015 , ... Avid collector, Andrew Hawley from Vintage Rock Posters, ... posters. This is one of Joplin's most famous and beautiful concert posters. The concert ... Michigan in Ann Arbor. The According to Hawley, "It is hard to believe that ...
(Date:11/26/2015)... ... 26, 2015 , ... Somu Sivaramakrishnan announced today that he ... now offers travelers, value and care based Travel Services, including exclusive pricing on ... as, cabin upgrades and special amenities such as, shore excursions, discounted fares, travel ...
(Date:11/26/2015)... ... November 26, 2015 , ... Pixel Film Studios brings Final ... ProTrailer: Vintage. This newly styled ProTrailer pack comes with 30 all-new vintage-inspired designs, ... giving users limitless opportunities to stylize and create designs quickly and easily, all ...
(Date:11/25/2015)... ... ... The holiday season is jam-packed with family dinners, parties ... is of the utmost importance. Whether you are cooking at home for the ... try this holiday season. , Turkey Croquettes ,     Ingredients: , ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26 november 2015 AAIPharma Services ... geplande investering aan van ten minste $15,8 ... en het mondiale hoofdkantoor in ... resulteren in extra kantoorruimte en extra capaciteit ... groeiende behoeften van de farmaceutische en biotechnologische ...
(Date:11/26/2015)... 3D bioprinting market is expected to reach ... by Grand View Research Inc. Rising prevalence of chronic diseases ... is expected to boost the market growth, as 3D bioprinting ... --> 3D bioprinting market is expected to reach ... by Grand View Research Inc. Rising prevalence of chronic diseases ...
(Date:11/26/2015)... --> ... att använda SyMRI för att hitta optimal ... med multipel skleros (MS) eller hjärntumörmetastaser och ... för att kunna använda SyMRI Research Edition ... kan man generera flera konstrastbilder från en ...
Breaking Medicine Technology: